| http://purl.uniprot.org/unirules/MF_01667#construct | http://www.w3.org/ns/shacl#construct | "CONSTRUCT {
_:608903 up:source unirule:MF_01667 .
_:608904 up:source unirule:MF_01667 .
_:608905 up:source unirule:MF_01667 .
_:608906 up:source unirule:MF_01667 .
_:608907 up:source unirule:MF_01667 .
_:608908 up:source unirule:MF_01667 .
_:608909 up:source unirule:MF_01667 .
_:608910 up:source unirule:MF_01667 .
_:608911 up:source unirule:MF_01667 .
_:608912 up:source unirule:MF_01667 .
_:608913 up:source unirule:MF_01667 .
_:608914 up:source unirule:MF_01667 .
_:608915 up:source unirule:MF_01667 .
_:608916 up:source unirule:MF_01667 .
_:608917 up:source unirule:MF_01667 .
_:608918 up:source unirule:MF_01667 .
_:608919 up:source unirule:MF_01667 .
_:608920 up:source unirule:MF_01667 .
_:608921 up:source unirule:MF_01667 .
?this up:annotation ?annotation2 ,
?annotation3 ,
?annotation5 ,
?annotation7 ,
?annotation9 ,
?annotation10 ,
?annotation12 ;
up:classifiedWith GO:0005886 ,
GO:0016618 ,
GO:0030267 ,
keyword:520 ,
keyword:521 ,
keyword:560 ,
keyword:963 ;
up:recommendedName ?name0 .
?name0 up:ecName '1.1.1.79' ,
'1.1.1.81' ;
up:fullName 'Glyoxylate/hydroxypyruvate reductase B' ;
rdf:type up:Structured_Name .
?gene1 skos:prefLabel 'ghrB' .
?annotation2 a up:Function_Annotation ;
rdfs:comment 'Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.' .
?annotation3 up:activity ?activity4 ;
rdf:type up:Catalytic_Activity_Annotation .
?activity4 up:catalyticActivity ;
up:enzymeClass .
?annotation5 up:activity ?activity6 ;
rdf:type up:Catalytic_Activity_Annotation .
?activity6 up:catalyticActivity ;
up:enzymeClass .
?annotation7 up:activity ?activity8 ;
rdf:type up:Catalytic_Activity_Annotation .
?activity8 up:catalyticActivity ;
up:enzymeClass .
?annotation9 a up:Subunit_Annotation ;
rdfs:comment 'Homodimer.' .
?annotation10 a up:Subcellular_Location_Annotation .
?annotation10li11 up:cellularComponent .
?annotation12 a up:Similarity_Annotation ;
rdfs:comment 'Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.' .
?pfs13 up:annotation ?annotation14 .
?annotation14 faldo:begin ?pfsb15 ;
faldo:end ?pfse16 ;
rdf:type up:Active_Site_Annotation .
?pfsb15 faldo:position ?thisPositionOn17 ;
rdf:type faldo:ExactPosition .
?pfse16 faldo:position ?thisPositionOn18 ;
rdf:type faldo:ExactPosition .
?pfs19 up:annotation ?annotation20 .
?annotation20 faldo:begin ?pfsb21 ;
faldo:end ?pfse22 ;
rdf:type up:Active_Site_Annotation .
?pfsb21 faldo:position ?thisPositionOn23 ;
rdf:type faldo:ExactPosition .
?pfse22 faldo:position ?thisPositionOn24 ;
rdf:type faldo:ExactPosition .
?pfs25 up:annotation ?annotation26 .
?annotation26 faldo:begin ?pfsb27 ;
faldo:end ?pfse28 ;
rdf:type up:Active_Site_Annotation ;
rdfs:comment 'Proton donor' .
?pfsb27 faldo:position ?thisPositionOn29 ;
rdf:type faldo:ExactPosition .
?pfse28 faldo:position ?thisPositionOn30 ;
rdf:type faldo:ExactPosition .
_:608922 a rdf:Statement ;
up:attribution _:608903 ;
rdf:subject ?this ;
rdf:predicate up:recommendedName ;
rdf:object ?name0 .
_:608923 a rdf:Statement ;
up:attribution _:608904 ;
rdf:subject ?gene1 ;
rdf:predicate up:encodedBy ;
rdf:object ?gene1 .
_:608924 a rdf:Statement ;
up:attribution _:608905 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation2 .
_:608925 a rdf:Statement ;
up:attribution _:608906 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation3 .
_:608926 a rdf:Statement ;
up:attribution _:608907 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation5 .
_:608927 a rdf:Statement ;
up:attribution _:608908 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation7 .
_:608928 a rdf:Statement ;
up:attribution _:608909 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation9 .
_:608929 a rdf:Statement ;
up:attribution _:608910 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation10 .
_:608930 a rdf:Statement ;
up:attribution _:608911 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation12 .
