HAMAP

Accession	MF_00006
Dates	1-JUN-2001 (Created) 26-MAY-2011 (Last updated, Version 39)

Data class

Protein

Predictors

HAMAP; MF_00006; [distribution of match scores in UniProtKB];[seed alignment for MF_00006]

Names

Arg_succ_lyase

Identifier

ARLY

Protein name

RecName: Full=Argininosuccinate lyase; Short=ASAL; EC=4.3.2.1; AltName: Full=Arginosuccinase;

Gene name

argH

CATALYTIC ACTIVITY: 2-(N(omega)-L-arginino)succinate = fumarate + L-arginine.

PATHWAY: Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

Pfam	PF00206; Lyase_1; 1;
PRINTS	PR00145; ARGSUCLYASE; 1; PR00149; FUMRATELYASE; 1;
TIGRFAMs	TIGR00838; ArgH; 1;
PROSITE	PS00163; FUMARATE_LYASES; 1;

Cytoplasm, Amino-acid biosynthesis, Arginine biosynthesis, Lyase.

GO:0004056; Molecular function: argininosuccinate lyase activity.
GO:0006526; Biological process: arginine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Size range:	411-508 amino acids
Related UniRules:	None
Template:	P11447 (ARLY_ECOLI)
Scope:	Bacteria Archaea
Fusion:	Nter: <ATP-grasp domain>; Cter: MF_01105 (argA), <Unknown>
Duplicate:	in AGRT5, BACSK, PSEPF, RHILO, RHIME
Plasmid encoded:	in RHILO, RHIME