| http://purl.uniprot.org/unirules/MF_04070#construct | http://www.w3.org/ns/shacl#construct | "CONSTRUCT {
_:925303 up:source unirule:MF_04070 .
_:925304 up:source unirule:MF_04070 .
_:925305 up:source unirule:MF_04070 .
_:925306 up:source unirule:MF_04070 .
_:925307 up:source unirule:MF_04070 .
_:925308 up:source unirule:MF_04070 .
_:925309 up:source unirule:MF_04070 .
_:925310 up:source unirule:MF_04070 .
_:925311 up:source unirule:MF_04070 .
_:925312 up:source unirule:MF_04070 .
_:925313 up:source unirule:MF_04070 .
_:925314 up:source unirule:MF_04070 .
_:925315 up:source unirule:MF_04070 .
_:925316 up:source unirule:MF_04070 .
_:925317 up:source unirule:MF_04070 .
_:925318 up:source unirule:MF_04070 .
_:925319 up:source unirule:MF_04070 .
_:925320 up:source unirule:MF_04070 .
_:925321 up:source unirule:MF_04070 .
_:925322 up:source unirule:MF_04070 .
_:925323 up:source unirule:MF_04070 .
_:925324 up:source unirule:MF_04070 .
_:925325 up:source unirule:MF_04070 .
_:925326 up:source unirule:MF_04070 .
_:925327 up:source unirule:MF_04070 .
_:925328 up:source unirule:MF_04070 .
?this up:alternativeName ?name1 ;
up:annotation ?annotation3 ,
?annotation4 ,
?annotation5 ,
?annotation8 ,
?annotation9 ;
up:classifiedWith GO:0003723 ,
GO:0005198 ,
GO:0019013 ,
GO:0019029 ,
GO:0042025 ,
GO:0075732 ,
keyword:1048 ,
keyword:1139 ,
keyword:1160 ,
keyword:1163 ,
keyword:167 ,
keyword:543 ,
keyword:687 ,
keyword:694 ,
keyword:945 ,
keyword:946 ;
up:recommendedName ?name0 .
?name0 up:fullName 'Nucleoprotein' ;
rdf:type up:Structured_Name .
?name1 up:fullName 'Nucleocapsid protein' ;
up:shortName 'Protein N' ;
rdf:type up:Structured_Name .
?gene2 skos:prefLabel 'NP' .
?annotation3 a up:Function_Annotation ;
rdfs:comment "Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway. Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus." .
?annotation4 a up:Subunit_Annotation ;
rdfs:comment 'Homomultimerizes to form the nucleocapsid. May bind host exportin-1/XPO1. Binds to viral genomic RNA. Protein-RNA contacts are mediated by a combination of electrostatic interactions between positively charged residues and the phosphate backbone and planar interactions between aromatic side chains and bases.' .
?annotation5 a up:Subcellular_Location_Annotation .
?annotation5li6 up:cellularComponent .
?annotation5li7 up:cellularComponent .
?annotation8 a up:PTM_Annotation ;
rdfs:comment 'Late in virus-infected cells, may be cleaved from a 56-kDa protein to a 53-kDa protein by a cellular caspase. This cleavage might be a marker for the onset of apoptosis in infected cells or have a specific function in virus host interaction.' .
?annotation9 a up:Similarity_Annotation ;
rdfs:comment 'Belongs to the influenza viruses nucleoprotein family.' .
?pfs10 up:annotation ?annotation11 .
?annotation11 faldo:begin ?pfsb12 ;
faldo:end ?pfse13 ;
rdf:type up:Motif_Annotation ;
rdfs:comment 'Unconventional nuclear localization signal' .
?pfsb12 faldo:position ?thisPositionOn14 ;
rdf:type faldo:ExactPosition .
?pfse13 faldo:position ?thisPositionOn15 ;
rdf:type faldo:ExactPosition .
?pfs16 up:annotation ?annotation17 .
?annotation17 faldo:begin ?pfsb18 ;
faldo:end ?pfse19 ;
rdf:type up:Motif_Annotation ;
rdfs:comment 'Bipartite nuclear localization signal' .
?pfsb18 faldo:position ?thisPositionOn20 ;
rdf:type faldo:ExactPosition .
?pfse19 faldo:position ?thisPositionOn21 ;
rdf:type faldo:ExactPosition .
_:925329 a rdf:Statement ;
up:attribution _:925303 ;
rdf:subject ?this ;
rdf:predicate up:recommendedName ;
rdf:object ?name0 .
_:925330 a rdf:Statement ;
up:attribution _:925304 ;
rdf:subject ?this ;
rdf:predicate up:alternativeName ;
rdf:object ?name1 .
_:925331 a rdf:Statement ;
up:attribution _:925305 ;
rdf:subject ?gene2 ;
rdf:predicate up:encodedBy ;
rdf:object ?gene2 .
_:925332 a rdf:Statement ;
up:attribution _:925306 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation3 .
_:925333 a rdf:Statement ;
up:attribution _:925307 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation4 .
_:925334 a rdf:Statement ;
up:attribution _:925308 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation5 .
