| http://purl.uniprot.org/unirules/MF_01847#construct | http://www.w3.org/ns/shacl#construct | "CONSTRUCT {
_:646598 up:source unirule:MF_01847 .
_:646599 up:source unirule:MF_01847 .
_:646600 up:source unirule:MF_01847 .
_:646601 up:source unirule:MF_01847 .
_:646602 up:source unirule:MF_01847 .
_:646603 up:source unirule:MF_01847 .
_:646604 up:source unirule:MF_01847 .
_:646605 up:source unirule:MF_01847 .
_:646606 up:source unirule:MF_01847 .
_:646607 up:source unirule:MF_01847 .
_:646608 up:source unirule:MF_01847 .
_:646609 up:source unirule:MF_01847 .
_:646610 up:source unirule:MF_01847 .
_:646611 up:source unirule:MF_01847 .
_:646612 up:source unirule:MF_01847 .
?this up:annotation ?annotation2 ,
?annotation3 ,
?annotation5 ,
?annotation6 ;
up:classifiedWith GO:0000287 ,
GO:0016791 ,
keyword:378 ,
keyword:460 ,
keyword:479 ;
up:recommendedName ?name0 .
?name0 up:ecName '3.6.1.-' ;
up:fullName 'HMP-PP phosphatase' ;
rdf:type up:Structured_Name .
?gene1 skos:prefLabel 'cof' .
?annotation2 a up:Function_Annotation ;
rdfs:comment 'Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).' .
?annotation3 up:activity ?activity4 ;
rdf:type up:Catalytic_Activity_Annotation .
?activity4 up:catalyticActivity .
?annotation5 up:cofactor chebi:18420 ;
rdf:type up:Cofactor_Annotation .
?annotation6 a up:Similarity_Annotation ;
rdfs:comment 'Belongs to the HAD-like hydrolase superfamily. Cof family.' .
?pfs7 up:annotation ?annotation8 .
?annotation8 faldo:begin ?pfsb9 ;
faldo:end ?pfse10 ;
rdf:type up:Active_Site_Annotation ;
rdfs:comment 'Nucleophile' .
?pfsb9 faldo:position ?thisPositionOn11 ;
rdf:type faldo:ExactPosition .
?pfse10 faldo:position ?thisPositionOn12 ;
rdf:type faldo:ExactPosition .
?pfs13 up:annotation ?annotation14 .
?annotation14 faldo:begin ?pfsb15 ;
faldo:end ?pfse16 ;
up:ligand ?ligand17 ;
rdf:type up:Binding_Site_Annotation .
?pfsb15 faldo:position ?thisPositionOn18 ;
rdf:type faldo:ExactPosition .
?pfse16 faldo:position ?thisPositionOn19 ;
rdf:type faldo:ExactPosition .
?ligand17 rdfs:subClassOf chebi:18420 .
?pfs20 up:annotation ?annotation21 .
?annotation21 faldo:begin ?pfsb22 ;
faldo:end ?pfse23 ;
up:ligand ?ligand24 ;
rdf:type up:Binding_Site_Annotation .
?pfsb22 faldo:position ?thisPositionOn25 ;
rdf:type faldo:ExactPosition .
?pfse23 faldo:position ?thisPositionOn26 ;
rdf:type faldo:ExactPosition .
?ligand24 rdfs:subClassOf chebi:18420 .
?pfs27 up:annotation ?annotation28 .
?annotation28 faldo:begin ?pfsb29 ;
faldo:end ?pfse30 ;
up:ligand ?ligand31 ;
rdf:type up:Binding_Site_Annotation .
?pfsb29 faldo:position ?thisPositionOn32 ;
rdf:type faldo:ExactPosition .
?pfse30 faldo:position ?thisPositionOn33 ;
rdf:type faldo:ExactPosition .
?ligand31 rdfs:subClassOf chebi:18420 .
_:646613 a rdf:Statement ;
up:attribution _:646598 ;
rdf:subject ?this ;
rdf:predicate up:recommendedName ;
rdf:object ?name0 .
_:646614 a rdf:Statement ;
up:attribution _:646599 ;
rdf:subject ?gene1 ;
rdf:predicate up:encodedBy ;
rdf:object ?gene1 .
