Home Proteomes Families Hamap-Scan Documents Downloads Links
HAMAP: Salmonella typhi complete proteome
General information

Species:  Salmonella typhi
Species code: SALTI
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Salmonella (TaxID: 90370) [NEWT/ NCBI]
Description: Gram-negative rod with peritrichous flagella. It is the aetiological agent of the typhoid fever, a serious disease of humans leading to 600'000 annual fatalities. Many S.enterica serovars actively invade the mucosal surface of the intestine but are normally contained in healthy individuals by the local immune defence mechanisms. However S.typhi has evolved the ability to spread to the deeper tissues of humans, including liver, spleen and bone marrow. Humans are the only known natural host of S.typhi, with S.typhi showing limited pathogenicity for most animals. S.typhi CT18 is an example of an emerging multiple drug resistant microorganism. Strain Ty2 has no plasmids.
Properties: Presence of flagella: Yes
Human pathogen: Yes
Interaction: Animal pathogen in Mammalia
Number of membranes: 2
Number of inteins:0
Statistics: Number of SALTI entries in the UniProt Knowledgebase: 4876 (1339 in UniProtKB/Swiss-Prot + 3537 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    CT18
Genome structure:
• Chromosome EMBL accession number AL513382 (circular; 4,809,037 bp) (download entry)
• Plasmid pHCM1 EMBL accession number AL513383 (circular; 218,160 bp) (download entry)
• Plasmid pHCM2 EMBL accession number AL513384 (linear; 106,516 bp) (download entry)
Reference(s):
[1] MEDLINE=21534947; PubMed=11677608; [ NCBI , EBI , Israel , Japan ]
Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J., Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M., Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A., Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T., Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A., Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G. ;
"Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18.";
Nature 413:848-852(2001).
Web links:
Official genome site(s):
http://www.sanger.ac.uk/Projects/S_typhi/
Other web sites:
CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Salmonella&GLspecies=enterica&GLstrain=typhiCT18
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?db=genomeprj&cmd=Retrieve&dopt=Overview&list_uids=236
ERIC: http://www.ericbrc.org/portal/eric/salmonellatyphict18
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Sent_CT18
JVCI CMR: http://cmr.jcvi.org/tigr-scripts/CMR/GenomePage.cgi?database=ntst03
Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Salmonella_enterica.html
PEDANT: http://pedant.gsf.de/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p236_Sal_enter
 EBI Proteome Analysis page

Strain:    ATCC 700931 / Ty2
Genome structure:
Chromosome EMBL accession number AE014613 (circular; 4,791,961 bp) (download entry)
Reference(s):
[1] MEDLINE=22531367; PubMed=12644504; [ NCBI , EBI , Israel , Japan ]
Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R. ;
"Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18.";
J. Bacteriol. 185:2330-2337(2003).
Web links:
Official genome site(s):
http://www.genome.wisc.edu/sequencing/sty2.htm
Other web sites:
CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Salmonella&GLspecies=enterica&GLstrain=Ty2
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=371
ERIC: http://www.ericbrc.org/portal/eric/salmonellatyphity2
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Sent_TYPHI_TY2
JVCI CMR: http://cmr.jcvi.org/tigr-scripts/CMR/GenomePage.cgi?database=ntst04
PEDANT: http://pedant.gsf.de/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p371_Sal_enter
 EBI Proteome Analysis page



Tools