Home HAMAP-Scan Families Proteomes Documents Downloads Links
HAMAP: Salmonella schwarzengrund (strain CVM19633) complete proteome
General information

Species:  Salmonella schwarzengrund (strain CVM19633)
Species code: SALSV
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Salmonella (TaxID: 439843) [NEWT/ NCBI]
Description: Salmonella species belong to the group of Enterobactericiae. These bacteria were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The majority of the components of these bacteria are identical, and at the DNA level, they are between 95% and 99% identical. Many Salmonella enterica are involved in causing diseases of the intestine (enteric means pertaining to the intestine). The nontyphoidal Salmonella are the leading cause of bacterial food borne illness in humans, making these pathogens an immediate biomedical, public health, and biodefense concern. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria, which then leads to systemic spread.

Salmonella schwarzengrund (strain CVM19633) is the predominant cause of salmonellosis in Southeast Asia, a major source of imported food products to the United States. It was also the cause of the first recognized outbreak of fluoroquinolone-resistant salmonellosis in the U.S.. Recent reports suggest that high-level fluoroquinolone resistance is emerging in S. schwarzengrund in different parts of the world. This serovar is remarkably disposed to nosocomial spread, and presents a unique opportunity to identify factors that facilitate this important type of transmission. MDR strain CVM19633 and susceptible strain SL480 belong to the S. schwarzengrund serovar.
Properties: Presence of flagella: Yes
Human pathogen: Yes
Interaction: Animal pathogen in Mammalia
Number of membranes: 2
Number of inteins:0
Statistics: Number of SALSV entries in the UniProt Knowledgebase: 4602 (712 in UniProtKB/Swiss-Prot + 3890 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    CVM19633
Genome structure:
• Chromosome EMBL accession number CP001127 (circular; 4,709,075 bp) (download entry)
• Plasmid pCVM19633_110 EMBL accession number CP001125 (circular; 110,227 bp) (download entry)
• Plasmid pCVM19633_4 EMBL accession number CP001126 (circular; 4,585 bp) (download entry)
Reference(s):
[1] Ravel J., Fricke W.F., White D., McDermott P., Mammel M., Rosovitz M., Leclerc J., Cebula T., Sebastian Y. ;
"Complete genome of Salmonella schwarzengrund strain CVM19633.";
Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
Web links:
Official genome site(s):
http://msc.jcvi.org/salmonella/salmonella_enterica_subsp__enterica_serovar_schwarzengrund_str__cvm19633/index.shtml
Other web sites:
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Sent_CVM19633
PEDANT: http://pedant.gsf.de/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p19459_Sal_enter
 EBI Proteome Analysis page



Tools