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HAMAP: Actinobacillus pleuropneumoniae serotype 7 (strain AP76) complete proteome
General information

Species:  Actinobacillus pleuropneumoniae serotype 7 (strain AP76)
Species code: ACTP7
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Actinobacillus (TaxID: 537457) [NEWT/ NCBI]
Description: Actinobacillus pleuropneumoniae, a Gram-negative, non-motile, facultatively anaerobic Pasteurellaceae, causes porcine pleuropneumonia, a highly contagious disease for which there is no effective vaccine. There are least twelve different serotypes, some of which produce no disease but others cause severe disease. Serotypes vary in different countries. Types 1, 5, 9, 11 and 12 are usually highly virulent and strains 3 and 6 are mild. The bacterium is carried in the tonsils and upper respiratory tract. It is transmitted short distances by droplet infection and only survives outside the pig for a few days.

Strain AP76 was isolated from a diseased pig lung in Canada. It is serotype 7 and is a strain in which spontaneous chromosomal deletions have been shown to occur. It encodes insertion elements that have been shown to interfere with detection of infected vs. vaccinated animals as it inserts into serological antigens used to detect infection.
Properties: Presence of flagella: No
Human pathogen: No
Interaction: Animal pathogen in Mammalia
Number of membranes: 2
Number of inteins:0
Statistics: Number of ACTP7 entries in the UniProt Knowledgebase: 2113 (381 in UniProtKB/Swiss-Prot + 1732 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    AP76
Genome structure:
• Chromosome EMBL accession number CP001091 (circular; 2,331,981 bp) (download entry)
• Plasmid APP7_A EMBL accession number CP001094 (circular; 5,685 bp) (download entry)
• Plasmid ABB7_B EMBL accession number CP001093 (circular; 4,236 bp) (download entry)
• Plasmid APP7_C EMBL accession number CP001092 (circular; 3,533 bp) (download entry)
Reference(s):
[1] Linke B., Buettner F., Martinez-Arias R., Goesmann A., Baltes N., Tegetmeyer H., Singh M., Gerlach G.F. ;
"Genome and proteome analysis of A. pleuropneumoniae serotype 7.";
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
Web links:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=29909
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Aple_AP76
 EBI Proteome Analysis page



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