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HAMAP: Helicobacter pylori (strain P12) complete proteome
General information

Species:  Helicobacter pylori (strain P12)
Species code: HELP2
Taxonomy: Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; Helicobacteraceae; Helicobacter (TaxID: 570508) [NEWT/ NCBI]
Description: Micro-aerophilic, Gram-negative, slow-growing, spiral-shaped and flagellated organism. H.pylori is probably the most common cause of chronic bacterial infection of humans, present in almost half of the world population. The presence of the bacterium in the gastric mucosa is associated with chronic active gastritis and is implicated in more severe gastric diseases, including chronic atrophic gastritis, peptic ulceration and mucosa-associated lymphoid tissue lymphomas.

H. pylori P12 is a clinical isolate obtained from a German patient with duodenal ulcer in 1994.
Properties: Presence of flagella: Yes
Human pathogen: Yes
Interaction: Animal commensal in Mammalia; Animal pathogen in Mammalia
Number of membranes: 2
Number of inteins:0
Statistics: Number of HELP2 entries in the UniProt Knowledgebase: 1572 (257 in UniProtKB/Swiss-Prot + 1315 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    P12
Genome structure:
• Chromosome EMBL accession number CP001217 (circular; 1,673,813 bp) (download entry)
• Plasmid HPP12 EMBL accession number CP001218 (circular; 10,225 bp) (download entry)
Reference(s):
[1] Fischer W., Windhager L., Karnholz A., Zeiller M., Zimmer R., Haas R. ;
"The complete genome sequence of Helicobacter pylori strain P12.";
Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
Web links:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=32291
Genome Atlas: http://www.cbs.dtu.dk/services/gwBrowser/project.php?pid=32291
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Hpyl_P12
 EBI Proteome Analysis page



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