HAMAP: Gardnerella vaginalis (strain 409-05) complete proteome

General information

Species:  Gardnerella vaginalis (strain 409-05)
Species code: GARV4
Taxonomy: Bacteria; Actinobacteria; Actinobacteridae; Bifidobacteriales; Bifidobacteriaceae; Gardnerella (TaxID: 553190) [NEWT/ NCBI]
Description: Gardnerella vaginalis (strain 409-05) is a facultative anaerobic Gram-variable bacterium. It is the most prevalent sexually transmitted organism and is associated with bacterial vaginosis (BV) in which the normal lactobacilli microbiota is replaced by relatively high concentrations of other bacteria, especially G. vaginalis. It reflects a complex alteration of the vaginal microbiota, normally in the absence of inflammatory response. It generally leads to the presence of intense discharges in the absence of itching, burning sensations or urinary symptoms. G. vaginalis was found to be a risk factor for the acquisition of human immunodeficiency virus (HIV), in which stimulation of HIV expression by G. vaginalis was demonstrated. This bacterium is also associated with bacteraemia, urinary track infections, and neonatal meningitis. (Adaptated from PMID: 20221621).
Properties: Presence of flagella: No
Human pathogen: Yes
Interaction: Animal pathogen in Mammalia
Number of membranes: 1
Statistics: Number of GARV4 entries in UniProtKB: 1257 (0 in UniProtKB/Swiss-Prot + 1257 in UniProtKB/TrEMBL)

Genome(s) sequenced

Strain:    409-05
Genome structure:
Chromosome EMBL accession number CP001849 (circular; 1,617,545 bp) (download entry)
Reference(s):
[1] Pubmed=20865041;
Yeoman C.J., Yildirim S., Thomas S.M., Durkin A.S., Torralba M., Sutton G., Buhay C.J., Ding Y., Dugan-Rocha S.P., Muzny D.M., Qin X., Gibbs R.A., Leigh S.R., Stumpf R., White B.A., Highlander S.K., Nelson K.E., Wilson B.A. ;
"Comparative genomics of Gardnerella vaginalis strains reveals substantial differences in metabolic and virulence potential.";
PLoS ONE 5:E12411-E12411(2010).
Web links:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=37367
GIB (DDBJ): http://gtps.ddbj.nig.ac.jp/single/index.php?spid=Gvag_40905
Unofficial: http://hmp.jcvi.org/jumpstart/hmp021/index.shtml


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