HAMAP: Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) complete proteome
General information

Species:  Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)
Species code: SALPB
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Salmonella; Salmonella enterica subsp. enterica serovar Paratyphi B (TaxID: 1016998) [NEWT/ NCBI]
Description: Salmonella is a Gram-negative bacterium, a cylindrical rod of size about 2 microns by 0.5 microns. Salmonella Paratyphi B causes enteric fever in humans; the disease closely resembles typhoid fever, which is caused by the related serovar Salmonella Typhi. Salmonella Paratyphi B multiplies in the gastrointestinal tract of humans, penetrates the intestinal mucosa and is transferred to deeper tissues such as the liver and spleen where it survives in macrophages. The incubation period is 7 to 14 days, and the patient is often seriously ill with symptoms including fever, diarrhea, and abdominal pain. The disease has a prolonged course of 3 to 4 weeks, unless antibiotic therapy is used.

Salmonella Paratyphi B is host-specialized, for it grows well and causes disease only in humans, who usually acquire it by ingestion human-fecally contaminated water or food. This specific strain of S. Paratyphi was isolated from the stool of a woman in Penang, Malaysia. It can be obtained from the Salmonella Genetic Stock Center as SGSC4150. It is susceptible to antibiotics (modified from http://genome.wustl.edu/genomes/view/salmonella_enterica_serovar_paratyphi_b/).
Properties: Presence of flagella: Yes
Human pathogen: Yes
Interaction: Animal pathogen in Mammalia
Number of membranes: 2
Number of inteins:0
Statistics: Number of SALPB entries in the UniProt Knowledgebase: 5559 (716 in UniProtKB/Swiss-Prot + 4843 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    ATCC BAA-1250 / SPB7
Genome structure:
Chromosome EMBL accession number CP000886 (circular; 4,858,887 bp) (download entry)
Reference(s):
[1] McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S., Fulton R., Cordes M., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W., Johnson M., Thiruvilangam P., Wilson R. ;
Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
Web links:
Official genome site(s):
http://genome.wustl.edu/genomes/view/salmonella_enterica_serovar_paratyphi_b/
Other web sites:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?db=genomeprj&cmd=Retrieve&dopt=Overview&list_uids=27803
ERIC: http://www.ericbrc.org/portal/eric/salmonellaparatyphibspb7
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Sent_ParatyphiB_SPB7
 EBI Proteome Analysis page



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