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HAMAP: Ruthia magnifica subsp. Calyptogena magnifica complete proteome
General information

Species:  Ruthia magnifica subsp. Calyptogena magnifica
Species code: RUTMC
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; sulfur-oxidizing symbionts (TaxID: 413404) [NEWT/ NCBI]
Description: Intracellular, sulfur-oxiding endosymbiont of Calyptogena magnifica, a giant clam living in deep sea hydrothermal vents. Ruthia magnifica is predicted to encode all the metabolic pathways typical of free-living chemoautotrophs, including carbon fixation, via the Calvin.Benson-Bassham pathway using energy derived from sulfur oxidation, nitrogen assimilation (nitrate and ammonia), and biosynthetic pathways for 20 amino acid and 10 cofactors/vitamins. The clam depends on this gammaproteobacteria for its nutrition. Few substrate-specific transporters were found, suggesting that the symbionts are leaky or that the host actively digests symbiont cells; putative degradative stages of symbionts are observed within C. magnifica bacteriocytes. The symbiont is also lacking the key cell division protein FtsZ suggesting that, like Chlamydia spp., intracellular division may not proceed through usual pathways. It is lacking one of the enzymes required for full cell wall biosynthesis. R. magnifica has the largest genome of any intracellular symbiont sequenced to date and may represent an early intermediate in the evolution toward a plastid-like chemoautotrophic organelle. An additional paper further describing the bacteria has been published (PMID 21304746) (adapted from PMID 17303757).
Properties: Presence of flagella: not known
Human pathogen: No
Interaction: Animal endosymbiont in Calyptogena magnifica (intracellular)
Number of membranes: 2
Number of inteins:0
Statistics: Number of RUTMC entries in the UniProt Knowledgebase: 976 (234 in UniProtKB/Swiss-Prot + 742 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:   
Genome structure:
Chromosome EMBL accession number CP000488 (circular; 1,160,782 bp) (download entry)
Reference(s):
[1] PubMed=17303757; [ NCBI , EBI , Israel , Japan ]
Newton I.L.G., Woyke T., Auchtung T.A., Dilly G.F., Dutton R.J., Fisher M.C., Fontanez K.M., Lau E., Stewart F.J., Richardson P.M., Barry K.W., Saunders E., Detter J.C., Wu D., Eisen J.A., Cavanaugh C.M. ;
"The Calyptogena magnifica chemoautotrophic symbiont genome.";
Science 315:998-1000(2007).
Web links:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid413404%5Borgn%5D
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Cmag_CM
PEDANT: http://pedant.gsf.de/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p16841_Rut_magni
 EBI Proteome Analysis page



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