HAMAP proteomes
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)

General information

Species:  Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
Species code: STRAW
Taxonomy: Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces (TaxID: 227882) [NEWT/ NCBI]
Description: The genus Streptomyces consists of soil and water Gram positive filamentous bacteria well known for their ability to produce complex secondary metabolites including many antibiotics. Additionally they undergo complex multicellular development, with spores germinating to form a branched, multinucleoid substrate mycelium, which then produces an aerial mycelium which septates into uninucleoid spores. Streptomyces is also unusual in having linear chromosomes with terminal inverted repeats with terminal proteins covalently bound to their 5' ends.

Streptomyces avermitilis produces secondary metabolites, one of which, avermectin, is commercially important in human and veterinary medicine.
Properties: Presence of flagella: No
Human pathogen: No
Interaction: No
Number of membranes: 1

Genome(s) sequenced

Strain:    ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680
Genome structure:
• Chromosome EMBL accession number BA000030 (linear; 9,025,608 bp) (download entry)
• Plasmid SAP1 EMBL accession number AP005645 (linear; 94,287 bp) (download entry)
Reference(s):
[1] Pubmed=11572948;
Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M. ;
"Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.";
Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
[2] Pubmed=12692562;
Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S. ;
"Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.";
Nat. Biotechnol. 21:526-531(2003).
Web links:
Official genome site(s):
http://avermitilis.ls.kitasato-u.ac.jp/
http://www.bio.nite.go.jp/dogan/MicroTop?GENOME_ID=sav_G1
Other web sites:
CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Streptomyces&GLspecies=avermitilis&GLstrain=MA4680
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid227882%5Borgn%5D
PEDANT: http://pedant.helmholtz-muenchen.de/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p189_Str_averm


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