| http://purl.uniprot.org/unirules/MF_04031#construct | http://www.w3.org/ns/shacl#construct | "CONSTRUCT {
_:904843 up:source unirule:MF_04031 .
_:904844 up:source unirule:MF_04031 .
_:904845 up:source unirule:MF_04031 .
_:904846 up:source unirule:MF_04031 .
_:904847 up:source unirule:MF_04031 .
_:904848 up:source unirule:MF_04031 .
_:904849 up:source unirule:MF_04031 .
_:904850 up:source unirule:MF_04031 .
_:904851 up:source unirule:MF_04031 .
_:904852 up:source unirule:MF_04031 .
_:904853 up:source unirule:MF_04031 .
_:904854 up:source unirule:MF_04031 .
_:904855 up:source unirule:MF_04031 .
_:904856 up:source unirule:MF_04031 .
_:904857 up:source unirule:MF_04031 .
_:904858 up:source unirule:MF_04031 .
?this up:alternativeName ?name1 ;
up:annotation ?annotation3 ,
?annotation4 ,
?annotation6 ,
?annotation7 ;
up:classifiedWith GO:0004170 ,
GO:0046080 ,
GO:0046872 ,
keyword:378 ,
keyword:460 ,
keyword:479 ,
keyword:546 ;
up:recommendedName ?name0 .
?name0 up:ecName '3.6.1.23' ;
up:fullName "Deoxyuridine 5'-triphosphate nucleotidohydrolase" ;
up:shortName 'dUTPase' ;
rdf:type up:Structured_Name .
?name1 up:fullName 'dUTP pyrophosphatase' ;
rdf:type up:Structured_Name .
?gene2 skos:prefLabel 'DUT' .
?annotation3 a up:Function_Annotation ;
rdfs:comment 'Involved in nucleotide metabolism: produces dUMP, the immediate precursor of thymidine nucleotides and decreases the intracellular concentration of dUTP to avoid uracil incorporation into viral DNA.' .
?annotation4 up:activity ?activity5 ;
rdf:type up:Catalytic_Activity_Annotation .
?activity5 up:catalyticActivity ;
up:enzymeClass .
?annotation6 up:cofactor chebi:18420 ;
rdf:type up:Cofactor_Annotation .
?annotation7 a up:Similarity_Annotation ;
rdfs:comment 'Belongs to the dUTPase family.' .
?pfs8 up:annotation ?annotation9 .
?annotation9 faldo:begin ?pfsb10 ;
faldo:end ?pfse11 ;
up:ligand ?ligand12 ;
rdf:type up:Binding_Site_Annotation .
?pfsb10 faldo:position ?thisPositionOn14 ;
rdf:type faldo:ExactPosition .
?pfse11 faldo:position ?thisPositionOn15 ;
rdf:type faldo:ExactPosition .
?ligand12 rdfs:subClassOf ?molecule13 .
?molecule13 rdfs:label 'substrate' .
?pfs16 up:annotation ?annotation17 .
?annotation17 faldo:begin ?pfsb18 ;
faldo:end ?pfse19 ;
up:ligand ?ligand20 ;
rdf:type up:Binding_Site_Annotation .
?pfsb18 faldo:position ?thisPositionOn22 ;
rdf:type faldo:ExactPosition .
?pfse19 faldo:position ?thisPositionOn23 ;
rdf:type faldo:ExactPosition .
?ligand20 rdfs:subClassOf ?molecule21 .
?molecule21 rdfs:label 'substrate' .
_:904859 a rdf:Statement ;
up:attribution _:904843 ;
rdf:subject ?this ;
rdf:predicate up:recommendedName ;
rdf:object ?name0 .
_:904860 a rdf:Statement ;
up:attribution _:904844 ;
rdf:subject ?this ;
rdf:predicate up:alternativeName ;
rdf:object ?name1 .
_:904861 a rdf:Statement ;
up:attribution _:904845 ;
rdf:subject ?gene2 ;
rdf:predicate up:encodedBy ;
rdf:object ?gene2 .
_:904862 a rdf:Statement ;
up:attribution _:904846 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation3 .
_:904863 a rdf:Statement ;
up:attribution _:904847 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation4 .
_:904864 a rdf:Statement ;
up:attribution _:904848 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation6 .
_:904865 a rdf:Statement ;
up:attribution _:904849 ;
rdf:subject ?this ;
rdf:predicate up:annotation ;
rdf:object ?annotation7 .
_:904866 a rdf:Statement ;
up:attribution _:904850 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:378 .
_:904867 a rdf:Statement ;
up:attribution _:904851 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:460 .
_:904868 a rdf:Statement ;
up:attribution _:904852 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:479 .
_:904869 a rdf:Statement ;
up:attribution _:904853 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object keyword:546 .
_:904870 a rdf:Statement ;
up:attribution _:904854 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0004170 .
_:904871 a rdf:Statement ;
up:attribution _:904855 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0046872 .
