| http://purl.uniprot.org/unirules/MF_02250#construct | http://www.w3.org/ns/shacl#construct | "CONSTRUCT {
_:778912 up:source unirule:MF_02250 .
_:778913 up:source unirule:MF_02250 .
_:778914 up:source unirule:MF_02250 .
_:778915 up:source unirule:MF_02250 .
_:778916 up:source unirule:MF_02250 .
_:778917 up:source unirule:MF_02250 .
_:778918 up:source unirule:MF_02250 .
_:778919 up:source unirule:MF_02250 .
_:778920 up:source unirule:MF_02250 .
_:778921 up:source unirule:MF_02250 .
_:778922 up:source unirule:MF_02250 .
_:778923 up:source unirule:MF_02250 .
_:778924 up:source unirule:MF_02250 .
_:778925 up:source unirule:MF_02250 .
_:778926 up:source unirule:MF_02250 .
_:778927 up:source unirule:MF_02250 .
?this up:alternativeName ?name1 ;
up:annotation ?annotation3 ,
?annotation4 ,
?annotation6 ,
?annotation7 ,
?annotation8 ;
up:classifiedWith GO:0003920 ,
GO:0032264 ,
keyword:521 ,
keyword:560 ,
keyword:660 ;
up:recommendedName ?name0 .
?name0 up:ecName '1.7.1.7' ;
up:fullName 'GMP reductase' ;
rdf:type up:Structured_Name .
?name1 up:fullName "Guanosine 5'-monophosphate reductase" ;
up:shortName 'GMPR' ;
rdf:type up:Structured_Name .
?gene2 skos:prefLabel 'guaB1' .
?annotation3 a up:Function_Annotation ;
rdfs:comment 'Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP.' .
?annotation4 up:activity ?activity5 ;
rdf:type up:Catalytic_Activity_Annotation .
?activity5 up:catalyticActivity ;
up:enzymeClass .
?annotation6 up:cofactor chebi:60242 ;
rdf:type up:Cofactor_Annotation .
?annotation7 a up:Pathway_Annotation ;
rdfs:comment 'Purine metabolism; IMP biosynthesis via salvage pathway.' .
?annotation8 a up:Similarity_Annotation ;
rdfs:comment 'Belongs to the IMPDH/GMPR family. GuaB1 subfamily.' .
?pfs9 up:annotation ?annotation10 .
?annotation10 faldo:begin ?pfsb11 ;
faldo:end ?pfse12 ;
up:ligand ?ligand13 ;
rdf:type up:Binding_Site_Annotation .
?pfsb11 faldo:position ?thisPositionOn14 ;
rdf:type faldo:ExactPosition .
?pfse12 faldo:position ?thisPositionOn15 ;
rdf:type faldo:ExactPosition .
?ligand13 rdfs:subClassOf chebi:58349 .
?pfs16 up:annotation ?annotation17 .
?annotation17 faldo:begin ?pfsb18 ;
faldo:end ?pfse19 ;
up:ligand ?ligand20 ;
rdf:type up:Binding_Site_Annotation .
?pfsb18 faldo:position ?thisPositionOn21 ;
rdf:type faldo:ExactPosition .
?pfse19 faldo:position ?thisPositionOn22 ;
rdf:type faldo:ExactPosition .
?ligand20 rdfs:subClassOf chebi:58349 .
?pfs23 up:annotation ?annotation24 .
?annotation24 faldo:begin ?pfsb25 ;
faldo:end ?pfse26 ;
rdf:type up:Active_Site_Annotation ;
rdfs:comment 'Thioimidate intermediate' .
?pfsb25 faldo:position ?thisPositionOn27 ;
rdf:type faldo:ExactPosition .
?pfse26 faldo:position ?thisPositionOn28 ;
rdf:type faldo:ExactPosition .
_:778928 a rdf:Statement ;
up:attribution _:778912 ;
rdf:subject ?this ;
rdf:predicate up:recommendedName ;
rdf:object ?name0 .
_:778929 a rdf:Statement ;
up:attribution _:778913 ;
rdf:subject ?this ;
rdf:predicate up:alternativeName ;
rdf:object ?name1 .
_:778930 a rdf:Statement ;
up:attribution _:778914 ;
rdf:subject ?gene2 ;
rdf:predicate up:encodedBy ;
rdf:object ?gene2 .
