| http://purl.uniprot.org/unirules/MF_03164#construct | http://www.w3.org/ns/shacl#construct | "CONSTRUCT {
_:854028 up:source unirule:MF_03164 .
_:854029 up:source unirule:MF_03164 .
_:854030 up:source unirule:MF_03164 .
_:854031 up:source unirule:MF_03164 .
_:854032 up:source unirule:MF_03164 .
_:854033 up:source unirule:MF_03164 .
_:854034 up:source unirule:MF_03164 .
_:854035 up:source unirule:MF_03164 .
_:854036 up:source unirule:MF_03164 .
_:854037 up:source unirule:MF_03164 .
_:854038 up:source unirule:MF_03164 .
_:854039 up:source unirule:MF_03164 .
_:854040 up:source unirule:MF_03164 .
_:854041 up:source unirule:MF_03164 .
_:854042 up:source unirule:MF_03164 .
_:854043 up:source unirule:MF_03164 .
_:854044 up:source unirule:MF_03164 .
_:854045 up:source unirule:MF_03164 .
_:854046 up:source unirule:MF_03164 .
_:854047 up:source unirule:MF_03164 .
_:854048 up:source unirule:MF_03164 .
_:854049 up:source unirule:MF_03164 .
_:854050 up:source unirule:MF_03164 .
_:854051 up:source unirule:MF_03164 .
?this up:annotation ?annotation2 ,
?annotation3 ,
?annotation5 ,
?annotation6 ,
?annotation7 ,
?annotation9 ;
up:classifiedWith GO:0000287 ,
GO:0003677 ,
GO:0003918 ,
GO:0005634 ,
GO:0006265 ,
GO:0009330 ,
keyword:238 ,
keyword:413 ,
keyword:460 ,
keyword:479 ,
keyword:539 ,
keyword:547 ,
keyword:799 ;
up:recommendedName ?name0 .
?name0 up:ecName '5.6.2.2' ;
up:fullName 'DNA topoisomerase 6 subunit A' ;
rdf:type up:Structured_Name .
?gene1 skos:prefLabel 'TOP6A' .
?annotation2 a up:Function_Annotation ;
rdfs:comment 'Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity.' .
?annotation3 up:activity ?activity4 ;
rdf:type up:Catalytic_Activity_Annotation .
?activity4 up:enzymeClass .
?annotation5 up:cofactor chebi:18420 ;
rdf:type up:Cofactor_Annotation .
?annotation6 a up:Subunit_Annotation ;
rdfs:comment 'Homodimer. Heterotetramer of two TOP6A and two TOP6B subunits.' .
?annotation7 a up:Subcellular_Location_Annotation .
?annotation7li8 up:cellularComponent .
?annotation9 a up:Similarity_Annotation ;
rdfs:comment 'Belongs to the TOP6A family.' .
?pfs10 up:annotation ?annotation11 .
?annotation11 faldo:begin ?pfsb12 ;
faldo:end ?pfse13 ;
rdf:type up:Active_Site_Annotation ;
rdfs:comment 'Nucleophile' .
?pfsb12 faldo:position ?thisPositionOn14 ;
rdf:type faldo:ExactPosition .
?pfse13 faldo:position ?thisPositionOn15 ;
rdf:type faldo:ExactPosition .
?pfs16 up:annotation ?annotation17 .
?annotation17 faldo:begin ?pfsb18 ;
faldo:end ?pfse19 ;
up:ligand ?ligand20 ;
rdf:type up:Binding_Site_Annotation .
?pfsb18 faldo:position ?thisPositionOn21 ;
rdf:type faldo:ExactPosition .
?pfse19 faldo:position ?thisPositionOn22 ;
rdf:type faldo:ExactPosition .
?ligand20 rdfs:subClassOf chebi:18420 .
?pfs23 up:annotation ?annotation24 .
?annotation24 faldo:begin ?pfsb25 ;
faldo:end ?pfse26 ;
up:ligand ?ligand27 ;
rdf:type up:Binding_Site_Annotation .
?pfsb25 faldo:position ?thisPositionOn28 ;
rdf:type faldo:ExactPosition .
?pfse26 faldo:position ?thisPositionOn29 ;
rdf:type faldo:ExactPosition .
?ligand27 rdfs:subClassOf chebi:18420 .
_:854052 a rdf:Statement ;
up:attribution _:854028 ;
rdf:subject ?this ;
rdf:predicate up:recommendedName ;
rdf:object ?name0 .
_:854053 a rdf:Statement ;
up:attribution _:854029 ;
rdf:subject ?gene1 ;
rdf:predicate up:encodedBy ;
rdf:object ?gene1 .
_:854054 a rdf:Statement ;
up:attribution _:854030 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation2 .
_:854055 a rdf:Statement ;
up:attribution _:854031 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation3 .
_:854056 a rdf:Statement ;
up:attribution _:854032 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation5 .
_:854057 a rdf:Statement ;
up:attribution _:854033 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation6 .
_:854058 a rdf:Statement ;
up:attribution _:854034 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation7 .
_:854059 a rdf:Statement ;
up:attribution _:854035 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation9 .