_:646615 a rdf:Statement ;
up:attribution _:646600 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation2 .
_:646616 a rdf:Statement ;
up:attribution _:646601 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation3 .
_:646617 a rdf:Statement ;
up:attribution _:646602 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation5 .
_:646618 a rdf:Statement ;
up:attribution _:646603 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation6 .
_:646619 a rdf:Statement ;
up:attribution _:646604 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:378 .
_:646620 a rdf:Statement ;
up:attribution _:646605 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:460 .
_:646621 a rdf:Statement ;
up:attribution _:646606 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:479 .
_:646622 a rdf:Statement ;
up:attribution _:646607 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0000287 .
_:646623 a rdf:Statement ;
up:attribution _:646608 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0016791 .
_:646624 a rdf:Statement ;
up:source unirule:MF_01847 ;
rdf:subject ?pfs7 ;
rdf:predicate up:annotation ;
rdf:object ?annotation8 .
_:646625 a rdf:Statement ;
up:attribution _:646609 ;
rdf:subject ?pfs7 ;
rdf:predicate up:annotation ;
rdf:object ?annotation8 .
_:646626 a rdf:Statement ;
up:source unirule:MF_01847 ;
rdf:subject ?pfs13 ;
rdf:predicate up:annotation ;
rdf:object ?annotation14 .
_:646627 a rdf:Statement ;
up:attribution _:646610 ;
rdf:subject ?pfs13 ;
rdf:predicate up:annotation ;
rdf:object ?annotation14 .
_:646628 a rdf:Statement ;
up:source unirule:MF_01847 ;
rdf:subject ?pfs20 ;
rdf:predicate up:annotation ;
rdf:object ?annotation21 .
_:646629 a rdf:Statement ;
up:attribution _:646611 ;
rdf:subject ?pfs20 ;
rdf:predicate up:annotation ;
rdf:object ?annotation21 .
_:646630 a rdf:Statement ;
up:source unirule:MF_01847 ;
rdf:subject ?pfs27 ;
rdf:predicate up:annotation ;
rdf:object ?annotation28 .
_:646631 a rdf:Statement ;
up:attribution _:646612 ;
rdf:subject ?pfs27 ;
rdf:predicate up:annotation ;
rdf:object ?annotation28 .
}
WHERE {
#baseURI: http://purl.uniprot.org/unirule/MF_01847
#Rule MF_01847 Created by:? on:2008-06-04 Modified by:Edouard de Castro on:2024-09-02
?this up:organism ?thisOrganism ;
rdfs:seeAlso signature:MF_01847 .
?thisOrganism rdfs:subClassOf+ taxon:91347 .
BIND(URI(CONCAT(STR(?this), '#MF_01847a0')) AS ?name0) .
BIND(URI(CONCAT(STR(?this), '#MF_01847a2')) AS ?annotation2) .
BIND(URI(CONCAT(STR(?this), '#MF_01847a3')) AS ?annotation3) .
BIND(URI(CONCAT(STR(?this), '#MF_01847a5')) AS ?annotation5) .
BIND(URI(CONCAT(STR(?this), '#MF_01847a6')) AS ?annotation6) .
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch38 faldo:location ?templateMotifSequenceMatchRegionP4689139 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP4689141 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarP46891MF_0184734 .
?templateMotifSequenceMatchRegionP4689139 faldo:begin ?templateMotifSequenceMatchBeginP4689140 .
?templateMotifSequenceMatchBeginP4689140 faldo:position ?templateMotifSequenceMatchBeginPositionP4689135 ;
faldo:reference isoform:P46891-1 .
?templateMotifSequenceProfileAlignmentOperationP4689141 edam:has_input signature:MF_01847 ;
rdf:type edam:operation_0300 .
?targetMotifMatch42 faldo:location ?targetMotifMatchRegionMatch43 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0184745 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarP46891MF_0184736 .
?targetMotifMatchRegionMatch43 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0184744 .
