| http://purl.uniprot.org/unirules/MF_00782#construct | http://www.w3.org/ns/shacl#construct | "CONSTRUCT {
_:282350 up:source unirule:MF_00782 .
_:282351 up:source unirule:MF_00782 .
_:282352 up:ecName '6.3.2.2' ;
up:fullName 'Glutamate--cysteine ligase' ;
rdf:type up:Structured_Name .
_:282353 up:fullName 'Gamma-ECS' ;
up:shortName 'GCS' ;
rdf:type up:Structured_Name .
_:282354 up:fullName 'Gamma-glutamylcysteine synthetase' ;
rdf:type up:Structured_Name .
_:282355 up:source unirule:MF_00782 .
_:282356 up:ecName '6.3.2.3' ;
up:fullName 'Glutathione synthetase' ;
rdf:type up:Structured_Name .
_:282357 up:fullName 'GSH synthetase' ;
up:shortName 'GS' ,
'GSH-S' ,
'GSHase' ;
rdf:type up:Structured_Name .
_:282358 up:fullName 'Glutathione synthase' ;
rdf:type up:Structured_Name .
_:282359 up:source unirule:MF_00782 .
_:282360 up:source unirule:MF_00782 .
_:282361 up:source unirule:MF_00782 .
_:282362 up:source unirule:MF_00782 .
_:282363 up:source unirule:MF_00782 .
_:282364 up:source unirule:MF_00782 .
_:282365 up:source unirule:MF_00782 .
_:282366 up:source unirule:MF_00782 .
_:282367 up:source unirule:MF_00782 .
_:282368 up:source unirule:MF_00782 .
_:282369 up:source unirule:MF_00782 .
_:282370 up:source unirule:MF_00782 .
_:282371 up:source unirule:MF_00782 .
_:282372 up:source unirule:MF_00782 .
_:282373 up:source unirule:MF_00782 .
_:282374 up:source unirule:MF_00782 .
_:282375 up:source unirule:MF_00782 .
_:282376 up:source unirule:MF_00782 .
_:282377 up:source unirule:MF_00782 .
?this up:alternativeName ?name1 ;
up:annotation ?annotation5 ,
?annotation6 ,
?annotation8 ,
?annotation10 ,
?annotation11 ,
?annotation12 ,
?annotation13 ;
up:classifiedWith GO:0004357 ,
GO:0004363 ,
GO:0005524 ,
GO:0006750 ,
keyword:317 ,
keyword:436 ,
keyword:511 ,
keyword:547 ,
keyword:67 ;
up:domain ?namedpart2 ,
?namedpart3 ;
up:recommendedName ?name0 .
?name0 up:fullName 'Glutathione biosynthesis bifunctional protein GshAB' ;
rdf:type up:Structured_Name .
?name1 up:fullName 'Gamma-GCS-GS' ;
up:shortName 'GCS-GS' ;
rdf:type up:Structured_Name .
?namedpart2 up:alternativeName _:282353 ,
_:282354 ;
up:recommendedName _:282352 .
?namedpart3 up:alternativeName _:282357 ,
_:282358 ;
up:recommendedName _:282356 .
?gene4 skos:altLabel 'gshF' ;
skos:prefLabel 'gshAB' .
?annotation5 a up:Function_Annotation ;
rdfs:comment 'Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.' .
?annotation6 up:activity ?activity7 ;
rdf:type up:Catalytic_Activity_Annotation .
?activity7 up:catalyticActivity ;
up:enzymeClass .
?annotation8 up:activity ?activity9 ;
rdf:type up:Catalytic_Activity_Annotation .
?activity9 up:catalyticActivity ;
up:enzymeClass .
?annotation10 a up:Pathway_Annotation ;
rdfs:comment 'Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.' .
?annotation11 a up:Pathway_Annotation ;
rdfs:comment 'Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.' .
?annotation12 a up:Subunit_Annotation ;
rdfs:comment 'Monomer.' .
?annotation13 a up:Similarity_Annotation ;
rdfs:comment 'In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.' .
?pfs14 up:annotation ?annotation15 .
?annotation15 faldo:begin ?pfsb16 ;
faldo:end ?pfse17 ;
rdf:type up:Region_Annotation ;
rdfs:comment 'Glutamate--cysteine ligase' .
?pfsb16 faldo:position ?thisPositionOn18 ;
rdf:type faldo:ExactPosition .
?pfse17 faldo:position ?thisPositionOn19 ;
rdf:type faldo:ExactPosition .
_:282378 a rdf:Statement ;
up:attribution _:282350 ;
rdf:subject ?this ;
rdf:predicate up:recommendedName ;
rdf:object ?name0 .
_:282379 a rdf:Statement ;
up:attribution _:282351 ;
rdf:subject ?this ;
rdf:predicate up:alternativeName ;
rdf:object ?name1 .
_:282380 a rdf:Statement ;
up:attribution _:282355 ;
rdf:subject ?this ;
rdf:predicate up:domain ;
rdf:object ?namedpart2 .
_:282381 a rdf:Statement ;
up:attribution _:282359 ;
rdf:subject ?this ;
rdf:predicate up:domain ;
rdf:object ?namedpart3 .
_:282382 a rdf:Statement ;
up:attribution _:282360 ;
rdf:subject ?gene4 ;
rdf:predicate up:encodedBy ;
rdf:object ?gene4 .
_:282383 a rdf:Statement ;
up:attribution _:282361 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation5 .
_:282384 a rdf:Statement ;
up:attribution _:282362 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation6 .
_:282385 a rdf:Statement ;
up:attribution _:282363 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation8 .