_:904872 a rdf:Statement ;
up:attribution _:904856 ;
rdf:subject ?this ;
rdf:predicate up:classifiedWith ;
rdf:object GO:0046080 .
_:904873 a rdf:Statement ;
up:source unirule:MF_04031 ;
rdf:subject ?pfs8 ;
rdf:predicate up:annotation ;
rdf:object ?annotation9 .
_:904874 a rdf:Statement ;
up:attribution _:904857 ;
rdf:subject ?pfs8 ;
rdf:predicate up:annotation ;
rdf:object ?annotation9 .
_:904875 a rdf:Statement ;
up:source unirule:MF_04031 ;
rdf:subject ?pfs16 ;
rdf:predicate up:annotation ;
rdf:object ?annotation17 .
_:904876 a rdf:Statement ;
up:attribution _:904858 ;
rdf:subject ?pfs16 ;
rdf:predicate up:annotation ;
rdf:object ?annotation17 .
}
WHERE {
#baseURI: http://purl.uniprot.org/unirule/MF_04031
#Rule MF_04031 Created by:? on:2016-05-09 Modified by:Edouard de Castro on:2024-09-02
?this up:organism ?thisOrganism ;
rdfs:seeAlso signature:MF_04031 .
?thisOrganism rdfs:subClassOf+ taxon:10292 .
BIND(URI(CONCAT(STR(?this), '#MF_04031a0')) AS ?name0) .
BIND(URI(CONCAT(STR(?this), '#MF_04031a1')) AS ?name1) .
BIND(URI(CONCAT(STR(?this), '#MF_04031a3')) AS ?annotation3) .
BIND(URI(CONCAT(STR(?this), '#MF_04031a4')) AS ?annotation4) .
BIND(URI(CONCAT(STR(?this), '#MF_04031a6')) AS ?annotation6) .
BIND(URI(CONCAT(STR(?this), '#MF_04031a7')) AS ?annotation7) .
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch28 faldo:location ?templateMotifSequenceMatchRegionP1023429 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP1023431 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarP10234MF_0403124 .
?templateMotifSequenceMatchRegionP1023429 faldo:begin ?templateMotifSequenceMatchBeginP1023430 .
?templateMotifSequenceMatchBeginP1023430 faldo:position ?templateMotifSequenceMatchBeginPositionP1023425 ;
faldo:reference isoform:P10234-1 .
?templateMotifSequenceProfileAlignmentOperationP1023431 edam:has_input signature:MF_04031 ;
rdf:type edam:operation_0300 .
?targetMotifMatch32 faldo:location ?targetMotifMatchRegionMatch33 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0403135 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarP10234MF_0403126 .
?targetMotifMatchRegionMatch33 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0403134 .
?targetMotifMatchRegionMatchBeginMF_0403134 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0403127 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0403135 edam:has_input signature:MF_04031 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP10234MF_0403124, 1, (STRLEN(?templateMotifCigarP10234MF_0403124) - STRLEN(REPLACE(?templateMotifCigarP10234MF_0403124, CONCAT('^(?:-*[^-]){', STR(((260 - ?templateMotifSequenceMatchBeginPositionP1023425) + 1)), '}'), '')))), '[a-z]', '')) AS ?step136) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP10234MF_0403126, 1, (STRLEN(?targetMotifMatchCigarP10234MF_0403126) - STRLEN(REPLACE(?targetMotifMatchCigarP10234MF_0403126, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step136), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP10234MF_0403126, 1, (STRLEN(?targetMotifMatchCigarP10234MF_0403126) - STRLEN(REPLACE(?targetMotifMatchCigarP10234MF_0403126, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step136), '}'), '')))), '[^-]', ''))) AS ?step237) .
BIND(((?step237 + ?targetMotifMatchRegionMatchBeginPositionMF_0403127) - 1) AS ?thisPositionOn14) .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP10234MF_0403124, 1, (STRLEN(?templateMotifCigarP10234MF_0403124) - STRLEN(REPLACE(?templateMotifCigarP10234MF_0403124, CONCAT('^(?:-*[^-]){', STR(((262 - ?templateMotifSequenceMatchBeginPositionP1023425) + 1)), '}'), '')))), '[a-z]', '')) AS ?step138) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP10234MF_0403126, 1, (STRLEN(?targetMotifMatchCigarP10234MF_0403126) - STRLEN(REPLACE(?targetMotifMatchCigarP10234MF_0403126, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step138), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP10234MF_0403126, 1, (STRLEN(?targetMotifMatchCigarP10234MF_0403126) - STRLEN(REPLACE(?targetMotifMatchCigarP10234MF_0403126, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step138), '}'), '')))), '[^-]', ''))) AS ?step239) .
BIND(((?step239 + ?targetMotifMatchRegionMatchBeginPositionMF_0403127) - 1) AS ?thisPositionOn15) .
BIND(?this AS ?pfs1t40) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn14))) AS ?pfsb10) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn15))) AS ?pfse11) .