?targetMotifMatchRegionMatchBeginMF_0184744 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0184737 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0184745 edam:has_input signature:MF_01847 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP46891MF_0184734, 1, (STRLEN(?templateMotifCigarP46891MF_0184734) - STRLEN(REPLACE(?templateMotifCigarP46891MF_0184734, CONCAT('^(?:-*[^-]){', STR(((8 - ?templateMotifSequenceMatchBeginPositionP4689135) + 1)), '}'), '')))), '[a-z]', '')) AS ?step146) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP46891MF_0184736, 1, (STRLEN(?targetMotifMatchCigarP46891MF_0184736) - STRLEN(REPLACE(?targetMotifMatchCigarP46891MF_0184736, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step146), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP46891MF_0184736, 1, (STRLEN(?targetMotifMatchCigarP46891MF_0184736) - STRLEN(REPLACE(?targetMotifMatchCigarP46891MF_0184736, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step146), '}'), '')))), '[^-]', ''))) AS ?step247) .
BIND(((?step247 + ?targetMotifMatchRegionMatchBeginPositionMF_0184737) - 1) AS ?thisPositionOn11) .
BIND(?thisPositionOn11 AS ?thisPositionOn12) .
BIND(?this AS ?pfs1t48) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn11))) AS ?pfsb9) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn12))) AS ?pfse10) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn11, 1) = 'D')) .
BIND(URI(CONCAT(STR(?this), '#MF_01847a8')) AS ?annotation8) .
BIND(?this AS ?pfs7) .
}
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch53 faldo:location ?templateMotifSequenceMatchRegionP4689154 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP4689156 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarP46891MF_0184749 .
?templateMotifSequenceMatchRegionP4689154 faldo:begin ?templateMotifSequenceMatchBeginP4689155 .
?templateMotifSequenceMatchBeginP4689155 faldo:position ?templateMotifSequenceMatchBeginPositionP4689150 ;
faldo:reference isoform:P46891-1 .
?templateMotifSequenceProfileAlignmentOperationP4689156 edam:has_input signature:MF_01847 ;
rdf:type edam:operation_0300 .
?targetMotifMatch57 faldo:location ?targetMotifMatchRegionMatch58 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0184760 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarP46891MF_0184751 .
?targetMotifMatchRegionMatch58 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0184759 .
?targetMotifMatchRegionMatchBeginMF_0184759 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0184752 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0184760 edam:has_input signature:MF_01847 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP46891MF_0184749, 1, (STRLEN(?templateMotifCigarP46891MF_0184749) - STRLEN(REPLACE(?templateMotifCigarP46891MF_0184749, CONCAT('^(?:-*[^-]){', STR(((8 - ?templateMotifSequenceMatchBeginPositionP4689150) + 1)), '}'), '')))), '[a-z]', '')) AS ?step161) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP46891MF_0184751, 1, (STRLEN(?targetMotifMatchCigarP46891MF_0184751) - STRLEN(REPLACE(?targetMotifMatchCigarP46891MF_0184751, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step161), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP46891MF_0184751, 1, (STRLEN(?targetMotifMatchCigarP46891MF_0184751) - STRLEN(REPLACE(?targetMotifMatchCigarP46891MF_0184751, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step161), '}'), '')))), '[^-]', ''))) AS ?step262) .
BIND(((?step262 + ?targetMotifMatchRegionMatchBeginPositionMF_0184752) - 1) AS ?thisPositionOn18) .
BIND(?thisPositionOn18 AS ?thisPositionOn19) .
BIND(?this AS ?pfs1t63) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn18))) AS ?pfsb15) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn19))) AS ?pfse16) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn18, 1) = 'D')) .
BIND(URI(CONCAT(STR(?this), '#MF_01847a14')) AS ?annotation14) .
BIND(?this AS ?pfs13) .
}
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch68 faldo:location ?templateMotifSequenceMatchRegionP4689169 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP4689171 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarP46891MF_0184764 .
?templateMotifSequenceMatchRegionP4689169 faldo:begin ?templateMotifSequenceMatchBeginP4689170 .
?templateMotifSequenceMatchBeginP4689170 faldo:position ?templateMotifSequenceMatchBeginPositionP4689165 ;
faldo:reference isoform:P46891-1 .
