| http://purl.uniprot.org/unirules/MF_02005#construct | http://www.w3.org/ns/shacl#construct | "CONSTRUCT {
_:705491 up:source unirule:MF_02005 .
_:705492 up:source unirule:MF_02005 .
_:705493 up:source unirule:MF_02005 .
_:705494 up:source unirule:MF_02005 .
_:705495 up:source unirule:MF_02005 .
_:705496 up:source unirule:MF_02005 .
_:705497 up:source unirule:MF_02005 .
_:705498 up:source unirule:MF_02005 .
_:705499 up:source unirule:MF_02005 .
_:705500 up:source unirule:MF_02005 .
_:705501 up:source unirule:MF_02005 .
_:705502 up:source unirule:MF_02005 .
_:705503 up:source unirule:MF_02005 .
_:705504 up:source unirule:MF_02005 .
_:705505 up:source unirule:MF_02005 .
_:705506 up:source unirule:MF_02005 .
_:705507 up:source unirule:MF_02005 .
_:705508 up:source unirule:MF_02005 .
_:705509 up:source unirule:MF_02005 .
_:705510 up:source unirule:MF_02005 .
_:705511 up:source unirule:MF_02005 .
?this up:alternativeName ?name1 ;
up:annotation ?annotation3 ,
?annotation4 ,
?annotation6 ,
?annotation8 ,
?annotation9 ;
up:classifiedWith GO:0004832 ,
GO:0005524 ,
GO:0005737 ,
GO:0006438 ,
keyword:30 ,
keyword:436 ,
keyword:547 ,
keyword:648 ,
keyword:67 ,
keyword:963 ;
up:recommendedName ?name0 .
?name0 up:ecName '6.1.1.9' ;
up:fullName 'Valine--tRNA ligase' ;
rdf:type up:Structured_Name .
?name1 up:fullName 'Valyl-tRNA synthetase' ;
up:shortName 'ValRS' ;
rdf:type up:Structured_Name .
?gene2 skos:prefLabel 'valS' .
?annotation3 a up:Function_Annotation ;
rdfs:comment "Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner." .
?annotation4 up:activity ?activity5 ;
rdf:type up:Catalytic_Activity_Annotation .
?activity5 up:catalyticActivity ;
up:enzymeClass .
?annotation6 a up:Subcellular_Location_Annotation .
?annotation6li7 up:cellularComponent .
?annotation8 a up:Domain_Annotation ;
rdfs:comment 'ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.' .
?annotation9 a up:Similarity_Annotation ;
rdfs:comment 'Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.' .
?pfs11 up:annotation ?annotation12 .
?annotation12 faldo:begin ?pfsb13 ;
faldo:end ?pfse14 ;
rdf:type up:Motif_Annotation ;
rdfs:comment "'HIGH' region" .
?pfsb13 faldo:position ?thisPositionOn15 ;
rdf:type faldo:ExactPosition .
?pfse14 faldo:position ?thisPositionOn16 ;
rdf:type faldo:ExactPosition .
?pfs17 up:annotation ?annotation18 .
?annotation18 faldo:begin ?pfsb19 ;
faldo:end ?pfse20 ;
rdf:type up:Motif_Annotation ;
rdfs:comment "'KMSKS' region" .
?pfsb19 faldo:position ?thisPositionOn21 ;
rdf:type faldo:ExactPosition .
?pfse20 faldo:position ?thisPositionOn22 ;
rdf:type faldo:ExactPosition .
?pfs23 up:annotation ?annotation24 .
?annotation24 faldo:begin ?pfsb25 ;
faldo:end ?pfse26 ;
up:ligand ?ligand27 ;
rdf:type up:Binding_Site_Annotation .
?pfsb25 faldo:position ?thisPositionOn28 ;
rdf:type faldo:ExactPosition .
?pfse26 faldo:position ?thisPositionOn29 ;
rdf:type faldo:ExactPosition .
?ligand27 rdfs:subClassOf chebi:30616 .
_:705512 a rdf:Statement ;
up:attribution _:705491 ;
rdf:subject ?this ;
rdf:predicate up:recommendedName ;
rdf:object ?name0 .
