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HAMAP: Haemophilus somnus (strain 129Pt) (Histophilus somni (strain 129Pt)) complete proteome
General information

Species:  Haemophilus somnus (strain 129Pt) (Histophilus somni (strain 129Pt))
Species code: HAES1
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Histophilus (TaxID: 205914) [NEWT/ NCBI]
Description: Haemophilus somnus is the cause of a variety of systemic diseases in cattle, including thrombotic-meningoencephalitis, pneumonia, abortion and other reproductive diseases, arthritis, myocarditis, and septicemia. Diseases due to H. somnus account for millions of dollars in losses to the cattle industry, and are particularly prevalent in feedlots; additionally this agent may also affect dairy cattle. It may be the most economically important pathogen of feedlot cattle.

H.somnus 129Pt is an avirulent commensal strain. Extensive comparisons between 3 available Haemophilus were performed (H.somnus 129Pt, H.influenzae Rd and H.ducreyi 35000HP). It encodes the shikimate pathway for chorismate biosynthesis and all components of the ubiquinone and menaquinone synthesis pathways, as well as genes involved in lipooligosaccharide biosynthesis, carbohydrate uptake and metabolism, cation transport, amino acid metabolism and so on, that may be important to its ecological niche.
Properties: Presence of flagella: No
Human pathogen: No
Interaction: Animal commensal in Mammalia; Animal pathogen in Mammalia; Avirulent strain
Number of membranes: 2
Number of inteins:0
Statistics: Number of HAES1 entries in the UniProt Knowledgebase: 1793 (401 in UniProtKB/Swiss-Prot + 1392 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    129Pt
Genome structure:
• Chromosome EMBL accession number CP000436 (circular; 2,007,700 bp) (download entry)
• Plasmid pHS129 EMBL accession number CP000019 (circular; 5,178 bp) (download entry)
Reference(s):
[1] PubMed=17172329; [ NCBI , EBI , Israel , Japan ]
Challacombe J.F., Duncan A.J., Brettin T.S., Bruce D., Chertkov O., Detter J.C., Han C.S., Misra M., Richardson P., Tapia R., Thayer N., Xie G., Inzana T.J. ;
"Complete genome sequence of Haemophilus somnus (Histophilus somni) strain 129Pt and comparison to Haemophilus ducreyi 35000HP and Haemophilus influenzae Rd.";
J. Bacteriol. 189:1890-1898(2007).
Web links:
Official genome site(s):
http://genome.jgi-psf.org/finished_microbes/haeso/haeso.home.html
Other web sites:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid205914%5Borgn%5D
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Hsom_129PT
NMPDR: http://www.nmpdr.org/FIG/wiki/rest.cgi/NmpdrPlugin/SeedViewer?pattern=205914.1;page=SearchResult
PEDANT: http://pedant.gsf.de/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p322_Hae_somnu
 EBI Proteome Analysis page



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