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Species code:	VIBC3
Taxonomy:	Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio (TaxID: 345073) [NEWT/ NCBI]
Description:	Vibrio species represent a significant portion of the culturable heterotrophic bacteria of oceans, coastal waters and estuaries. Various species of this genus are devastating pathogens for finfish, shellfish and mammals. A Gram-negative, rod-shaped bacterium, V.cholerae is the etiological agent of cholera, a severe diarrheal disease that occurs most frequently in epidemic form. Cholera has been epidemic in southern Asia for at least 1000 years; epidemics are usually associated with poor sanitary conditions. Vibrio cholerae as a species includes both pathogenic and non pathogenic strains that vary in their virulence and gene content. There are 2 major serogroups that cause epidemic cholera, O1 and O139. Serogroup O1 is further classified into two biotypes, classical and El Tor, and into two major serotypes, Inaba and Ogawa. Strain O395 is a classical serotype O1 serotype strain of the Ogawa biotype. O1 strains may exhibit serotype conversion or switching between Inaba and Ogawa serotypes. O395 has been extensively used for molecular analysis of virulence factors.
Properties:	Presence of flagella: Yes Human pathogen: Yes Interaction: Animal pathogen in Mammalia Number of membranes: 2 Number of inteins:0
Statistics:	Number of VIBC3 entries in the UniProt Knowledgebase: 4193 (511 in UniProtKB/Swiss-Prot + 3682 in UniProtKB/TrEMBL)

Genome structure:	• Chromosome 1 EMBL accession number CP000626 (circular; 1,108,250 bp) (download entry) • Chromosome 2 EMBL accession number CP000627 (circular; 3,024,069 bp) (download entry)
Reference(s):	[1] Heidelberg J. ; Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
Web links:	Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=15667 GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Vcho_O395 GOLD: http://genomesonline.org/GOLD_CARDS/Gc00557.html img/geba: http://img.jgi.doe.gov/cgi-bin/geba/main.cgi?section=TaxonDetail&page=taxonDetail&taxon_oid=640427151 NMPDR: http://www.nmpdr.org/FIG/wiki/rest.cgi/NmpdrPlugin/SeedViewer?pattern=345073.6;page=SearchResult PATRIC: http://patricbrc.vbi.vt.edu/portal/portal/patric/Genome?cType=genome&cId=35538 PEDANT: http://pedant.gsf.de/pedant3htmlview/pedant3view?Method=analysis&Db=p3_p15667_Vib_chole  EBI Proteome Analysis page

Genome structure:	• Chromosome I EMBL accession number CP001235 (circular; 3,024,078 bp) (download entry) • Chromosome II EMBL accession number CP001236 (circular; 1,111,222 bp) (download entry)
Reference(s):	[1] PubMed=19115014; [ NCBI , EBI , Israel , Japan ] Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J., Wang W., Wang J., Qian W., Li D., Wang L. ; "A recalibrated molecular clock and independent origins for the cholera pandemic clones."; PLoS ONE 3:E4053-E4053(2008).
Web links:	Entrez Genome Project: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=genomeprj&cmd=ShowDetailView&TermToSearch=32853 GIB (DDBJ): http://gib.genes.nig.ac.jp/single/index.php?spid=Vcho_O395_NANKAI GOLD: http://genomesonline.org/GOLD_CARDS/Gc00985.html PATRIC: http://patricbrc.vbi.vt.edu/portal/portal/patric/Genome?cType=genome&cId=35538  EBI Proteome Analysis page

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