_:925335 a rdf:Statement ;
up:attribution _:925309 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation8 .
_:925336 a rdf:Statement ;
up:attribution _:925310 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation9 .
_:925337 a rdf:Statement ;
up:attribution _:925311 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:167 .
_:925338 a rdf:Statement ;
up:attribution _:925312 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:1139 .
_:925339 a rdf:Statement ;
up:attribution _:925313 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:1048 .
_:925340 a rdf:Statement ;
up:attribution _:925314 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:945 .
_:925341 a rdf:Statement ;
up:attribution _:925315 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:687 .
_:925342 a rdf:Statement ;
up:attribution _:925316 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:694 .
_:925343 a rdf:Statement ;
up:attribution _:925317 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:543 .
_:925344 a rdf:Statement ;
up:attribution _:925318 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:1163 .
_:925345 a rdf:Statement ;
up:attribution _:925319 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:946 .
_:925346 a rdf:Statement ;
up:attribution _:925320 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:1160 .
_:925347 a rdf:Statement ;
up:attribution _:925321 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0019029 .
_:925348 a rdf:Statement ;
up:attribution _:925322 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0042025 .
_:925349 a rdf:Statement ;
up:attribution _:925323 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0019013 .
_:925350 a rdf:Statement ;
up:attribution _:925324 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0003723 .
_:925351 a rdf:Statement ;
up:attribution _:925325 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0005198 .
_:925352 a rdf:Statement ;
up:attribution _:925326 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0075732 .
_:925353 a rdf:Statement ;
up:source unirule:MF_04070 ;
rdf:subject ?pfs10 ;
rdf:predicate up:annotation ;
rdf:object ?annotation11 .
_:925354 a rdf:Statement ;
up:attribution _:925327 ;
rdf:subject ?pfs10 ;
rdf:predicate up:annotation ;
rdf:object ?annotation11 .
_:925355 a rdf:Statement ;
up:source unirule:MF_04070 ;
rdf:subject ?pfs16 ;
rdf:predicate up:annotation ;
rdf:object ?annotation17 .
_:925356 a rdf:Statement ;
up:attribution _:925328 ;
rdf:subject ?pfs16 ;
rdf:predicate up:annotation ;
rdf:object ?annotation17 .
}
WHERE {
#baseURI: http://purl.uniprot.org/unirule/MF_04070
#Rule MF_04070 Created by:? on:2017-04-13 Modified by:Edouard de Castro on:2019-11-20
?this up:organism ?thisOrganism ;
rdfs:seeAlso signature:MF_04070 .
?thisOrganism rdfs:subClassOf+ taxon:11308 .
BIND(URI(CONCAT(STR(?this), '#MF_04070a0')) AS ?name0) .
BIND(URI(CONCAT(STR(?this), '#MF_04070a1')) AS ?name1) .
BIND(URI(CONCAT(STR(?this), '#MF_04070a3')) AS ?annotation3) .
BIND(URI(CONCAT(STR(?this), '#MF_04070a4')) AS ?annotation4) .
BIND(URI(CONCAT(STR(?this), '#MF_04070a5')) AS ?annotation5) .
BIND(URI(CONCAT(STR(?this), '#MF_04070a8')) AS ?annotation8) .
BIND(URI(CONCAT(STR(?this), '#MF_04070a9')) AS ?annotation9) .
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch26 faldo:location ?templateMotifSequenceMatchRegionP0346627 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP0346629 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarP03466MF_0407022 .
?templateMotifSequenceMatchRegionP0346627 faldo:begin ?templateMotifSequenceMatchBeginP0346628 .
?templateMotifSequenceMatchBeginP0346628 faldo:position ?templateMotifSequenceMatchBeginPositionP0346623 ;
faldo:reference isoform:P03466-1 .
?templateMotifSequenceProfileAlignmentOperationP0346629 edam:has_input signature:MF_04070 ;
rdf:type edam:operation_0300 .
?targetMotifMatch30 faldo:location ?targetMotifMatchRegionMatch31 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0407033 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarP03466MF_0407024 .
?targetMotifMatchRegionMatch31 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0407032 .
?targetMotifMatchRegionMatchBeginMF_0407032 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0407025 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0407033 edam:has_input signature:MF_04070 ;
rdf:type edam:operation_0300 .
?this up:organism ?thisOrganism .
?thisOrganism rdfs:subClassOf+ taxon:197911 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP03466MF_0407022, 1, (STRLEN(?templateMotifCigarP03466MF_0407022) - STRLEN(REPLACE(?templateMotifCigarP03466MF_0407022, CONCAT('^(?:-*[^-]){', STR(((1 - ?templateMotifSequenceMatchBeginPositionP0346623) + 1)), '}'), '')))), '[a-z]', '')) AS ?step134) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP03466MF_0407024, 1, (STRLEN(?targetMotifMatchCigarP03466MF_0407024) - STRLEN(REPLACE(?targetMotifMatchCigarP03466MF_0407024, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step134), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP03466MF_0407024, 1, (STRLEN(?targetMotifMatchCigarP03466MF_0407024) - STRLEN(REPLACE(?targetMotifMatchCigarP03466MF_0407024, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step134), '}'), '')))), '[^-]', ''))) AS ?step235) .