_:705513 a rdf:Statement ;
up:attribution _:705492 ;
rdf:subject ?this ;
rdf:predicate up:alternativeName ;
rdf:object ?name1 .
_:705514 a rdf:Statement ;
up:attribution _:705493 ;
rdf:subject ?gene2 ;
rdf:predicate up:encodedBy ;
rdf:object ?gene2 .
_:705515 a rdf:Statement ;
up:attribution _:705494 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation3 .
_:705516 a rdf:Statement ;
up:attribution _:705495 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation4 .
_:705517 a rdf:Statement ;
up:attribution _:705496 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation6 .
_:705518 a rdf:Statement ;
up:attribution _:705497 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation8 .
_:705519 a rdf:Statement ;
up:attribution _:705498 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation9 .
_:705520 a rdf:Statement ;
up:attribution _:705499 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:963 .
_:705521 a rdf:Statement ;
up:attribution _:705500 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:30 .
_:705522 a rdf:Statement ;
up:attribution _:705501 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:67 .
_:705523 a rdf:Statement ;
up:attribution _:705502 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:436 .
_:705524 a rdf:Statement ;
up:attribution _:705503 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:547 .
_:705525 a rdf:Statement ;
up:attribution _:705504 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:648 .
_:705526 a rdf:Statement ;
up:attribution _:705505 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0004832 .
_:705527 a rdf:Statement ;
up:attribution _:705506 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0005524 .
_:705528 a rdf:Statement ;
up:attribution _:705507 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0006438 .
_:705529 a rdf:Statement ;
up:attribution _:705508 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0005737 .
_:705530 a rdf:Statement ;
up:source unirule:MF_02005 ;
rdf:subject ?pfs11 ;
rdf:predicate up:annotation ;
rdf:object ?annotation12 .
_:705531 a rdf:Statement ;
up:attribution _:705509 ;
rdf:subject ?pfs11 ;
rdf:predicate up:annotation ;
rdf:object ?annotation12 .
_:705532 a rdf:Statement ;
up:source unirule:MF_02005 ;
rdf:subject ?pfs17 ;
rdf:predicate up:annotation ;
rdf:object ?annotation18 .
_:705533 a rdf:Statement ;
up:attribution _:705510 ;
rdf:subject ?pfs17 ;
rdf:predicate up:annotation ;
rdf:object ?annotation18 .
_:705534 a rdf:Statement ;
up:source unirule:MF_02005 ;
rdf:subject ?pfs23 ;
rdf:predicate up:annotation ;
rdf:object ?annotation24 .
_:705535 a rdf:Statement ;
up:attribution _:705511 ;
rdf:subject ?pfs23 ;
rdf:predicate up:annotation ;
rdf:object ?annotation24 .
}
WHERE {
#baseURI: http://purl.uniprot.org/unirule/MF_02005
#Rule MF_02005 Created by:? on:2006-02-07 Modified by:Edouard de Castro on:2024-09-03
VALUES ?supertaxon30 {taxon:201174 taxon:766 taxon:2157}
?this up:organism ?thisOrganism ;
rdfs:seeAlso signature:MF_02005 .
?thisOrganism rdfs:subClassOf+ ?supertaxon30 .
BIND(URI(CONCAT(STR(?this), '#MF_02005a0')) AS ?name0) .
BIND(URI(CONCAT(STR(?this), '#MF_02005a1')) AS ?name1) .
BIND(URI(CONCAT(STR(?this), '#MF_02005a3')) AS ?annotation3) .
BIND(URI(CONCAT(STR(?this), '#MF_02005a4')) AS ?annotation4) .
BIND(URI(CONCAT(STR(?this), '#MF_02005a6')) AS ?annotation6) .
BIND(URI(CONCAT(STR(?this), '#MF_02005a8')) AS ?annotation8) .
BIND(URI(CONCAT(STR(?this), '#MF_02005a9')) AS ?annotation9) .
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch35 faldo:location ?templateMotifSequenceMatchRegionQ9ZCN636 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9ZCN638 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarQ9ZCN6MF_0200531 .
?templateMotifSequenceMatchRegionQ9ZCN636 faldo:begin ?templateMotifSequenceMatchBeginQ9ZCN637 .