FILTER (REGEX('RS[SG]', SUBSTR(?thisSequenceValue, ?thisPositionOn14, (?thisPositionOn15 - ?thisPositionOn14)))) .
BIND(URI(CONCAT(STR(?this), '#MF_04031a9')) AS ?annotation9) .
BIND(?this AS ?pfs8) .
}
OPTIONAL {
?this up:sequence ?thisSequence .
?thisSequence rdf:value ?thisSequenceValue .
?templateMotifMatch45 faldo:location ?templateMotifSequenceMatchRegionP1023446 ;
edam:is_output_of ?templateMotifSequenceProfileAlignmentOperationP1023448 ;
rdf:type edam:data_0869 ;
rdf:value ?templateMotifCigarP10234MF_0403141 .
?templateMotifSequenceMatchRegionP1023446 faldo:begin ?templateMotifSequenceMatchBeginP1023447 .
?templateMotifSequenceMatchBeginP1023447 faldo:position ?templateMotifSequenceMatchBeginPositionP1023442 ;
faldo:reference isoform:P10234-1 .
?templateMotifSequenceProfileAlignmentOperationP1023448 edam:has_input signature:MF_04031 ;
rdf:type edam:operation_0300 .
?targetMotifMatch49 faldo:location ?targetMotifMatchRegionMatch50 ;
edam:is_output_of ?targetMotifSequenceAlignmentOperationMF_0403152 ;
rdf:type edam:data_0869 ;
rdf:value ?targetMotifMatchCigarP10234MF_0403143 .
?targetMotifMatchRegionMatch50 faldo:begin ?targetMotifMatchRegionMatchBeginMF_0403151 .
?targetMotifMatchRegionMatchBeginMF_0403151 faldo:position ?targetMotifMatchRegionMatchBeginPositionMF_0403144 ;
faldo:reference ?thisSequence .
?targetMotifSequenceAlignmentOperationMF_0403152 edam:has_input signature:MF_04031 ;
rdf:type edam:operation_0300 .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP10234MF_0403141, 1, (STRLEN(?templateMotifCigarP10234MF_0403141) - STRLEN(REPLACE(?templateMotifCigarP10234MF_0403141, CONCAT('^(?:-*[^-]){', STR(((366 - ?templateMotifSequenceMatchBeginPositionP1023442) + 1)), '}'), '')))), '[a-z]', '')) AS ?step153) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP10234MF_0403143, 1, (STRLEN(?targetMotifMatchCigarP10234MF_0403143) - STRLEN(REPLACE(?targetMotifMatchCigarP10234MF_0403143, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step153), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP10234MF_0403143, 1, (STRLEN(?targetMotifMatchCigarP10234MF_0403143) - STRLEN(REPLACE(?targetMotifMatchCigarP10234MF_0403143, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step153), '}'), '')))), '[^-]', ''))) AS ?step254) .
BIND(((?step254 + ?targetMotifMatchRegionMatchBeginPositionMF_0403144) - 1) AS ?thisPositionOn22) .
BIND(STRLEN(REPLACE(SUBSTR(?templateMotifCigarP10234MF_0403141, 1, (STRLEN(?templateMotifCigarP10234MF_0403141) - STRLEN(REPLACE(?templateMotifCigarP10234MF_0403141, CONCAT('^(?:-*[^-]){', STR(((367 - ?templateMotifSequenceMatchBeginPositionP1023442) + 1)), '}'), '')))), '[a-z]', '')) AS ?step155) .
BIND((STRLEN(SUBSTR(?targetMotifMatchCigarP10234MF_0403143, 1, (STRLEN(?targetMotifMatchCigarP10234MF_0403143) - STRLEN(REPLACE(?targetMotifMatchCigarP10234MF_0403143, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step155), '}'), ''))))) - STRLEN(REPLACE(SUBSTR(?targetMotifMatchCigarP10234MF_0403143, 1, (STRLEN(?targetMotifMatchCigarP10234MF_0403143) - STRLEN(REPLACE(?targetMotifMatchCigarP10234MF_0403143, CONCAT('^(?:[a-z]*(?:[A-Z]|-)){', STR(?step155), '}'), '')))), '[^-]', ''))) AS ?step256) .
BIND(((?step256 + ?targetMotifMatchRegionMatchBeginPositionMF_0403144) - 1) AS ?thisPositionOn23) .
BIND(?this AS ?pfs1t57) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn22))) AS ?pfsb18) .
BIND(URI(CONCAT(STR(?thisSequence), '#position', STR(?thisPositionOn23))) AS ?pfse19) .
FILTER ((SUBSTR(?thisSequenceValue, ?thisPositionOn22, (?thisPositionOn23 - ?thisPositionOn22)) = 'FG')) .
BIND(URI(CONCAT(STR(?this), '#MF_04031a17')) AS ?annotation17) .
BIND(?this AS ?pfs16) .
}
}
"xsd:string |