_:608931 a rdf:Statement ;
up:attribution _:608912 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:963 .
_:608932 a rdf:Statement ;
up:attribution _:608913 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:520 .
_:608933 a rdf:Statement ;
up:attribution _:608914 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:521 .
_:608934 a rdf:Statement ;
up:attribution _:608915 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:560 .
_:608935 a rdf:Statement ;
up:attribution _:608916 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0016618 .
_:608936 a rdf:Statement ;
up:attribution _:608917 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0030267 .
_:608937 a rdf:Statement ;
up:attribution _:608918 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0005886 .
_:608938 a rdf:Statement ;
up:source unirule:MF_01667 ;
rdf:subject ?pfs13 ;
rdf:predicate up:annotation ;
rdf:object ?annotation14 .
_:608939 a rdf:Statement ;
up:attribution _:608919 ;
rdf:subject ?pfs13 ;
rdf:predicate up:annotation ;
rdf:object ?annotation14 .
_:608940 a rdf:Statement ;
up:source unirule:MF_01667 ;
rdf:subject ?pfs19 ;
rdf:predicate up:annotation ;
rdf:object ?annotation20 .
_:608941 a rdf:Statement ;
up:attribution _:608920 ;
rdf:subject ?pfs19 ;
rdf:predicate up:annotation ;
rdf:object ?annotation20 .
_:608942 a rdf:Statement ;
up:source unirule:MF_01667 ;
rdf:subject ?pfs25 ;
rdf:predicate up:annotation ;
rdf:object ?annotation26 .
_:608943 a rdf:Statement ;
up:attribution _:608921 ;
rdf:subject ?pfs25 ;
rdf:predicate up:annotation ;
rdf:object ?annotation26 .
}
WHERE {
#baseURI: http://purl.uniprot.org/unirule/MF_01667
#Rule MF_01667 Created by:? on:2008-08-05 Modified by:Edouard de Castro on:2024-09-03
?this up:organism ?thisOrganism ;
rdfs:seeAlso signature:MF_01667 .
?thisOrganism rdfs:subClassOf+ taxon:91347 .
BIND(URI(CONCAT(STR(?this), '#MF_01667a0')) AS ?name0) .
BIND(URI(CONCAT(STR(?this), '#MF_01667a2')) AS ?annotation2) .
BIND(URI(CONCAT(STR(?this), '#MF_01667a3')) AS ?annotation3) .
BIND(URI(CONCAT(STR(?this), '#MF_01667a5')) AS ?annotation5) .
BIND(URI(CONCAT(STR(?this), '#MF_01667a7')) AS ?annotation7) .
BIND(URI(CONCAT(STR(?this), '#MF_01667a9')) AS ?annotation9) .
BIND(URI(CONCAT(STR(?this), '#MF_01667a10')) AS ?annotation10) .
BIND(URI(CONCAT(STR(?this), '#MF_01667a12')) AS ?annotation12) .
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch35 faldo:location ?templateMotifSequenceMatchRegionP3766636 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP3766638 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarP37666MF_0166731 .
?templateMotifSequenceMatchRegionP3766636 faldo:begin ?templateMotifSequenceMatchBeginP3766637 .
?templateMotifSequenceMatchBeginP3766637 faldo:position ?templateMotifSequenceMatchBeginPositionP3766632 ;
faldo:reference isoform:P37666-1 .
?templateMotifSequenceProfileAlignmentOperationP3766638 edam:has_input signature:MF_01667 ;
rdf:type edam:operation_0300 .
?targetMotifMatch39 faldo:location ?targetMotifMatchRegionMatch40 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0166742 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarP37666MF_0166733 .
?targetMotifMatchRegionMatch40 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0166741 .
?targetMotifMatchRegionMatchBeginMF_0166741 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0166734 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0166742 edam:has_input signature:MF_01667 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP37666MF_0166731, 1, (STRLEN(?templateMotifCigarP37666MF_0166731) - STRLEN(REPLACE(?templateMotifCigarP37666MF_0166731, CONCAT('^(?:-*[^-]){', STR(((237 - ?templateMotifSequenceMatchBeginPositionP3766632) + 1)), '}'), '')))), '[a-z]', '')) AS ?step143) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP37666MF_0166733, 1, (STRLEN(?targetMotifMatchCigarP37666MF_0166733) - STRLEN(REPLACE(?targetMotifMatchCigarP37666MF_0166733, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step143), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP37666MF_0166733, 1, (STRLEN(?targetMotifMatchCigarP37666MF_0166733) - STRLEN(REPLACE(?targetMotifMatchCigarP37666MF_0166733, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step143), '}'), '')))), '[^-]', ''))) AS ?step244) .
BIND(((?step244 + ?targetMotifMatchRegionMatchBeginPositionMF_0166734) - 1) AS ?thisPositionOn17) .
BIND(?thisPositionOn17 AS ?thisPositionOn18) .
