Home Proteomes Families Hamap-Scan Documents Downloads Links
HAMAP: Leptospira biflexa serovar Patoc (strain Patoc 1 / Ames) complete proteome
General information

Species:  Leptospira biflexa serovar Patoc (strain Patoc 1 / Ames)
Species code: LEPBA
Taxonomy: Bacteria; Spirochaetes; Spirochaetales; Leptospiraceae; Leptospira (TaxID: 355278) [NEWT/ NCBI]
Description: Leptospirosis is one of the most common zoonotic diseases in the world, resulting in high morbidity and mortality in humans and affecting global livestock production. Most infections are caused by either L.borgpetersenii or L.interrogans, bacteria that vary in their distribution in nature and rely on different modes of transmission. L.borgpetersenii uses a host-to-host mode of transmission, whereas L.interrogans is usually acquired from contaminated surface water.

Leptospira biflexa is a free-living, saprophytic, aquatic spirochete. Its sequence will provide insights the differences between saprophytic and pathogenic species. L. biflexa serovar Patoc strain Patoc1, was initially isolated from stream water. Two strains that have been maintained separately for 17 years have been sequenced. One was maintained in the collection of the National Reference Center of Leptospira (Institut Pasteur, Paris, France) and designated the Paris strain (LEPBP); the second strain was derived from the same source but kept in the culture collection at the National Animal Disease Center (NADC), Ames, IA since 1990 and is designated the Ames strain.
Properties: Presence of flagella: Yes
Human pathogen: No
Interaction: Saprophyte
Number of membranes: 2
Number of inteins:0
Statistics: Number of LEPBA entries in the UniProt Knowledgebase: 3595 (209 in UniProtKB/Swiss-Prot + 3386 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    Patoc 1 / Ames
Genome structure:
• Chromosome I EMBL accession number CP000777 (circular; 3,603,977 bp) (download entry)
• Chromosome II EMBL accession number CP000778 (circular; 277,995 bp) (download entry)
• Plasmid p74 EMBL accession number CP000779 (circular; 74,117 bp) (download entry)
Reference(s):
[1] PubMed=18270594; [ NCBI , EBI , Israel , Japan ]
Picardeau M., Bulach D.M., Bouchier C., Zuerner R.L., Zidane N., Wilson P.J., Creno S., Kuczek E.S., Bommezzadri S., Davis J.C., McGrath A., Johnson M.J., Boursaux-Eude C., Seemann T., Rouy Z., Coppel R.L., Rood J.I., Lajus A., Davies J.K., Medigue C., Adler B. ;
"Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis.";
PLoS ONE 3:E1607-E1607(2008).
Web links:
Official genome site(s):
http://www.med.monash.edu.au/microbiology/staff/adler/leptolab.html
Other web sites:
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Lbif_Patoc1_Ames
 EBI Proteome Analysis page



Tools