_:778931 a rdf:Statement ;
up:attribution _:778915 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation3 .
_:778932 a rdf:Statement ;
up:attribution _:778916 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation4 .
_:778933 a rdf:Statement ;
up:attribution _:778917 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation6 .
_:778934 a rdf:Statement ;
up:attribution _:778918 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation7 .
_:778935 a rdf:Statement ;
up:attribution _:778919 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation8 .
_:778936 a rdf:Statement ;
up:attribution _:778920 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:521 .
_:778937 a rdf:Statement ;
up:attribution _:778921 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:560 .
_:778938 a rdf:Statement ;
up:attribution _:778922 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:660 .
_:778939 a rdf:Statement ;
up:attribution _:778923 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0003920 .
_:778940 a rdf:Statement ;
up:attribution _:778924 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0032264 .
_:778941 a rdf:Statement ;
up:source unirule:MF_02250 ;
rdf:subject ?pfs9 ;
rdf:predicate up:annotation ;
rdf:object ?annotation10 .
_:778942 a rdf:Statement ;
up:attribution _:778925 ;
rdf:subject ?pfs9 ;
rdf:predicate up:annotation ;
rdf:object ?annotation10 .
_:778943 a rdf:Statement ;
up:source unirule:MF_02250 ;
rdf:subject ?pfs16 ;
rdf:predicate up:annotation ;
rdf:object ?annotation17 .
_:778944 a rdf:Statement ;
up:attribution _:778926 ;
rdf:subject ?pfs16 ;
rdf:predicate up:annotation ;
rdf:object ?annotation17 .
_:778945 a rdf:Statement ;
up:source unirule:MF_02250 ;
rdf:subject ?pfs23 ;
rdf:predicate up:annotation ;
rdf:object ?annotation24 .
_:778946 a rdf:Statement ;
up:attribution _:778927 ;
rdf:subject ?pfs23 ;
rdf:predicate up:annotation ;
rdf:object ?annotation24 .
}
WHERE {
#baseURI: http://purl.uniprot.org/unirule/MF_02250
#Rule MF_02250 Created by:? on:2022-05-05 Modified by:Edouard de Castro on:2024-09-02
?this up:organism ?thisOrganism ;
rdfs:seeAlso signature:MF_02250 .
?thisOrganism rdfs:subClassOf+ taxon:201174 .
BIND(URI(CONCAT(STR(?this), '#MF_02250a0')) AS ?name0) .
BIND(URI(CONCAT(STR(?this), '#MF_02250a1')) AS ?name1) .
BIND(URI(CONCAT(STR(?this), '#MF_02250a3')) AS ?annotation3) .
BIND(URI(CONCAT(STR(?this), '#MF_02250a4')) AS ?annotation4) .
BIND(URI(CONCAT(STR(?this), '#MF_02250a6')) AS ?annotation6) .
BIND(URI(CONCAT(STR(?this), '#MF_02250a7')) AS ?annotation7) .
BIND(URI(CONCAT(STR(?this), '#MF_02250a8')) AS ?annotation8) .
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch33 faldo:location ?templateMotifSequenceMatchRegionA0QYE834 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationA0QYE836 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarA0QYE8MF_0225029 .
?templateMotifSequenceMatchRegionA0QYE834 faldo:begin ?templateMotifSequenceMatchBeginA0QYE835 .
?templateMotifSequenceMatchBeginA0QYE835 faldo:position ?templateMotifSequenceMatchBeginPositionA0QYE830 ;
faldo:reference isoform:A0QYE8-1 .
?templateMotifSequenceProfileAlignmentOperationA0QYE836 edam:has_input signature:MF_02250 ;
rdf:type edam:operation_0300 .
?targetMotifMatch37 faldo:location ?targetMotifMatchRegionMatch38 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0225040 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarA0QYE8MF_0225031 .
?targetMotifMatchRegionMatch38 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0225039 .
