Home Proteomes Families Hamap-Scan Documents Downloads Links
HAMAP: Helicobacter pylori (strain Shi470) complete proteome
General information

Species:  Helicobacter pylori (strain Shi470)
Species code: HELPS
Taxonomy: Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; Helicobacteraceae; Helicobacter (TaxID: 512562) [NEWT/ NCBI]
Description: Micro-aerophilic, Gram-negative, slow-growing, spiral-shaped and flagellated organism. H.pylori is probably the most common cause of chronic bacterial infection of humans, present in almost half of the world population. The presence of the bacterium in the gastric mucosa is associated with chronic active gastritis and is implicated in more severe gastric diseases, including chronic atrophic gastritis, peptic ulceration and mucosa-associated lymphoid tissue lymphomas.

Helicobacter pylori Shi470 is a clinical isolate from the gastric antrum of an Amerindian resident of the remote Amazonian village of Shimaa, in Peru. Shimaa village strains such as Shi470 are more closely related to strains from East Asia than other geographic regions, and are postulated to represent the strains of Native Americans before European conquest.
Properties: Presence of flagella: Yes
Human pathogen: Yes
Interaction: Animal pathogen in Mammalia
Number of membranes: 2
Number of inteins:0
Statistics: Number of HELPS entries in the UniProt Knowledgebase: 1564 (261 in UniProtKB/Swiss-Prot + 1303 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    Shi470
Genome structure:
Chromosome EMBL accession number CP001072 (circular; 1,608,548 bp) (download entry)
Reference(s):
[1] Kersulyte D., Kalia A., Gilman R.H., Berg D.E. ;
"Genome sequence of Helicobacter pylori from the remote Amazon: traces of Asian ancestry of the first Americans.";
Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
Web links:
Official genome site(s):
http://www.microbiology.wustl.edu/dept/fac/berg.html
http://ddrcc.wustl.edu/FACULTY/Berg.html
Other web sites:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=29045
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Hpyl_Shi470
 EBI Proteome Analysis page



Tools