| http://purl.uniprot.org/unirules/MF_00384#construct | http://www.w3.org/ns/shacl#construct | "CONSTRUCT {
_:152159 up:source unirule:MF_00384 .
_:152160 up:source unirule:MF_00384 .
_:152161 up:source unirule:MF_00384 .
_:152162 up:source unirule:MF_00384 .
_:152163 up:source unirule:MF_00384 .
_:152164 up:source unirule:MF_00384 .
_:152165 up:source unirule:MF_00384 .
_:152166 up:source unirule:MF_00384 .
_:152167 up:source unirule:MF_00384 .
_:152168 up:source unirule:MF_00384 .
_:152169 up:source unirule:MF_00384 .
_:152170 up:source unirule:MF_00384 .
_:152171 up:source unirule:MF_00384 .
_:152172 up:source unirule:MF_00384 .
_:152173 up:source unirule:MF_00384 .
_:152174 up:source unirule:MF_00384 .
_:152175 up:source unirule:MF_00384 .
_:152176 up:source unirule:MF_00384 .
_:152177 up:source unirule:MF_00384 .
?this up:annotation ?annotation2 ,
?annotation3 ,
?annotation5 ,
?annotation6 ,
?annotation8 ;
up:classifiedWith GO:0004413 ,
GO:0005524 ,
GO:0005737 ,
GO:0009088 ,
keyword:28 ,
keyword:418 ,
keyword:547 ,
keyword:67 ,
keyword:791 ,
keyword:808 ,
keyword:963 ;
up:recommendedName ?name0 .
?name0 up:ecName '2.7.1.39' ;
up:fullName 'Homoserine kinase' ;
up:shortName 'HK' ,
'HSK' ;
rdf:type up:Structured_Name .
?gene1 skos:prefLabel 'thrB' .
?annotation2 a up:Function_Annotation ;
rdfs:comment 'Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.' .
?annotation3 up:activity ?activity4 ;
rdf:type up:Catalytic_Activity_Annotation .
?activity4 up:catalyticActivity ;
up:enzymeClass .
?annotation5 a up:Pathway_Annotation ;
rdfs:comment 'Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.' .
?annotation6 a up:Subcellular_Location_Annotation .
?annotation6li7 up:cellularComponent .
?annotation8 a up:Similarity_Annotation ;
rdfs:comment 'Belongs to the GHMP kinase family. Homoserine kinase subfamily.' .
?pfs9 up:annotation ?annotation10 .
?annotation10 faldo:begin ?pfsb11 ;
faldo:end ?pfse12 ;
up:ligand ?ligand13 ;
rdf:type up:Binding_Site_Annotation .
?pfsb11 faldo:position ?thisPositionOn14 ;
rdf:type faldo:ExactPosition .
?pfse12 faldo:position ?thisPositionOn15 ;
rdf:type faldo:ExactPosition .
?ligand13 rdfs:subClassOf chebi:30616 .
_:152178 a rdf:Statement ;
up:attribution _:152159 ;
rdf:subject ?this ;
rdf:predicate up:recommendedName ;
rdf:object ?name0 .
_:152179 a rdf:Statement ;
up:attribution _:152160 ;
rdf:subject ?gene1 ;
rdf:predicate up:encodedBy ;
rdf:object ?gene1 .
_:152180 a rdf:Statement ;
up:attribution _:152161 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation2 .
_:152181 a rdf:Statement ;
up:attribution _:152162 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation3 .
_:152182 a rdf:Statement ;
up:attribution _:152163 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation5 .
_:152183 a rdf:Statement ;
up:attribution _:152164 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation6 .
_:152184 a rdf:Statement ;
up:attribution _:152165 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation8 .
_:152185 a rdf:Statement ;
up:attribution _:152166 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:963 .
_:152186 a rdf:Statement ;
up:attribution _:152167 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:28 .
_:152187 a rdf:Statement ;
up:attribution _:152168 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:791 .
_:152188 a rdf:Statement ;
up:attribution _:152169 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:808 .
_:152189 a rdf:Statement ;
up:attribution _:152170 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:418 .
_:152190 a rdf:Statement ;
up:attribution _:152171 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:67 .
_:152191 a rdf:Statement ;
up:attribution _:152172 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:547 .
_:152192 a rdf:Statement ;
up:attribution _:152173 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0005524 .
_:152193 a rdf:Statement ;
up:attribution _:152174 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0004413 .
_:152194 a rdf:Statement ;
up:attribution _:152175 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0009088 .
_:152195 a rdf:Statement ;
up:attribution _:152176 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0005737 .
_:152196 a rdf:Statement ;
up:source unirule:MF_00384 ;
rdf:subject ?pfs9 ;
rdf:predicate up:annotation ;
rdf:object ?annotation10 .