?targetMotifMatchRegionMatchBeginMF_0225039 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0225032 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0225040 edam:has_input signature:MF_02250 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarA0QYE8MF_0225029, 1, (STRLEN(?templateMotifCigarA0QYE8MF_0225029) - STRLEN(REPLACE(?templateMotifCigarA0QYE8MF_0225029, CONCAT('^(?:-*[^-]){', STR(((245 - ?templateMotifSequenceMatchBeginPositionA0QYE830) + 1)), '}'), '')))), '[a-z]', '')) AS ?step141) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarA0QYE8MF_0225031, 1, (STRLEN(?targetMotifMatchCigarA0QYE8MF_0225031) - STRLEN(REPLACE(?targetMotifMatchCigarA0QYE8MF_0225031, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step141), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarA0QYE8MF_0225031, 1, (STRLEN(?targetMotifMatchCigarA0QYE8MF_0225031) - STRLEN(REPLACE(?targetMotifMatchCigarA0QYE8MF_0225031, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step141), '}'), '')))), '[^-]', ''))) AS ?step242) .
BIND(((?step242 + ?targetMotifMatchRegionMatchBeginPositionMF_0225032) - 1) AS ?thisPositionOn14) .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarA0QYE8MF_0225029, 1, (STRLEN(?templateMotifCigarA0QYE8MF_0225029) - STRLEN(REPLACE(?templateMotifCigarA0QYE8MF_0225029, CONCAT('^(?:-*[^-]){', STR(((247 - ?templateMotifSequenceMatchBeginPositionA0QYE830) + 1)), '}'), '')))), '[a-z]', '')) AS ?step143) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarA0QYE8MF_0225031, 1, (STRLEN(?targetMotifMatchCigarA0QYE8MF_0225031) - STRLEN(REPLACE(?targetMotifMatchCigarA0QYE8MF_0225031, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step143), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarA0QYE8MF_0225031, 1, (STRLEN(?targetMotifMatchCigarA0QYE8MF_0225031) - STRLEN(REPLACE(?targetMotifMatchCigarA0QYE8MF_0225031, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step143), '}'), '')))), '[^-]', ''))) AS ?step244) .
BIND(((?step244 + ?targetMotifMatchRegionMatchBeginPositionMF_0225032) - 1) AS ?thisPositionOn15) .
BIND(?this AS ?pfs1t45) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn14))) AS ?pfsb11) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn15))) AS ?pfse12) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn14, (?thisPositionOn15 - ?thisPositionOn14)) = 'DTA')) .
BIND(URI(CONCAT(STR(?this), '#MF_02250a10')) AS ?annotation10) .
BIND(?this AS ?pfs9) .
}
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch50 faldo:location ?templateMotifSequenceMatchRegionA0QYE851 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationA0QYE853 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarA0QYE8MF_0225046 .
?templateMotifSequenceMatchRegionA0QYE851 faldo:begin ?templateMotifSequenceMatchBeginA0QYE852 .
?templateMotifSequenceMatchBeginA0QYE852 faldo:position ?templateMotifSequenceMatchBeginPositionA0QYE847 ;
faldo:reference isoform:A0QYE8-1 .
?templateMotifSequenceProfileAlignmentOperationA0QYE853 edam:has_input signature:MF_02250 ;
rdf:type edam:operation_0300 .
?targetMotifMatch54 faldo:location ?targetMotifMatchRegionMatch55 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0225057 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarA0QYE8MF_0225048 .
?targetMotifMatchRegionMatch55 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0225056 .
?targetMotifMatchRegionMatchBeginMF_0225056 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0225049 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0225057 edam:has_input signature:MF_02250 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarA0QYE8MF_0225046, 1, (STRLEN(?templateMotifCigarA0QYE8MF_0225046) - STRLEN(REPLACE(?templateMotifCigarA0QYE8MF_0225046, CONCAT('^(?:-*[^-]){', STR(((295 - ?templateMotifSequenceMatchBeginPositionA0QYE847) + 1)), '}'), '')))), '[a-z]', '')) AS ?step158) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarA0QYE8MF_0225048, 1, (STRLEN(?targetMotifMatchCigarA0QYE8MF_0225048) - STRLEN(REPLACE(?targetMotifMatchCigarA0QYE8MF_0225048, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step158), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarA0QYE8MF_0225048, 1, (STRLEN(?targetMotifMatchCigarA0QYE8MF_0225048) - STRLEN(REPLACE(?targetMotifMatchCigarA0QYE8MF_0225048, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step158), '}'), '')))), '[^-]', ''))) AS ?step259) .
