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HAMAP: Streptococcus thermophilus (strain CNRZ 1066) complete proteome
General information

Species:  Streptococcus thermophilus (strain CNRZ 1066)
Species code: STRT1
Taxonomy: Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus (TaxID: 299768) [NEWT/ NCBI]
Description: Lactobacilli are normal inhabitants of the gastrointestinal tract of man and animals where they are widely considered to exert a number of beneficial roles including immunomodulation, interference with enteric pathogens, and maintenance of a healthy intestinal microflora. Like other lacid acid bacteria they are acid tolerant, cannot synthesize prophyrins and are strictly fermentative with lactic acid as their major metabolic end product. Streptococci are non-motile, Gram-positive cocci with widely varying pathogenic potential that occur in pairs or chains. Streptococcus thermophilus is a Gram-positive facultative anaerobe. It is used, along with Lactobacillus spp., as a starter culture for the manufacture of several important fermented dairy foods, including yogurt and mozzarella. Consequently, over 10(21) live cells are ingested annually by the human population. S. thermophilus has an important role as a probiotic, alleviating symptoms of lactose intolerance and other gastrointestinal disorders. S.thermophilus strain CNRZ 1066 was isolated from yogurt manufactured in France.
Properties: Presence of flagella: No
Human pathogen: No
Interaction: Animal commensal in Mammalia
Number of membranes: 1
Number of inteins:0
Statistics: Number of STRT1 entries in the UniProt Knowledgebase: 1590 (321 in UniProtKB/Swiss-Prot + 1269 in UniProtKB/TrEMBL)


Genome(s) sequenced

Strain:    CNRZ 1066
Genome structure:
Chromosome EMBL accession number CP000024 (circular; 1,796,226 bp) (download entry)
Reference(s):
[1] PubMed=15543133; [ NCBI , EBI , Israel , Japan ]
Bolotin A., Quinquis B., Renault P., Sorokin A., Ehrlich S.D., Kulakauskas S., Lapidus A., Goltsman E., Mazur M., Pusch G.D., Fonstein M., Overbeek R., Kyprides N., Purnelle B., Prozzi D., Ngui K., Masuy D., Hancy F., Burteau S., Boutry M., Delcour J., Goffeau A., Hols P. ;
"Complete sequence and comparative genome analysis of the dairy bacterium Streptococcus thermophilus.";
Nat. Biotechnol. 22:1554-1558(2004).
Web links:
CBS: http://www.cbs.dtu.dk/services/GenomeAtlas/show-genus.php?kingdom=Bacteria&GLgenus=Streptococcus&GLspecies=thermophilus&GLstrain=CNRZ1066
Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&Cmd=DetailsSearch&Term=txid299768%5Borgn%5D
GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Sthe_CNRZ1066
JVCI CMR: http://cmr.jcvi.org/tigr-scripts/CMR/GenomePage.cgi?database=ntst08
Karyn's Genomes: http://www.ebi.ac.uk/2can/genomes/bacteria/Streptococcus_thermophilus.html
NMPDR: http://www.nmpdr.org/FIG/wiki/rest.cgi/NmpdrPlugin/SeedViewer?pattern=299768.3;page=SearchResult
PEDANT: http://pedant.gsf.de/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p13163_Str_therm
 EBI Proteome Analysis page



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