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HAMAP: Escherichia coli O8 (strain IAI1) complete proteome
General information

Species:  Escherichia coli O8 (strain IAI1)
Species code: ECO8A
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia (TaxID: 585034) [NEWT/ NCBI]
Description: Escherichia coli is a Gram-negative straight rod, which either uses peritrichous flagella for mobility or is nonmotile. It is a facultatively anaerobic chemoorganotroph capable of both respiratory and fermentative metabolism. E.coli serves a useful function in the body by suppressing the growth of harmful bacterial species and by synthesizing appreciable amounts of vitamins. It is an important component of the biosphere. It colonizes the lower gut of animals and survives when released to the natural environment, allowing widespread dissemination to new hosts. Pathogenic E.coli strains are responsible for infection of the enteric, urinary, pulmonary and nervous systems. Comparison of 20 E.coli/Shigella strains shows the core genome to be about 2000 genes while the pan-genome has over 18,000 genes. There are multiple, striking integration hotspots that are conserved across the genomes, corresponding to regions of abundant and parallel insertions and deletions of genetic material.

Strain IAI1 is a human commensal strain isolated from the faeces of a healthy French man in the 1980s. It is serotype O8, phylogenetic group B1. It does not encode the main extraintestinal virulence genes.
Properties: Presence of flagella: Yes
Human pathogen: No
Interaction: Animal commensal in Mammalia
Number of membranes: 2
Number of inteins:0
Statistics: Number of ECO8A entries in the UniProt Knowledgebase: 4330 (761 in UniProtKB/Swiss-Prot + 3569 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    IAI1
Genome structure:
Chromosome EMBL accession number CU928160 (circular; 4,700,560 bp) (download entry)
Reference(s):
[1] PubMed=19165319; [ NCBI , EBI , Israel , Japan ]
Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P., Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H., Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E., Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C., Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S., Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J., Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E. ;
"Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths.";
PLoS Genet. 5:E1000344-E1000344(2009).
Web links:
Official genome site(s):
http://www.genoscope.cns.fr/spip/-Escherichia-fergusonii-coli-.html
Other web sites:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?db=genomeprj&cmd=Retrieve&dopt=Overview&list_uids=33373
Genome Atlas: http://www.cbs.dtu.dk/services/gwBrowser/project.php?pid=33373
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Ecol_IAI1
 EBI Proteome Analysis page



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