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HAMAP: Fibrobacter succinogenes (strain ATCC 19169 / S85) complete proteome
General information

Species:  Fibrobacter succinogenes (strain ATCC 19169 / S85)
Species code: FIBSS
Taxonomy: Bacteria; Fibrobacteres; Fibrobacterales; Fibrobacteraceae; Fibrobacter (TaxID: 59374) [NEWT/ NCBI]
Description: Fibrobacter succinogenes (strain ATCC 19169 / S85) is an anaerobic, cellulolytic Gram-negative bacterium. It is one of the three most predominant cellulolytic organisms in the rumen. F. succinogenes is highly specialized for cellulose degradation, and is only capable of utilizing cellulose and cellulolytic degradation products as carbon sources. Access to cellulose is a rate-liming step in degradation, and F. succinogenes has devised a number of mechanisms for improving access to this insoluble substrate, one of which is the production of surface-localized cellulases. The active enzymes are cell wall associated, but the presence of cellulosomes, large multiprotein cellulase complexes, has not been detected in this organism. Adherence is another method used to promote cellulose degradation, and this organism produces an extracellular matrix of glycoprotein glycocalyx which allows attachment to insoluble cellulose. In addition, the glycocalyx protects against protozoan attack of the bacterium as well as protease attack of the cellulase enzymes. Increasing cellulose degradation is an important goal in industrial processes. (Adaptated from: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=32617).
Fibrobacter succinogenes (strain ATCC 19169 / S85) is an anaerobic, cellulolytic Gram-negative bacterium. It is one of the three most predominant cellulolytic organisms in the rumen. F. succinogenes is highly specialized for cellulose degradation, and is only capable of utilizing cellulose and cellulolytic degradation products as carbon sources. Access to cellulose is a rate-liming step in degradation, and F. succinogenes has devised a number of mechanisms for improving access to this insoluble substrate, one of which is the production of surface-localized cellulases. The active enzymes are cell wall associated, but the presence of cellulosomes, large multiprotein cellulase complexes, has not been detected in this organism. Adherence is another method used to promote cellulose degradation, and this organism produces an extracellular matrix of glycoprotein glycocalyx which allows attachment to insoluble cellulose. In addition, the glycocalyx protects against protozoan attack of the bacterium as well as protease attack of the cellulase enzymes. Increasing cellulose degradation is an important goal in industrial processes. (Adaptated from: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=32617).
Fibrobacter succinogenes (strain ATCC 19169 / S85) is an anaerobic, cellulolytic Gram-negative bacterium. It is one of the three most predominant cellulolytic organisms in the rumen. F. succinogenes is highly specialized for cellulose degradation, and is only capable of utilizing cellulose and cellulolytic degradation products as carbon sources. Access to cellulose is a rate-liming step in degradation, and F. succinogenes has devised a number of mechanisms for improving access to this insoluble substrate, one of which is the production of surface-localized cellulases. The active enzymes are cell wall associated, but the presence of cellulosomes, large multiprotein cellulase complexes, has not been detected in this organism. Adherence is another method used to promote cellulose degradation, and this organism produces an extracellular matrix of glycoprotein glycocalyx which allows attachment to insoluble cellulose. In addition, the glycocalyx protects against protozoan attack of the bacterium as well as protease attack of the cellulase enzymes. Increasing cellulose degradation is an important goal in industrial processes. (Adaptated from: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=32617).
Fibrobacter succinogenes (strain ATCC 19169 / S85) is an anaerobic, cellulolytic Gram-negative bacterium. It is one of the three most predominant cellulolytic organisms in the rumen. F. succinogenes is highly specialized for cellulose degradation, and is only capable of utilizing cellulose and cellulolytic degradation products as carbon sources. Access to cellulose is a rate-liming step in degradation, and F. succinogenes has devised a number of mechanisms for improving access to this insoluble substrate, one of which is the production of surface-localized cellulases. The active enzymes are cell wall associated, but the presence of cellulosomes, large multiprotein cellulase complexes, has not been detected in this organism. Adherence is another method used to promote cellulose degradation, and this organism produces an extracellular matrix of glycoprotein glycocalyx which allows attachment to insoluble cellulose. In addition, the glycocalyx protects against protozoan attack of the bacterium as well as protease attack of the cellulase enzymes. Increasing cellulose degradation is an important goal in industrial processes. (Adaptated from: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=32617).
Properties: Presence of flagella: No
Human pathogen: No
Interaction: No
Number of membranes: 2
Number of inteins:0
Statistics: Number of FIBSS entries in the UniProt Knowledgebase: 3796 (9 in UniProtKB/Swiss-Prot + 3787 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    ATCC 19169 / S85
Genome structure:
Chromosome EMBL accession number CP001792 (circular; 3,842,635 bp) (download entry)
Reference(s):
[1] Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Weimer P.J., Stevenson D.M., Boyum J., Brumm P.I., Mead D. ;
"Complete sequence of Fibrobacter succinogenes subsp. succinogenes S85.";
Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
Web links:
Official genome site(s):
http://genome.jgi-psf.org/fibsu/fibsu.home.html
Other web sites:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=32617
Genome Atlas: http://www.cbs.dtu.dk/services/gwBrowser/precalc/project.php?pid=41169
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Fsuc_S85
GOLD: http://genomesonline.org/cgi-bin/GOLD/bin/GOLDCards.cgi?goldstamp=Gc01125
img/geba: http://img.jgi.doe.gov/cgi-bin/geba/main.cgi?section=TaxonDetail&page=taxonDetail&taxon_oid=646311927
 EBI Proteome Analysis page

Strain:    ATCC 19169 / S85
Genome structure:
Chromosome EMBL accession number CP002158 (circular; 3,843,004 bp) (download entry)
Reference(s):
[1] Durkin A.S., Nelson K.E., Morrison M., Forsberg C.W., Wilson D.B., Russell J.B., Cann I.K.O., Mackie R.I., White B.A. ;
"Complete sequence of Fibrobacter succinogenes subsp. succinogenes S85.";
Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
Web links:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/genomeprj?Db=genomeprj&cmd=ShowDetailView&TermToSearch=47
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Fsuc_S85_JCVI
GOLD: http://genomesonline.org/cgi-bin/GOLD/bin/GOLDCards.cgi?goldstamp=Gc01427
 EBI Proteome Analysis page



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