?templateMotifSequenceMatchBeginQ9ZCN637 faldo:position ?templateMotifSequenceMatchBeginPositionQ9ZCN632 ;
faldo:reference isoform:Q9ZCN6-1 .
?templateMotifSequenceProfileAlignmentOperationQ9ZCN638 edam:has_input signature:MF_02005 ;
rdf:type edam:operation_0300 .
?targetMotifMatch39 faldo:location ?targetMotifMatchRegionMatch40 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0200542 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarQ9ZCN6MF_0200533 .
?targetMotifMatchRegionMatch40 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0200541 .
?targetMotifMatchRegionMatchBeginMF_0200541 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0200534 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0200542 edam:has_input signature:MF_02005 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9ZCN6MF_0200531, 1, (STRLEN(?templateMotifCigarQ9ZCN6MF_0200531) - STRLEN(REPLACE(?templateMotifCigarQ9ZCN6MF_0200531, CONCAT('^(?:-*[^-]){', STR(((46 - ?templateMotifSequenceMatchBeginPositionQ9ZCN632) + 1)), '}'), '')))), '[a-z]', '')) AS ?step143) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200533, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200533) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200533, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step143), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200533, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200533) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200533, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step143), '}'), '')))), '[^-]', ''))) AS ?step244) .
BIND(((?step244 + ?targetMotifMatchRegionMatchBeginPositionMF_0200534) - 1) AS ?thisPositionOn15) .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9ZCN6MF_0200531, 1, (STRLEN(?templateMotifCigarQ9ZCN6MF_0200531) - STRLEN(REPLACE(?templateMotifCigarQ9ZCN6MF_0200531, CONCAT('^(?:-*[^-]){', STR(((56 - ?templateMotifSequenceMatchBeginPositionQ9ZCN632) + 1)), '}'), '')))), '[a-z]', '')) AS ?step145) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200533, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200533) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200533, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step145), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200533, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200533) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200533, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step145), '}'), '')))), '[^-]', ''))) AS ?step246) .
BIND(((?step246 + ?targetMotifMatchRegionMatchBeginPositionMF_0200534) - 1) AS ?thisPositionOn16) .
BIND(?this AS ?pfs1t47) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn15))) AS ?pfsb13) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn16))) AS ?pfse14) .
FILTER (REGEX('P[TYF][ARNDCQEGHILKMFPSTWYVBZJUOX][STA]G[ARNDCQEGHILKMFPSTWYVBZJUOX][ARNDCQEGHILKMFPSTWYVBZJUOX]H[ILMVP]G[HN]', SUBSTR(?thisSequenceValue, ?thisPositionOn15, (?thisPositionOn16 - ?thisPositionOn15)))) .
BIND(URI(CONCAT(STR(?this), '#MF_02005a12')) AS ?annotation12) .
BIND(?this AS ?pfs11) .
}
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch52 faldo:location ?templateMotifSequenceMatchRegionQ9ZCN653 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9ZCN655 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarQ9ZCN6MF_0200548 .
?templateMotifSequenceMatchRegionQ9ZCN653 faldo:begin ?templateMotifSequenceMatchBeginQ9ZCN654 .
?templateMotifSequenceMatchBeginQ9ZCN654 faldo:position ?templateMotifSequenceMatchBeginPositionQ9ZCN649 ;
faldo:reference isoform:Q9ZCN6-1 .
?templateMotifSequenceProfileAlignmentOperationQ9ZCN655 edam:has_input signature:MF_02005 ;
rdf:type edam:operation_0300 .
?targetMotifMatch56 faldo:location ?targetMotifMatchRegionMatch57 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0200559 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarQ9ZCN6MF_0200550 .
?targetMotifMatchRegionMatch57 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0200558 .
?targetMotifMatchRegionMatchBeginMF_0200558 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0200551 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0200559 edam:has_input signature:MF_02005 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9ZCN6MF_0200548, 1, (STRLEN(?templateMotifCigarQ9ZCN6MF_0200548) - STRLEN(REPLACE(?templateMotifCigarQ9ZCN6MF_0200548, CONCAT('^(?:-*[^-]){', STR(((536 - ?templateMotifSequenceMatchBeginPositionQ9ZCN649) + 1)), '}'), '')))), '[a-z]', '')) AS ?step160) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200550, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200550) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200550, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step160), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200550, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200550) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200550, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step160), '}'), '')))), '[^-]', ''))) AS ?step261) .
