HAMAP: Lactobacillus fermentum (strain NBRC 3956 / LMG 18251) complete proteome
General information

Species:  Lactobacillus fermentum (strain NBRC 3956 / LMG 18251)
Species code: LACF3
Taxonomy: Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus (TaxID: 334390) [NEWT/ NCBI]
Description: Lactobacilli are normal inhabitants of the gastrointestinal tract of man and animals where they are widely considered to exert a number of beneficial roles including immunomodulation, interference with enteric pathogens, and maintenance of a healthy intestinal microflora. Historically, probiotic roles have been ascribed primarily to Lactobacillus acidophilus. The genus Lactobacillus presently comprises more than 50 recognized species of non pathogenic bacteria which in addition to their probiotic effects are useful to human as indispensable agents for the fermentation of foods and feed.

L.fermentum IFO 3956, isolated from fermented plant material, is an obligate heterofermentative organism, producing CO2, ethanol, acetate, and lactate from metabolism of glucose. To do so it probably uses the pentose phosphate pathway. Unlike the closely related Lactobacillus reuteri JCM 1112, it does not make cobalamin or the antimicrobial compound reuterin (adapted from PubMed 18487258).
Properties: Presence of flagella: No
Human pathogen: No
Interaction: No
Number of membranes: 1
Number of inteins:0
Statistics: Number of LACF3 entries in the UniProt Knowledgebase: 1818 (225 in UniProtKB/Swiss-Prot + 1593 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    NBRC 3956 / LMG 18251
Genome structure:
Chromosome EMBL accession number AP008937 (circular; 2,098,685 bp) (download entry)
Reference(s):
[1] PubMed=18487258; [ NCBI , EBI , Israel , Japan ]
Morita H., Toh H., Fukuda S., Horikawa H., Oshima K., Suzuki T., Murakami M., Hisamatsu S., Kato Y., Takizawa T., Fukuoka H., Yoshimura T., Itoh K., O'Sullivan D.J., McKay L.L., Ohno H., Kikuchi J., Masaoka T., Hattori M. ;
"Comparative genome analysis of Lactobacillus reuteri and Lactobacillus fermentum reveal a genomic island for reuterin and cobalamin production.";
DNA Res. 15:151-161(2008).
Web links:
Official genome site(s):
http://www.cb.k.u-tokyo.ac.jp/hattorilab/en/projects#microbial_genome_sequencing_projects
Other web sites:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=18979
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Lfer_IFO3956
 EBI Proteome Analysis page



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