BIND(?this AS ?pfs1t45) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn17))) AS ?pfsb15) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn18))) AS ?pfse16) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn17, 1) = 'R')) .
BIND(URI(CONCAT(STR(?this), '#MF_01667a14')) AS ?annotation14) .
BIND(?this AS ?pfs13) .
}
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch50 faldo:location ?templateMotifSequenceMatchRegionP3766651 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP3766653 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarP37666MF_0166746 .
?templateMotifSequenceMatchRegionP3766651 faldo:begin ?templateMotifSequenceMatchBeginP3766652 .
?templateMotifSequenceMatchBeginP3766652 faldo:position ?templateMotifSequenceMatchBeginPositionP3766647 ;
faldo:reference isoform:P37666-1 .
?templateMotifSequenceProfileAlignmentOperationP3766653 edam:has_input signature:MF_01667 ;
rdf:type edam:operation_0300 .
?targetMotifMatch54 faldo:location ?targetMotifMatchRegionMatch55 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0166757 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarP37666MF_0166748 .
?targetMotifMatchRegionMatch55 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0166756 .
?targetMotifMatchRegionMatchBeginMF_0166756 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0166749 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0166757 edam:has_input signature:MF_01667 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP37666MF_0166746, 1, (STRLEN(?templateMotifCigarP37666MF_0166746) - STRLEN(REPLACE(?templateMotifCigarP37666MF_0166746, CONCAT('^(?:-*[^-]){', STR(((266 - ?templateMotifSequenceMatchBeginPositionP3766647) + 1)), '}'), '')))), '[a-z]', '')) AS ?step158) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP37666MF_0166748, 1, (STRLEN(?targetMotifMatchCigarP37666MF_0166748) - STRLEN(REPLACE(?targetMotifMatchCigarP37666MF_0166748, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step158), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP37666MF_0166748, 1, (STRLEN(?targetMotifMatchCigarP37666MF_0166748) - STRLEN(REPLACE(?targetMotifMatchCigarP37666MF_0166748, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step158), '}'), '')))), '[^-]', ''))) AS ?step259) .
BIND(((?step259 + ?targetMotifMatchRegionMatchBeginPositionMF_0166749) - 1) AS ?thisPositionOn23) .
BIND(?thisPositionOn23 AS ?thisPositionOn24) .
BIND(?this AS ?pfs1t60) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn23))) AS ?pfsb21) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn24))) AS ?pfse22) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn23, 1) = 'E')) .
BIND(URI(CONCAT(STR(?this), '#MF_01667a20')) AS ?annotation20) .
BIND(?this AS ?pfs19) .
}
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch65 faldo:location ?templateMotifSequenceMatchRegionP3766666 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP3766668 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarP37666MF_0166761 .
?templateMotifSequenceMatchRegionP3766666 faldo:begin ?templateMotifSequenceMatchBeginP3766667 .
?templateMotifSequenceMatchBeginP3766667 faldo:position ?templateMotifSequenceMatchBeginPositionP3766662 ;
faldo:reference isoform:P37666-1 .
?templateMotifSequenceProfileAlignmentOperationP3766668 edam:has_input signature:MF_01667 ;
rdf:type edam:operation_0300 .
?targetMotifMatch69 faldo:location ?targetMotifMatchRegionMatch70 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0166772 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarP37666MF_0166763 .
?targetMotifMatchRegionMatch70 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0166771 .
?targetMotifMatchRegionMatchBeginMF_0166771 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0166764 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0166772 edam:has_input signature:MF_01667 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP37666MF_0166761, 1, (STRLEN(?templateMotifCigarP37666MF_0166761) - STRLEN(REPLACE(?templateMotifCigarP37666MF_0166761, CONCAT('^(?:-*[^-]){', STR(((285 - ?templateMotifSequenceMatchBeginPositionP3766662) + 1)), '}'), '')))), '[a-z]', '')) AS ?step173) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP37666MF_0166763, 1, (STRLEN(?targetMotifMatchCigarP37666MF_0166763) - STRLEN(REPLACE(?targetMotifMatchCigarP37666MF_0166763, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step173), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP37666MF_0166763, 1, (STRLEN(?targetMotifMatchCigarP37666MF_0166763) - STRLEN(REPLACE(?targetMotifMatchCigarP37666MF_0166763, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step173), '}'), '')))), '[^-]', ''))) AS ?step274) .
BIND(((?step274 + ?targetMotifMatchRegionMatchBeginPositionMF_0166764) - 1) AS ?thisPositionOn29) .
BIND(?thisPositionOn29 AS ?thisPositionOn30) .
BIND(?this AS ?pfs1t75) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn29))) AS ?pfsb27) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn30))) AS ?pfse28) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn29, 1) = 'H')) .
BIND(URI(CONCAT(STR(?this), '#MF_01667a26')) AS ?annotation26) .
BIND(?this AS ?pfs25) .
}
}
"xsd:string |