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Species code:	RICTY
Taxonomy:	Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; Rickettsiaceae; Rickettsieae; Rickettsia; typhus group (TaxID: 257363) [NEWT/ NCBI]
Description:	Rickettsia typhi is the causative agent of murine typhus or endemic typhus. Infection with Rickettsia typhi causes headache, fever, myalgia and leads to multisystem disease, including infection of the brain, lung, liver, kidney and heart. In severe cases R.typhi can cause meningoencephalitis, interstitial pneumonia and disseminated vascular lesions. It can be transmitted to the mammalian host by the bite of an infected flea or louse but the most important mechanism of inoculation is through the feces of the vector. Although distributed worldwide, it is mostly present in warm coastal areas harbouring large rat populations.
Properties:	Presence of flagella: No Human pathogen: Yes Interaction: Animal pathogen in Mammalia (intracellular obligate) Number of membranes: 2 Number of inteins:0
Statistics:	Number of RICTY entries in the UniProt Knowledgebase: 836 (408 in UniProtKB/Swiss-Prot + 428 in UniProtKB/TrEMBL)

Genome structure:	Chromosome EMBL accession number AE017197 (circular; 1,111,496 bp) (download entry)
Reference(s):	[1] PubMed=15317790; [ NCBI , EBI , Israel , Japan ] McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E., McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E., Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A., Hong C., Yu X.-J., Walker D.H., Weinstock G.M. ; "Complete genome sequence of Rickettsia typhi and comparison with sequences of other Rickettsiae."; J. Bacteriol. 186:5842-5855(2004).
Web links:	Official genome site(s): http://www.hgsc.bcm.tmc.edu/projects/microbial/Rtyphi/ Other web sites: CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Rickettsia&GLspecies=typhi&GLstrain=Wilmington Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid257363%5Borgn%5D GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Rtyp_WILMINGTON JVCI CMR: http://cmr.jcvi.org/tigr-scripts/CMR/GenomePage.cgi?database=ntrt01 Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Rickettsia_typhi.html PATRIC: http://patric.vbi.vt.edu/genome/overview.php?genomeId=2633 PEDANT: http://pedant.gsf.de/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p10679_Ric_typhi  EBI Proteome Analysis page  UniProtKB/Swiss-Prot document

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