HAMAP: Streptococcus pneumoniae complete proteome
General information

Species:  Streptococcus pneumoniae
Species code: STRPN
Taxonomy: Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus (TaxID: 1313) [NEWT/ NCBI]
Description: Streptococci are non-motile, Gram-positive cocci with widely varying pathogenic potential that occur in pairs or chains. It is the most common bacterial cause of acute respiratory infection and otitis media and is estimated to result in over 3 millions deaths in children every year worldwide from pneumonia, bacteremia or meningitidis. Even more deaths occur among elderly people. Since 1990 the number of penicillin-resistant strains has increased and many strains are now resistant to commonly prescribed antibiotics such as penicillin, macrolides and fluoroquinones.
Properties: Presence of flagella: No
Human pathogen: Yes
Interaction: Animal commensal in Mammalia; Animal pathogen in Mammalia
Number of membranes: 1
Number of inteins:0
Statistics: Number of STRPN entries in the UniProt Knowledgebase: 2109 (498 in UniProtKB/Swiss-Prot + 1611 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    ATCC BAA-334 / TIGR4
Genome structure:
Chromosome EMBL accession number AE005672 (circular; 2,160,842 bp) (download entry)
Reference(s):
[1] MEDLINE=21357209; PubMed=11463916; [ NCBI , EBI , Israel , Japan ]
Tettelin H., Nelson K.E., Paulsen I.T., Eisen J.A., Read T.D., Peterson S.N., Heidelberg J.F., DeBoy R.T., Haft D.H., Dodson R.J., Durkin A.S., Gwinn M.L., Kolonay J.F., Nelson W.C., Peterson J.D., Umayam L.A., White O., Salzberg S.L., Lewis M.R., Radune D., Holtzapple E.K., Khouri H.M., Wolf A.M., Utterback T.R., Hansen C.L., McDonald L.A., Feldblyum T.V., Angiuoli S.V., Dickinson T., Hickey E.K., Holt I.E., Loftus B.J., Yang F., Smith H.O., Venter J.C., Dougherty B.A., Morrison D.A., Hollingshead S.K., Fraser C.M. ;
"Complete genome sequence of a virulent isolate of Streptococcus pneumoniae.";
Science 293:498-506(2001).
Web links:
CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Streptococcus&GLspecies=pneumoniae&GLstrain=TIGR4
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid170187%5Borgn%5D
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Spne_TIGR4
JVCI CMR: http://cmr.jcvi.org/tigr-scripts/CMR/GenomePage.cgi?database=bsp
Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Streptococcus_pneumoniae.html
NMPDR: http://www.nmpdr.org/FIG/wiki/rest.cgi/NmpdrPlugin/SeedViewer?pattern=170187.1;page=SearchResult
PEDANT: http://pedant.gsf.de/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p277_Str_pneum
 EBI Proteome Analysis page



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