?templateMotifSequenceProfileAlignmentOperationP4689171 edam:has_input signature:MF_01847 ;
rdf:type edam:operation_0300 .
?targetMotifMatch72 faldo:location ?targetMotifMatchRegionMatch73 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0184775 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarP46891MF_0184766 .
?targetMotifMatchRegionMatch73 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0184774 .
?targetMotifMatchRegionMatchBeginMF_0184774 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0184767 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0184775 edam:has_input signature:MF_01847 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP46891MF_0184764, 1, (STRLEN(?templateMotifCigarP46891MF_0184764) - STRLEN(REPLACE(?templateMotifCigarP46891MF_0184764, CONCAT('^(?:-*[^-]){', STR(((10 - ?templateMotifSequenceMatchBeginPositionP4689165) + 1)), '}'), '')))), '[a-z]', '')) AS ?step176) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP46891MF_0184766, 1, (STRLEN(?targetMotifMatchCigarP46891MF_0184766) - STRLEN(REPLACE(?targetMotifMatchCigarP46891MF_0184766, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step176), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP46891MF_0184766, 1, (STRLEN(?targetMotifMatchCigarP46891MF_0184766) - STRLEN(REPLACE(?targetMotifMatchCigarP46891MF_0184766, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step176), '}'), '')))), '[^-]', ''))) AS ?step277) .
BIND(((?step277 + ?targetMotifMatchRegionMatchBeginPositionMF_0184767) - 1) AS ?thisPositionOn25) .
BIND(?thisPositionOn25 AS ?thisPositionOn26) .
BIND(?this AS ?pfs1t78) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn25))) AS ?pfsb22) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn26))) AS ?pfse23) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn25, 1) = 'D')) .
BIND(URI(CONCAT(STR(?this), '#MF_01847a21')) AS ?annotation21) .
BIND(?this AS ?pfs20) .
}
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch83 faldo:location ?templateMotifSequenceMatchRegionP4689184 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP4689186 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarP46891MF_0184779 .
?templateMotifSequenceMatchRegionP4689184 faldo:begin ?templateMotifSequenceMatchBeginP4689185 .
?templateMotifSequenceMatchBeginP4689185 faldo:position ?templateMotifSequenceMatchBeginPositionP4689180 ;
faldo:reference isoform:P46891-1 .
?templateMotifSequenceProfileAlignmentOperationP4689186 edam:has_input signature:MF_01847 ;
rdf:type edam:operation_0300 .
?targetMotifMatch87 faldo:location ?targetMotifMatchRegionMatch88 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0184790 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarP46891MF_0184781 .
?targetMotifMatchRegionMatch88 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0184789 .
?targetMotifMatchRegionMatchBeginMF_0184789 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0184782 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0184790 edam:has_input signature:MF_01847 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP46891MF_0184779, 1, (STRLEN(?templateMotifCigarP46891MF_0184779) - STRLEN(REPLACE(?templateMotifCigarP46891MF_0184779, CONCAT('^(?:-*[^-]){', STR(((212 - ?templateMotifSequenceMatchBeginPositionP4689180) + 1)), '}'), '')))), '[a-z]', '')) AS ?step191) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP46891MF_0184781, 1, (STRLEN(?targetMotifMatchCigarP46891MF_0184781) - STRLEN(REPLACE(?targetMotifMatchCigarP46891MF_0184781, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step191), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP46891MF_0184781, 1, (STRLEN(?targetMotifMatchCigarP46891MF_0184781) - STRLEN(REPLACE(?targetMotifMatchCigarP46891MF_0184781, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step191), '}'), '')))), '[^-]', ''))) AS ?step292) .
BIND(((?step292 + ?targetMotifMatchRegionMatchBeginPositionMF_0184782) - 1) AS ?thisPositionOn32) .
BIND(?thisPositionOn32 AS ?thisPositionOn33) .
BIND(?this AS ?pfs1t93) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn32))) AS ?pfsb29) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn33))) AS ?pfse30) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn32, 1) = 'D')) .
BIND(URI(CONCAT(STR(?this), '#MF_01847a28')) AS ?annotation28) .
BIND(?this AS ?pfs27) .
}
}
"xsd:string |