HAMAP annotation rule MF_00004
Send feedback


Accession MF_00004
Dates 1-JUN-2001 (Created)
15-MAR-2013 (Last updated, Version 26)
Name Aden_phosphoribosyltr
Scope Bacteria
Archaea
Triggered by



Identifier
APT
Protein name
RecName: Full=Adenine phosphoribosyltransferase;
Short=APRT;
EC=2.4.2.7;
Gene name
apt


FUNCTION Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity).
CATALYTIC ACTIVITY AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.
PATHWAY Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine; step 1/1.
SUBUNIT Homodimer (By similarity).
SUBCELLULAR LOCATION Cytoplasm (By similarity).
SIMILARITY Belongs to the purine/pyrimidine phosphoribosyltransferase family.


Cytoplasm
Transferase
Glycosyltransferase
Purine salvage


GO:0003999; Molecular function: adenine phosphoribosyltransferase activity.
GO:0006168; Biological process: adenine salvage.
GO:0009116; Biological process: nucleoside metabolic process.
GO:0005737; Cellular component: cytoplasm.


Pfam PF00156; Pribosyltran; 1;
TIGRFAMs TIGR01090; apt; 1;
PROSITE PS00103; PUR_PYR_PR_TRANSFER; 1;


Size range: 165-223 amino acids
Related Rules: None
Template: P69503 (APT_ECOLI)
Fusion: None


View rule in raw text format (no links)