BIND(((?step259 + ?targetMotifMatchRegionMatchBeginPositionMF_0225049) - 1) AS ?thisPositionOn21) .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarA0QYE8MF_0225046, 1, (STRLEN(?templateMotifCigarA0QYE8MF_0225046) - STRLEN(REPLACE(?templateMotifCigarA0QYE8MF_0225046, CONCAT('^(?:-*[^-]){', STR(((297 - ?templateMotifSequenceMatchBeginPositionA0QYE847) + 1)), '}'), '')))), '[a-z]', '')) AS ?step160) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarA0QYE8MF_0225048, 1, (STRLEN(?targetMotifMatchCigarA0QYE8MF_0225048) - STRLEN(REPLACE(?targetMotifMatchCigarA0QYE8MF_0225048, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step160), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarA0QYE8MF_0225048, 1, (STRLEN(?targetMotifMatchCigarA0QYE8MF_0225048) - STRLEN(REPLACE(?targetMotifMatchCigarA0QYE8MF_0225048, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step160), '}'), '')))), '[^-]', ''))) AS ?step261) .
BIND(((?step261 + ?targetMotifMatchRegionMatchBeginPositionMF_0225049) - 1) AS ?thisPositionOn22) .
BIND(?this AS ?pfs1t62) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn21))) AS ?pfsb18) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn22))) AS ?pfse19) .
FILTER (REGEX('[GN]VG', SUBSTR(?thisSequenceValue, ?thisPositionOn21, (?thisPositionOn22 - ?thisPositionOn21)))) .
BIND(URI(CONCAT(STR(?this), '#MF_02250a17')) AS ?annotation17) .
BIND(?this AS ?pfs16) .
}
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch67 faldo:location ?templateMotifSequenceMatchRegionA0QYE868 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationA0QYE870 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarA0QYE8MF_0225063 .
?templateMotifSequenceMatchRegionA0QYE868 faldo:begin ?templateMotifSequenceMatchBeginA0QYE869 .
?templateMotifSequenceMatchBeginA0QYE869 faldo:position ?templateMotifSequenceMatchBeginPositionA0QYE864 ;
faldo:reference isoform:A0QYE8-1 .
?templateMotifSequenceProfileAlignmentOperationA0QYE870 edam:has_input signature:MF_02250 ;
rdf:type edam:operation_0300 .
?targetMotifMatch71 faldo:location ?targetMotifMatchRegionMatch72 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0225074 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarA0QYE8MF_0225065 .
?targetMotifMatchRegionMatch72 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0225073 .
?targetMotifMatchRegionMatchBeginMF_0225073 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0225066 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0225074 edam:has_input signature:MF_02250 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarA0QYE8MF_0225063, 1, (STRLEN(?templateMotifCigarA0QYE8MF_0225063) - STRLEN(REPLACE(?templateMotifCigarA0QYE8MF_0225063, CONCAT('^(?:-*[^-]){', STR(((302 - ?templateMotifSequenceMatchBeginPositionA0QYE864) + 1)), '}'), '')))), '[a-z]', '')) AS ?step175) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarA0QYE8MF_0225065, 1, (STRLEN(?targetMotifMatchCigarA0QYE8MF_0225065) - STRLEN(REPLACE(?targetMotifMatchCigarA0QYE8MF_0225065, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step175), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarA0QYE8MF_0225065, 1, (STRLEN(?targetMotifMatchCigarA0QYE8MF_0225065) - STRLEN(REPLACE(?targetMotifMatchCigarA0QYE8MF_0225065, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step175), '}'), '')))), '[^-]', ''))) AS ?step276) .
BIND(((?step276 + ?targetMotifMatchRegionMatchBeginPositionMF_0225066) - 1) AS ?thisPositionOn27) .
BIND(?thisPositionOn27 AS ?thisPositionOn28) .
BIND(?this AS ?pfs1t77) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn27))) AS ?pfsb25) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn28))) AS ?pfse26) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn27, 1) = 'C')) .
BIND(URI(CONCAT(STR(?this), '#MF_02250a24')) AS ?annotation24) .
BIND(?this AS ?pfs23) .
}
}
"xsd:string |