BIND(((?step235 + ?targetMotifMatchRegionMatchBeginPositionMF_0407025) - 1) AS ?thisPositionOn14) .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP03466MF_0407022, 1, (STRLEN(?templateMotifCigarP03466MF_0407022) - STRLEN(REPLACE(?templateMotifCigarP03466MF_0407022, CONCAT('^(?:-*[^-]){', STR(((18 - ?templateMotifSequenceMatchBeginPositionP0346623) + 1)), '}'), '')))), '[a-z]', '')) AS ?step136) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP03466MF_0407024, 1, (STRLEN(?targetMotifMatchCigarP03466MF_0407024) - STRLEN(REPLACE(?targetMotifMatchCigarP03466MF_0407024, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step136), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP03466MF_0407024, 1, (STRLEN(?targetMotifMatchCigarP03466MF_0407024) - STRLEN(REPLACE(?targetMotifMatchCigarP03466MF_0407024, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step136), '}'), '')))), '[^-]', ''))) AS ?step237) .
BIND(((?step237 + ?targetMotifMatchRegionMatchBeginPositionMF_0407025) - 1) AS ?thisPositionOn15) .
BIND(?this AS ?pfs1t38) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn14))) AS ?pfsb12) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn15))) AS ?pfse13) .
FILTER ((BOUND(?thisPositionOn14) && BOUND(?thisPositionOn15))) .
BIND(URI(CONCAT(STR(?this), '#MF_04070a11')) AS ?annotation11) .
BIND(?this AS ?pfs10) .
}
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch43 faldo:location ?templateMotifSequenceMatchRegionP0346644 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP0346646 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarP03466MF_0407039 .
?templateMotifSequenceMatchRegionP0346644 faldo:begin ?templateMotifSequenceMatchBeginP0346645 .
?templateMotifSequenceMatchBeginP0346645 faldo:position ?templateMotifSequenceMatchBeginPositionP0346640 ;
faldo:reference isoform:P03466-1 .
?templateMotifSequenceProfileAlignmentOperationP0346646 edam:has_input signature:MF_04070 ;
rdf:type edam:operation_0300 .
?targetMotifMatch47 faldo:location ?targetMotifMatchRegionMatch48 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0407050 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarP03466MF_0407041 .
?targetMotifMatchRegionMatch48 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0407049 .
?targetMotifMatchRegionMatchBeginMF_0407049 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0407042 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0407050 edam:has_input signature:MF_04070 ;
rdf:type edam:operation_0300 .
?this up:organism ?thisOrganism .
?thisOrganism rdfs:subClassOf+ taxon:197911 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP03466MF_0407039, 1, (STRLEN(?templateMotifCigarP03466MF_0407039) - STRLEN(REPLACE(?templateMotifCigarP03466MF_0407039, CONCAT('^(?:-*[^-]){', STR(((198 - ?templateMotifSequenceMatchBeginPositionP0346640) + 1)), '}'), '')))), '[a-z]', '')) AS ?step151) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP03466MF_0407041, 1, (STRLEN(?targetMotifMatchCigarP03466MF_0407041) - STRLEN(REPLACE(?targetMotifMatchCigarP03466MF_0407041, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step151), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP03466MF_0407041, 1, (STRLEN(?targetMotifMatchCigarP03466MF_0407041) - STRLEN(REPLACE(?targetMotifMatchCigarP03466MF_0407041, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step151), '}'), '')))), '[^-]', ''))) AS ?step252) .
BIND(((?step252 + ?targetMotifMatchRegionMatchBeginPositionMF_0407042) - 1) AS ?thisPositionOn20) .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP03466MF_0407039, 1, (STRLEN(?templateMotifCigarP03466MF_0407039) - STRLEN(REPLACE(?templateMotifCigarP03466MF_0407039, CONCAT('^(?:-*[^-]){', STR(((216 - ?templateMotifSequenceMatchBeginPositionP0346640) + 1)), '}'), '')))), '[a-z]', '')) AS ?step153) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP03466MF_0407041, 1, (STRLEN(?targetMotifMatchCigarP03466MF_0407041) - STRLEN(REPLACE(?targetMotifMatchCigarP03466MF_0407041, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step153), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP03466MF_0407041, 1, (STRLEN(?targetMotifMatchCigarP03466MF_0407041) - STRLEN(REPLACE(?targetMotifMatchCigarP03466MF_0407041, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step153), '}'), '')))), '[^-]', ''))) AS ?step254) .
BIND(((?step254 + ?targetMotifMatchRegionMatchBeginPositionMF_0407042) - 1) AS ?thisPositionOn21) .
BIND(?this AS ?pfs1t55) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn20))) AS ?pfsb18) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn21))) AS ?pfse19) .
FILTER ((BOUND(?thisPositionOn20) && BOUND(?thisPositionOn21))) .
BIND(URI(CONCAT(STR(?this), '#MF_04070a17')) AS ?annotation17) .
BIND(?this AS ?pfs16) .
}
}
"xsd:string |