_:152197 a rdf:Statement ;
up:attribution _:152177 ;
rdf:subject ?pfs9 ;
rdf:predicate up:annotation ;
rdf:object ?annotation10 .
}
WHERE {
#baseURI: http://purl.uniprot.org/unirule/MF_00384
#Rule MF_00384 Created by:? on:2005-02-28 Modified by:Edouard de Castro on:2024-09-02
VALUES ?supertaxon16 {taxon:2 taxon:2157}
?this up:organism ?thisOrganism ;
rdfs:seeAlso signature:MF_00384 .
?thisOrganism rdfs:subClassOf+ ?supertaxon16 .
BIND(URI(CONCAT(STR(?this), '#MF_00384a0')) AS ?name0) .
BIND(URI(CONCAT(STR(?this), '#MF_00384a2')) AS ?annotation2) .
BIND(URI(CONCAT(STR(?this), '#MF_00384a3')) AS ?annotation3) .
BIND(URI(CONCAT(STR(?this), '#MF_00384a5')) AS ?annotation5) .
BIND(URI(CONCAT(STR(?this), '#MF_00384a6')) AS ?annotation6) .
BIND(URI(CONCAT(STR(?this), '#MF_00384a8')) AS ?annotation8) .
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch21 faldo:location ?templateMotifSequenceMatchRegionP0054722 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP0054724 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarP00547MF_0038417 .
?templateMotifSequenceMatchRegionP0054722 faldo:begin ?templateMotifSequenceMatchBeginP0054723 .
?templateMotifSequenceMatchBeginP0054723 faldo:position ?templateMotifSequenceMatchBeginPositionP0054718 ;
faldo:reference isoform:P00547-1 .
?templateMotifSequenceProfileAlignmentOperationP0054724 edam:has_input signature:MF_00384 ;
rdf:type edam:operation_0300 .
?targetMotifMatch25 faldo:location ?targetMotifMatchRegionMatch26 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0038428 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarP00547MF_0038419 .
?targetMotifMatchRegionMatch26 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0038427 .
?targetMotifMatchRegionMatchBeginMF_0038427 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0038420 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0038428 edam:has_input signature:MF_00384 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP00547MF_0038417, 1, (STRLEN(?templateMotifCigarP00547MF_0038417) - STRLEN(REPLACE(?templateMotifCigarP00547MF_0038417, CONCAT('^(?:-*[^-]){', STR(((91 - ?templateMotifSequenceMatchBeginPositionP0054718) + 1)), '}'), '')))), '[a-z]', '')) AS ?step129) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP00547MF_0038419, 1, (STRLEN(?targetMotifMatchCigarP00547MF_0038419) - STRLEN(REPLACE(?targetMotifMatchCigarP00547MF_0038419, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step129), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP00547MF_0038419, 1, (STRLEN(?targetMotifMatchCigarP00547MF_0038419) - STRLEN(REPLACE(?targetMotifMatchCigarP00547MF_0038419, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step129), '}'), '')))), '[^-]', ''))) AS ?step230) .
BIND(((?step230 + ?targetMotifMatchRegionMatchBeginPositionMF_0038420) - 1) AS ?thisPositionOn14) .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP00547MF_0038417, 1, (STRLEN(?templateMotifCigarP00547MF_0038417) - STRLEN(REPLACE(?templateMotifCigarP00547MF_0038417, CONCAT('^(?:-*[^-]){', STR(((101 - ?templateMotifSequenceMatchBeginPositionP0054718) + 1)), '}'), '')))), '[a-z]', '')) AS ?step131) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP00547MF_0038419, 1, (STRLEN(?targetMotifMatchCigarP00547MF_0038419) - STRLEN(REPLACE(?targetMotifMatchCigarP00547MF_0038419, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step131), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP00547MF_0038419, 1, (STRLEN(?targetMotifMatchCigarP00547MF_0038419) - STRLEN(REPLACE(?targetMotifMatchCigarP00547MF_0038419, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step131), '}'), '')))), '[^-]', ''))) AS ?step232) .
BIND(((?step232 + ?targetMotifMatchRegionMatchBeginPositionMF_0038420) - 1) AS ?thisPositionOn15) .
BIND(?this AS ?pfs1t33) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn14))) AS ?pfsb11) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn15))) AS ?pfse12) .
FILTER (REGEX('[APKR][ARNDCQEGHILKMFPSTWYVBZJUOX]{3)G[LFM]G[GS]S[GSA][STAC]', SUBSTR(?thisSequenceValue, ?thisPositionOn14, (?thisPositionOn15 - ?thisPositionOn14)))) .
BIND(URI(CONCAT(STR(?this), '#MF_00384a10')) AS ?annotation10) .
BIND(?this AS ?pfs9) .
}
}
"xsd:string |