HAMAP: Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) complete proteome
General information

Species:  Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Species code: LEPIN
Taxonomy: Bacteria; Spirochaetes; Spirochaetales; Leptospiraceae; Leptospira (TaxID: 189518) [NEWT/ NCBI]
Description: Leptospira interrogans causes leptospirosis whose manifestations are fever, headache, malaise, myalgia, occasionally meningitidis, sometimes jaundice, renal insufficiency, anemia and hemorrhage of the skin. Rarely lethal. Worldwide spread except in polar regions. Contamination occurs through contact of the skin or mucous membranes with contaminated water, soil or vegetation or through direct contact with urine or tissues of infected animals. Farm and pet animals, including cattle, dogs, horses and swine, rats and other rodents act as the normal carrier host; wild animals, including deer, squirrels, foxes, skunks and even reptiles and amphibians may be infected.
Properties: Presence of flagella: Yes
Human pathogen: Yes
Interaction: Animal pathogen in Mammalia
Number of membranes: 2
Number of inteins: 1
Statistics: Number of LEPIN entries in the UniProt Knowledgebase: 3676 (377 in UniProtKB/Swiss-Prot + 3299 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    56601
Genome structure:
• Chromosome I EMBL accession number AE010300 (circular; 4,338,762 bp) (download entry)
• Chromosome II EMBL accession number AE010301 (circular; 359,372 bp) (download entry)
Reference(s):
[1] MEDLINE=22598143; PubMed=12712204; [ NCBI , EBI , Israel , Japan ]
Ren S.-X., Fu G., Jiang X.-G., Zeng R., Miao Y.-G., Xu H., Zhang Y.-X., Xiong H., Lu G., Lu L.-F., Jiang H.-Q., Jia J., Tu Y.-F., Jiang J.-X., Gu W.-Y., Zhang Y.-Q., Cai Z., Sheng H.-H., Yin H.-F., Zhang Y., Zhu G.-F., Wan M., Huang H.-L., Qian Z., Wang S.-Y., Ma W., Yao Z.-J., Shen Y., Qiang B.-Q., Xia Q.-C., Guo X.-K., Danchin A., Saint Girons I., Somerville R.L., Wen Y.-M., Shi M.-H., Chen Z., Xu J.-G., Zhao G.-P. ;
"Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing.";
Nature 422:888-893(2003).
Web links:
CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Leptospira&GLspecies=interrogans&GLstrain=56601
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid189518%5Borgn%5D
GenoList: http://bioinfo.hku.hk/GenoList/index.pl?database=leptolist
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Lint_56601
JVCI CMR: http://cmr.jcvi.org/tigr-scripts/CMR/GenomePage.cgi?database=ntli02
Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Leptospira_interrogans.html
PEDANT: http://pedant.gsf.de/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p293_Lep_inter
 EBI Proteome Analysis page



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