_:854060 a rdf:Statement ;
up:attribution _:854036 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:238 .
_:854061 a rdf:Statement ;
up:attribution _:854037 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:413 .
_:854062 a rdf:Statement ;
up:attribution _:854038 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:460 .
_:854063 a rdf:Statement ;
up:attribution _:854039 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:479 .
_:854064 a rdf:Statement ;
up:attribution _:854040 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:547 .
_:854065 a rdf:Statement ;
up:attribution _:854041 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:539 .
_:854066 a rdf:Statement ;
up:attribution _:854042 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:799 .
_:854067 a rdf:Statement ;
up:attribution _:854043 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0009330 .
_:854068 a rdf:Statement ;
up:attribution _:854044 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0005634 .
_:854069 a rdf:Statement ;
up:attribution _:854045 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0003677 .
_:854070 a rdf:Statement ;
up:attribution _:854046 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0003918 .
_:854071 a rdf:Statement ;
up:attribution _:854047 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0000287 .
_:854072 a rdf:Statement ;
up:attribution _:854048 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0006265 .
_:854073 a rdf:Statement ;
up:source unirule:MF_03164 ;
rdf:subject ?pfs10 ;
rdf:predicate up:annotation ;
rdf:object ?annotation11 .
_:854074 a rdf:Statement ;
up:attribution _:854049 ;
rdf:subject ?pfs10 ;
rdf:predicate up:annotation ;
rdf:object ?annotation11 .
_:854075 a rdf:Statement ;
up:source unirule:MF_03164 ;
rdf:subject ?pfs16 ;
rdf:predicate up:annotation ;
rdf:object ?annotation17 .
_:854076 a rdf:Statement ;
up:attribution _:854050 ;
rdf:subject ?pfs16 ;
rdf:predicate up:annotation ;
rdf:object ?annotation17 .
_:854077 a rdf:Statement ;
up:source unirule:MF_03164 ;
rdf:subject ?pfs23 ;
rdf:predicate up:annotation ;
rdf:object ?annotation24 .
_:854078 a rdf:Statement ;
up:attribution _:854051 ;
rdf:subject ?pfs23 ;
rdf:predicate up:annotation ;
rdf:object ?annotation24 .
}
WHERE {
#baseURI: http://purl.uniprot.org/unirule/MF_03164
#Rule MF_03164 Created by:? on:2013-02-13 Modified by:Edouard de Castro on:2022-11-19
?this up:organism ?thisOrganism ;
rdfs:seeAlso signature:MF_00132 .
?thisOrganism rdfs:subClassOf+ taxon:33090 .
BIND(URI(CONCAT(STR(?this), '#MF_03164a0')) AS ?name0) .
BIND(URI(CONCAT(STR(?this), '#MF_03164a2')) AS ?annotation2) .
BIND(URI(CONCAT(STR(?this), '#MF_03164a3')) AS ?annotation3) .
BIND(URI(CONCAT(STR(?this), '#MF_03164a5')) AS ?annotation5) .
BIND(URI(CONCAT(STR(?this), '#MF_03164a6')) AS ?annotation6) .
BIND(URI(CONCAT(STR(?this), '#MF_03164a7')) AS ?annotation7) .
BIND(URI(CONCAT(STR(?this), '#MF_03164a9')) AS ?annotation9) .
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch34 faldo:location ?templateMotifSequenceMatchRegionQ5781535 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5781537 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarQ57815MF_0013230 .
?templateMotifSequenceMatchRegionQ5781535 faldo:begin ?templateMotifSequenceMatchBeginQ5781536 .
?templateMotifSequenceMatchBeginQ5781536 faldo:position ?templateMotifSequenceMatchBeginPositionQ5781531 ;
faldo:reference isoform:Q57815-1 .
?templateMotifSequenceProfileAlignmentOperationQ5781537 edam:has_input signature:MF_00132 ;
rdf:type edam:operation_0300 .
?targetMotifMatch38 faldo:location ?targetMotifMatchRegionMatch39 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0013241 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarQ57815MF_0013232 .
?targetMotifMatchRegionMatch39 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0013240 .
?targetMotifMatchRegionMatchBeginMF_0013240 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0013233 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0013241 edam:has_input signature:MF_00132 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ57815MF_0013230, 1, (STRLEN(?templateMotifCigarQ57815MF_0013230) - STRLEN(REPLACE(?templateMotifCigarQ57815MF_0013230, CONCAT('^(?:-*[^-]){', STR(((103 - ?templateMotifSequenceMatchBeginPositionQ5781531) + 1)), '}'), '')))), '[a-z]', '')) AS ?step142) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ57815MF_0013232, 1, (STRLEN(?targetMotifMatchCigarQ57815MF_0013232) - STRLEN(REPLACE(?targetMotifMatchCigarQ57815MF_0013232, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step142), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ57815MF_0013232, 1, (STRLEN(?targetMotifMatchCigarQ57815MF_0013232) - STRLEN(REPLACE(?targetMotifMatchCigarQ57815MF_0013232, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step142), '}'), '')))), '[^-]', ''))) AS ?step243) .
