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HAMAP: Nitratiruptor sp. (strain SB155-2) complete proteome
General information

Species:  Nitratiruptor sp. (strain SB155-2)
Species code: NITSB
Taxonomy: Bacteria; Proteobacteria; Epsilonproteobacteria; Nitratiruptor (TaxID: 387092) [NEWT/ NCBI]
Description: Nitratiruptor sp. (strain SB155-2) is a deep-sea vent microaerobic bacterium phylogenetically associated with the epsilonproteobacteria. This strain was isolated in the vicinity of a deep-sea vent occurring in the Iheya North hydrothermal field, in Okinawa, Japan. This rod-shaped bacterium grows chemolithoautotrophically and can utilize a wide spectrum of electron donors and acceptors (i.e. hydrogen, sulfur compounds, nitrate and oxygen). It can occupy different ecological niches, and its metabolic versatility probably enables it to adapt to the geochemical variability in deep-sea hydrothermal environments. Furthermore, fitting to its metal-rich niche, this strain contains a wide array of mineral transport systems including detoxification mechanisms of heavy metals such as arsenate, cadmium, and copper. It probably has some symbiotic relationship with vent animals. Nitratiruptor sp. (strain SB155-2) genome lacks orthologs of virulence genes of pathogenic epsilonproteobacteria, such as type IV secretion pathway and cag pathogenicity island genes. However, it possesses many virulence genes that were identified in pathogenic epsilonproteobacteria, including genes for virulence factor mviN, hemolysin, invasion antigen ciaB, and lytic murein transglycosylase. Some of the most remarkable virulence genes in deep-sea vent epsilonproteobacteria belong to the N-linked glycosylation (NLG) gene cluster. It is increasingly recognized that pathogenic epsilonproteobacteria have virulence determinants that are not classified as virulence genes in general but do play important roles in virulence. For example, Helicobacter species have a H2-uptake hydrogenase encoded outside the pathogenicity island, which is essential for its efficient initial colonization. Interestingly, strain SB155-2 has three different hydrogenases (one each of H2-uptake type, H2-sensing type, and H2-evolving type).
Properties: Presence of flagella: Yes
Human pathogen: No
Interaction: No
Number of membranes: 2
Number of inteins:0
Statistics: Number of NITSB entries in the UniProt Knowledgebase: 1843 (242 in UniProtKB/Swiss-Prot + 1601 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    SB155-2
Genome structure:
Chromosome EMBL accession number AP009178 (circular; 1,877,931 bp) (download entry)
Reference(s):
[1] PubMed=17615243; [ NCBI , EBI , Israel , Japan ]
Nakagawa S., Takaki Y., Shimamura S., Reysenbach A.-L., Takai K., Horikoshi K. ;
"Deep-sea vent epsilon-proteobacterial genomes provide insights into emergence of pathogens.";
Proc. Natl. Acad. Sci. U.S.A. 104:12146-12150(2007).
Web links:
Official genome site(s):
http://www.jamstec.go.jp/e/
Other web sites:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid387092%5Borgn%5D
Genome Atlas: http://www.cbs.dtu.dk/services/gwBrowser/project.php?pid=18963
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Nitr_SB1552
PEDANT: http://pedant.gsf.de/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p18963_Nit_sp
 EBI Proteome Analysis page



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