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HAMAP: Borrelia hermsii (strain DAH) complete proteome
General information

Species:  Borrelia hermsii (strain DAH)
Species code: BORHD
Taxonomy: Bacteria; Spirochaetes; Spirochaetales; Spirochaetaceae; Borrelia (TaxID: 314723) [NEWT/ NCBI]
Description: Relapsing fever (RF) is a disease caused by several spirochetes of the genus Borrelia. Relapsing fever borrelioses are characterized by recurrent febrile episodes and spirochetemia. There are 2 forms; louse-borne relapsing fever (also known as urban or epidemic RF) is caused by Borrelia recurrentis, and is transmitted by the body louse Pediculus humanus humanus. It currently known in Ethiopia. Endemic tick-borne relapsing fever (TBRF) is a zoonotic disease transmitted worldwide by softbody ticks of the genus Ornithodoros. It is caused by at least 15 distinct Borrelia species throughout the world, including Borrelia hermsii and Borrelia turicatae, carried by the ticks Ornithodoros hermsii and O.turicatae respectively (modified from PubMed 16965346). B.hermsii lives in chipmunks and tree squirrels in high-altitude forests of California, Arizona, Nevada, Colorado, Oregon, Idaho, Washington, and British Columbia. B.hermsii evades the mammalian immune system by periodically switching expression among members of two multigene families that encode immunogenic, antigenically distinct outer surface proteins (modified from PubMed 9453591).
Properties: Presence of flagella: Yes
Human pathogen: Yes
Interaction: Animal pathogen in Mammalia
Number of membranes: 2
Number of inteins:0
Statistics: Number of BORHD entries in the UniProt Knowledgebase: 819 (126 in UniProtKB/Swiss-Prot + 693 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    DAH
Genome structure:
Chromosome EMBL accession number CP000048 (linear; 922,307 bp) (download entry)
Reference(s):
[1] Porcella S.F., Raffel S.J., Schrumpf M.E., Montgomery B., Smith T., Schwan T.G. ;
"The genome sequence of Borrelia hermsii and Borrelia turicatae: comparative analysis of two agents of endemic N. America relapsing fever.";
Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
Web links:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=29637
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Bher_DAH
PEDANT: http://pedant.gsf.de/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p29637_Bor_herms
 EBI Proteome Analysis page



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