BIND(((?step243 + ?targetMotifMatchRegionMatchBeginPositionMF_0013233) - 1) AS ?thisPositionOn14) .
BIND(?thisPositionOn14 AS ?thisPositionOn15) .
BIND(?this AS ?pfs1t44) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn14))) AS ?pfsb12) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn15))) AS ?pfse13) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn14, 1) = 'Y')) .
BIND(URI(CONCAT(STR(?this), '#MF_03164a11')) AS ?annotation11) .
BIND(?this AS ?pfs10) .
}
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch49 faldo:location ?templateMotifSequenceMatchRegionQ5781550 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5781552 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarQ57815MF_0013245 .
?templateMotifSequenceMatchRegionQ5781550 faldo:begin ?templateMotifSequenceMatchBeginQ5781551 .
?templateMotifSequenceMatchBeginQ5781551 faldo:position ?templateMotifSequenceMatchBeginPositionQ5781546 ;
faldo:reference isoform:Q57815-1 .
?templateMotifSequenceProfileAlignmentOperationQ5781552 edam:has_input signature:MF_00132 ;
rdf:type edam:operation_0300 .
?targetMotifMatch53 faldo:location ?targetMotifMatchRegionMatch54 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0013256 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarQ57815MF_0013247 .
?targetMotifMatchRegionMatch54 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0013255 .
?targetMotifMatchRegionMatchBeginMF_0013255 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0013248 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0013256 edam:has_input signature:MF_00132 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ57815MF_0013245, 1, (STRLEN(?templateMotifCigarQ57815MF_0013245) - STRLEN(REPLACE(?templateMotifCigarQ57815MF_0013245, CONCAT('^(?:-*[^-]){', STR(((197 - ?templateMotifSequenceMatchBeginPositionQ5781546) + 1)), '}'), '')))), '[a-z]', '')) AS ?step157) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ57815MF_0013247, 1, (STRLEN(?targetMotifMatchCigarQ57815MF_0013247) - STRLEN(REPLACE(?targetMotifMatchCigarQ57815MF_0013247, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step157), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ57815MF_0013247, 1, (STRLEN(?targetMotifMatchCigarQ57815MF_0013247) - STRLEN(REPLACE(?targetMotifMatchCigarQ57815MF_0013247, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step157), '}'), '')))), '[^-]', ''))) AS ?step258) .
BIND(((?step258 + ?targetMotifMatchRegionMatchBeginPositionMF_0013248) - 1) AS ?thisPositionOn21) .
BIND(?thisPositionOn21 AS ?thisPositionOn22) .
BIND(?this AS ?pfs1t59) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn21))) AS ?pfsb18) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn22))) AS ?pfse19) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn21, 1) = 'E')) .
BIND(URI(CONCAT(STR(?this), '#MF_03164a17')) AS ?annotation17) .
BIND(?this AS ?pfs16) .
}
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch64 faldo:location ?templateMotifSequenceMatchRegionQ5781565 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ5781567 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarQ57815MF_0013260 .
?templateMotifSequenceMatchRegionQ5781565 faldo:begin ?templateMotifSequenceMatchBeginQ5781566 .
?templateMotifSequenceMatchBeginQ5781566 faldo:position ?templateMotifSequenceMatchBeginPositionQ5781561 ;
faldo:reference isoform:Q57815-1 .
?templateMotifSequenceProfileAlignmentOperationQ5781567 edam:has_input signature:MF_00132 ;
rdf:type edam:operation_0300 .
?targetMotifMatch68 faldo:location ?targetMotifMatchRegionMatch69 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0013271 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarQ57815MF_0013262 .
?targetMotifMatchRegionMatch69 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0013270 .
?targetMotifMatchRegionMatchBeginMF_0013270 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0013263 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0013271 edam:has_input signature:MF_00132 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ57815MF_0013260, 1, (STRLEN(?templateMotifCigarQ57815MF_0013260) - STRLEN(REPLACE(?templateMotifCigarQ57815MF_0013260, CONCAT('^(?:-*[^-]){', STR(((249 - ?templateMotifSequenceMatchBeginPositionQ5781561) + 1)), '}'), '')))), '[a-z]', '')) AS ?step172) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ57815MF_0013262, 1, (STRLEN(?targetMotifMatchCigarQ57815MF_0013262) - STRLEN(REPLACE(?targetMotifMatchCigarQ57815MF_0013262, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step172), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ57815MF_0013262, 1, (STRLEN(?targetMotifMatchCigarQ57815MF_0013262) - STRLEN(REPLACE(?targetMotifMatchCigarQ57815MF_0013262, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step172), '}'), '')))), '[^-]', ''))) AS ?step273) .
BIND(((?step273 + ?targetMotifMatchRegionMatchBeginPositionMF_0013263) - 1) AS ?thisPositionOn28) .
BIND(?thisPositionOn28 AS ?thisPositionOn29) .
BIND(?this AS ?pfs1t74) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn28))) AS ?pfsb25) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn29))) AS ?pfse26) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn28, 1) = 'D')) .
BIND(URI(CONCAT(STR(?this), '#MF_03164a24')) AS ?annotation24) .
BIND(?this AS ?pfs23) .
}
}
"xsd:string |