_:282386 a rdf:Statement ;
up:attribution _:282364 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation10 .
_:282387 a rdf:Statement ;
up:attribution _:282365 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation11 .
_:282388 a rdf:Statement ;
up:attribution _:282366 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation12 .
_:282389 a rdf:Statement ;
up:attribution _:282367 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation13 .
_:282390 a rdf:Statement ;
up:attribution _:282368 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:67 .
_:282391 a rdf:Statement ;
up:attribution _:282369 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:317 .
_:282392 a rdf:Statement ;
up:attribution _:282370 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:436 .
_:282393 a rdf:Statement ;
up:attribution _:282371 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:511 .
_:282394 a rdf:Statement ;
up:attribution _:282372 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:547 .
_:282395 a rdf:Statement ;
up:attribution _:282373 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0005524 .
_:282396 a rdf:Statement ;
up:attribution _:282374 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0004363 .
_:282397 a rdf:Statement ;
up:attribution _:282375 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0004357 .
_:282398 a rdf:Statement ;
up:attribution _:282376 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0006750 .
_:282399 a rdf:Statement ;
up:source unirule:MF_00782 ;
rdf:subject ?pfs14 ;
rdf:predicate up:annotation ;
rdf:object ?annotation15 .
_:282400 a rdf:Statement ;
up:attribution _:282377 ;
rdf:subject ?pfs14 ;
rdf:predicate up:annotation ;
rdf:object ?annotation15 .
}
WHERE {
#baseURI: http://purl.uniprot.org/unirule/MF_00782
#Rule MF_00782 Created by:? on:2005-02-28 Modified by:Edouard de Castro on:2024-09-02
VALUES ?supertaxon20 {taxon:1239 taxon:1224}
?this up:organism ?thisOrganism ;
rdfs:seeAlso signature:MF_00782 .
?thisOrganism rdfs:subClassOf+ ?supertaxon20 .
BIND(URI(CONCAT(STR(?this), '#MF_00782a0')) AS ?name0) .
BIND(URI(CONCAT(STR(?this), '#MF_00782a1')) AS ?name1) .
BIND(URI(CONCAT(STR(?this), '#MF_00782a2')) AS ?namedpart2) .
BIND(URI(CONCAT(STR(?this), '#MF_00782a3')) AS ?namedpart3) .
BIND(URI(CONCAT(STR(?this), '#MF_00782a5')) AS ?annotation5) .
BIND(URI(CONCAT(STR(?this), '#MF_00782a6')) AS ?annotation6) .
BIND(URI(CONCAT(STR(?this), '#MF_00782a8')) AS ?annotation8) .
BIND(URI(CONCAT(STR(?this), '#MF_00782a10')) AS ?annotation10) .
BIND(URI(CONCAT(STR(?this), '#MF_00782a11')) AS ?annotation11) .
BIND(URI(CONCAT(STR(?this), '#MF_00782a12')) AS ?annotation12) .
BIND(URI(CONCAT(STR(?this), '#MF_00782a13')) AS ?annotation13) .
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch25 faldo:location ?templateMotifSequenceMatchRegionQ8DXM926 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationQ8DXM928 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarQ8DXM9MF_0078221 .
?templateMotifSequenceMatchRegionQ8DXM926 faldo:begin ?templateMotifSequenceMatchBeginQ8DXM927 .
?templateMotifSequenceMatchBeginQ8DXM927 faldo:position ?templateMotifSequenceMatchBeginPositionQ8DXM922 ;
faldo:reference isoform:Q8DXM9-1 .
?templateMotifSequenceProfileAlignmentOperationQ8DXM928 edam:has_input signature:MF_00782 ;
rdf:type edam:operation_0300 .
?targetMotifMatch29 faldo:location ?targetMotifMatchRegionMatch30 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0078232 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarQ8DXM9MF_0078223 .
?targetMotifMatchRegionMatch30 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0078231 .
?targetMotifMatchRegionMatchBeginMF_0078231 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0078224 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0078232 edam:has_input signature:MF_00782 ;
rdf:type edam:operation_0300 .
BIND(1 AS ?thisPositionOn18) .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarQ8DXM9MF_0078221, 1, (STRLEN(?templateMotifCigarQ8DXM9MF_0078221) - STRLEN(REPLACE(?templateMotifCigarQ8DXM9MF_0078221, CONCAT('^(?:-*[^-]){', STR(((333 - ?templateMotifSequenceMatchBeginPositionQ8DXM922) + 1)), '}'), '')))), '[a-z]', '')) AS ?step133) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarQ8DXM9MF_0078223, 1, (STRLEN(?targetMotifMatchCigarQ8DXM9MF_0078223) - STRLEN(REPLACE(?targetMotifMatchCigarQ8DXM9MF_0078223, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step133), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarQ8DXM9MF_0078223, 1, (STRLEN(?targetMotifMatchCigarQ8DXM9MF_0078223) - STRLEN(REPLACE(?targetMotifMatchCigarQ8DXM9MF_0078223, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step133), '}'), '')))), '[^-]', ''))) AS ?step234) .
BIND(((?step234 + ?targetMotifMatchRegionMatchBeginPositionMF_0078224) - 1) AS ?thisPositionOn19) .
BIND(?this AS ?pfs1t35) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn18))) AS ?pfsb16) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn19))) AS ?pfse17) .
FILTER ((BOUND(?thisPositionOn18) && BOUND(?thisPositionOn19))) .
BIND(URI(CONCAT(STR(?this), '#MF_00782a15')) AS ?annotation15) .
BIND(?this AS ?pfs14) .
}
}
"xsd:string |
