Home | Contact

Species code:	BACHK
Taxonomy:	Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus; Bacillus cereus group (TaxID: 281309) [NEWT/ NCBI]
Description:	Bacillus thuringiensis is a Gram-positive, spore-forming bacterium that belongs to the B.cereus group along with Bacillus anthracis and Bacillus cereus. Bacillus thuringiensis is an insect pathogen that is widely used as a biopesticide in commercial agriculture due to its various endogenous crystal proteins and spores. When insects ingest toxin crystals, the alkaline pH of their digestive tract activates the toxin. Cry inserts into the insect gut cell membrane, forming a pore. The pore results cell lysis and eventual death of the insect. Infection of humans is unusual. Bacillus thuringiensis 97-27 was originally isolated from a case of severe human tissue necrosis superinfection. The apparent pathogenic properties of B. thuringiensis 97-27 are very unusual for B. thuringiensis; unlike most B. thuringiensis isolates, this isolate is very closely related to B. anthracis based on phylogenetic analysis.
Properties:	Presence of flagella: Yes Human pathogen: No Interaction: Animal pathogen in Insecta Number of membranes: 1 Number of inteins:0
Statistics:	Number of BACHK entries in the UniProt Knowledgebase: 567 (567 in UniProtKB/Swiss-Prot + 0 in UniProtKB/TrEMBL)

Genome structure:	• Chromosome EMBL accession number AE017355 (circular; 5,237,682 bp) (download entry) • Plasmid pBT9727 EMBL accession number CP000047 (circular; 77,112 bp) (download entry)
Reference(s):	[1] PubMed=16621833; [ NCBI , EBI , Israel , Japan ] Han C.S., Xie G., Challacombe J.F., Altherr M.R., Bhotika S.S., Bruce D., Campbell C.S., Campbell M.L., Chen J., Chertkov O., Cleland C., Dimitrijevic M., Doggett N.A., Fawcett J.J., Glavina T., Goodwin L.A., Hill K.K., Hitchcock P., Jackson P.J., Keim P., Kewalramani A.R., Longmire J., Lucas S., Malfatti S., McMurry K., Meincke L.J., Misra M., Moseman B.L., Mundt M., Munk A.C., Okinaka R.T., Parson-Quintana B., Reilly L.P., Richardson P., Robinson D.L., Rubin E., Saunders E., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Ticknor L.O., Wills P.L., Brettin T.S., Gilna P. ; "Pathogenomic sequence analysis of Bacillus cereus and Bacillus thuringiensis isolates closely related to Bacillus anthracis."; J. Bacteriol. 188:3382-3390(2006).
Web links:	Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid281309%5Borgn%5D Genome Atlas: http://www.cbs.dtu.dk/services/gwBrowser/project.php?pid=10877 GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Bthu_KONKUKIAN JVCI CMR: http://cmr.jcvi.org/tigr-scripts/CMR/GenomePage.cgi?database=ntbt02 Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Bacillus_thuringiensis.html Pathema: http://pathema.jcvi.org/cgi-bin/Bacillus/shared/GenomePage.cgi?org=ntbt02 PEDANT: http://pedant.gsf.de/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p10877_Bac_thuri  EBI Proteome Analysis page

• Perform a BLAST search against all proteins from this proteome
  
  
• Download all UniProt Knowledgebase entries of this proteome
  • in UniProt Knowledgebase format
  • in FASTA format
  
  
• Retrieve set of characterized or identified proteins for this proteome
  
  
• Retrieve set of proteins with 3D structure for this proteome

Swiss Institute of Bioinformatics | Disclaimer