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Species code:	STRAW
Taxonomy:	Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Streptomycineae; Streptomycetaceae; Streptomyces (TaxID: 33903) [NEWT/ NCBI]
Description:	The genus Streptomyces consists of soil and water Gram positive filamentous bacteria well known for their ability to produce complex secondary metabolites including many antibiotics. Additionally they undergo complex multicellular development, with spores germinating to form a branched, multinucleoid substrate mycelium, which then produces an aerial mycelium which septates into uninucleoid spores. Streptomyces is also unusual in having linear chromosomes with terminal inverted repeats with terminal proteins covalently bound to their 5' ends. Streptomyces avermitilis produces secondary metabolites, one of which, avermectin, is commercially important in human and veterinary medicine.
Properties:	Presence of flagella: No Human pathogen: No Interaction: No Number of membranes: 1 Number of inteins: 1
Statistics:	Number of STRAW entries in the UniProt Knowledgebase: 7664 (494 in UniProtKB/Swiss-Prot + 7170 in UniProtKB/TrEMBL)

Genome structure:	• Chromosome EMBL accession number BA000030 (linear; 9,025,608 bp) (download entry) • Plasmid SAP1 EMBL accession number AP005645 (linear; 94,287 bp) (download entry)
Reference(s):	[1] MEDLINE=21477403; PubMed=11572948; [ NCBI , EBI , Israel , Japan ] Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M. ; "Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites."; Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001). [2] MEDLINE=22608306; PubMed=12692562; [ NCBI , EBI , Israel , Japan ] Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S. ; "Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis."; Nat. Biotechnol. 21:526-531(2003).
Web links:	Official genome site(s): http://avermitilis.ls.kitasato-u.ac.jp/ http://www.bio.nite.go.jp/dogan/MicroTop?GENOME_ID=sav_G1 Other web sites: CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Streptomyces&GLspecies=avermitilis&GLstrain=MA4680 Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid227882%5Borgn%5D GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Save_MA4680 JVCI CMR: http://cmr.jcvi.org/tigr-scripts/CMR/GenomePage.cgi?database=ntsa06 Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Streptomyces_avermitilis.html PEDANT: http://pedant.gsf.de/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p189_Str_averm  EBI Proteome Analysis page

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