BIND(((?step261 + ?targetMotifMatchRegionMatchBeginPositionMF_0200551) - 1) AS ?thisPositionOn21) .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9ZCN6MF_0200548, 1, (STRLEN(?templateMotifCigarQ9ZCN6MF_0200548) - STRLEN(REPLACE(?templateMotifCigarQ9ZCN6MF_0200548, CONCAT('^(?:-*[^-]){', STR(((540 - ?templateMotifSequenceMatchBeginPositionQ9ZCN649) + 1)), '}'), '')))), '[a-z]', '')) AS ?step162) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200550, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200550) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200550, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step162), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200550, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200550) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200550, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step162), '}'), '')))), '[^-]', ''))) AS ?step263) .
BIND(((?step263 + ?targetMotifMatchRegionMatchBeginPositionMF_0200551) - 1) AS ?thisPositionOn22) .
BIND(?this AS ?pfs1t64) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn21))) AS ?pfsb19) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn22))) AS ?pfse20) .
FILTER (REGEX('[KRA]MSKS', SUBSTR(?thisSequenceValue, ?thisPositionOn21, (?thisPositionOn22 - ?thisPositionOn21)))) .
BIND(URI(CONCAT(STR(?this), '#MF_02005a18')) AS ?annotation18) .
BIND(?this AS ?pfs17) .
}
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch69 faldo:location ?templateMotifSequenceMatchRegionQ9ZCN670 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ9ZCN672 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarQ9ZCN6MF_0200565 .
?templateMotifSequenceMatchRegionQ9ZCN670 faldo:begin ?templateMotifSequenceMatchBeginQ9ZCN671 .
?templateMotifSequenceMatchBeginQ9ZCN671 faldo:position ?templateMotifSequenceMatchBeginPositionQ9ZCN666 ;
faldo:reference isoform:Q9ZCN6-1 .
?templateMotifSequenceProfileAlignmentOperationQ9ZCN672 edam:has_input signature:MF_02005 ;
rdf:type edam:operation_0300 .
?targetMotifMatch73 faldo:location ?targetMotifMatchRegionMatch74 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0200576 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarQ9ZCN6MF_0200567 .
?targetMotifMatchRegionMatch74 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0200575 .
?targetMotifMatchRegionMatchBeginMF_0200575 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0200568 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0200576 edam:has_input signature:MF_02005 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ9ZCN6MF_0200565, 1, (STRLEN(?templateMotifCigarQ9ZCN6MF_0200565) - STRLEN(REPLACE(?templateMotifCigarQ9ZCN6MF_0200565, CONCAT('^(?:-*[^-]){', STR(((539 - ?templateMotifSequenceMatchBeginPositionQ9ZCN666) + 1)), '}'), '')))), '[a-z]', '')) AS ?step177) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200567, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200567) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200567, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step177), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ9ZCN6MF_0200567, 1, (STRLEN(?targetMotifMatchCigarQ9ZCN6MF_0200567) - STRLEN(REPLACE(?targetMotifMatchCigarQ9ZCN6MF_0200567, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step177), '}'), '')))), '[^-]', ''))) AS ?step278) .
BIND(((?step278 + ?targetMotifMatchRegionMatchBeginPositionMF_0200568) - 1) AS ?thisPositionOn28) .
BIND(?thisPositionOn28 AS ?thisPositionOn29) .
BIND(?this AS ?pfs1t79) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn28))) AS ?pfsb25) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn29))) AS ?pfse26) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn28, 1) = 'K')) .
BIND(URI(CONCAT(STR(?this), '#MF_02005a24')) AS ?annotation24) .
BIND(?this AS ?pfs23) .
}
OPTIONAL {
?this a up:Protein .
?this up:organism ?thisOrganism .
?thisOrganism rdfs:subClassOf+ taxon:2 .
BIND(?this AS ?case10) .
}
}
"xsd:string |
