HAMAP: Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) complete proteome

General information

Species:  Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
Species code: STRGG
Taxonomy: Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; Streptomycineae; Streptomycetaceae; Streptomyces (TaxID: 455632) [NEWT/ NCBI]
Description: The genus Streptomyces consists of soil and water Gram positive filamentous bacteria well known for their ability to produce complex secondary metabolites including many antibiotics. Additionally they undergo complex multicellular development, with spores germinating to form a branched, multinucleoid substrate mycelium, which then produces an aerial mycelium which septates into uninucleoid spores. Streptomyces is also unusual in having linear chromosomes with terminal inverted repeats with terminal proteins covalently bound to their 5' ends.

Streptomycin, the first aminoglycoside antibiotic, was discovered more than 60 years ago, is still used to treat tuberculosis and is produced commercially by S.griseus. Analysis of the genome of strain JCM 4626 / NBRC 13350 indicates the presence of 34 gene clusters or genes for the biosynthesis of known or unknown secondary metabolites.
Properties: Presence of flagella: No
Human pathogen: No
Interaction: No
Number of membranes: 1
Statistics: Number of STRGG entries in UniProtKB: 7008 (276 in UniProtKB/Swiss-Prot + 6732 in UniProtKB/TrEMBL)

Genome(s) sequenced

Strain:    JCM 4626 / NBRC 13350
Genome structure:
Chromosome EMBL accession number AP009493 (linear; 8,545,929 bp) (download entry)
Reference(s):
[1] Pubmed=18375553;
Ohnishi Y., Ishikawa J., Hara H., Suzuki H., Ikenoya M., Ikeda H., Yamashita A., Hattori M., Horinouchi S. ;
"Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.";
J. Bacteriol. 190:4050-4060(2008).
Web links:
Official genome site(s):
http://www.cb.k.u-tokyo.ac.jp/hattorilab/en/projects
Other web sites:
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=20085
GIB (DDBJ): http://gtps.ddbj.nig.ac.jp/single/index.php?spid=Sgri_NBRC13350


Tools