HAMAP annotation rule MF_00024
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Accession MF_00024
Dates 1-JUN-2001 (Created)
2-OCT-2012 (Last updated, Version 27)
Name CobD_CbiB
Scope Bacteria
Archaea
Triggered by



case <OC:Salmonella>
Identifier
CBIB
else
Identifier
COBD
end case
case <OC:Salmonella>
Protein name
RecName: Full=Cobalamin biosynthesis protein CbiB;
else case <OC:Bacteria> and not <OC:Salmonella>
Protein name
RecName: Full=Cobalamin biosynthesis protein CobD;
else case <OC:Archaea>
Protein name
RecName: Full=Probable cobalamin biosynthesis protein CobD;
end case
case <OC:Salmonella>
Gene name
cbiB
else
Gene name
cobD
end case


case <OC:Salmonella>
FUNCTION Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. However, the true cosubstrate could be (R)-1-amino-2-propanol O-2-phosphate, leading to cobinamide phosphate (By similarity).
else
FUNCTION Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity).
end case
PATHWAY Cofactor biosynthesis; adenosylcobalamin biosynthesis.
SUBCELLULAR LOCATION Cell membrane; Multi-pass membrane protein (Potential).
SIMILARITY Belongs to the CobD/CbiB family.


Cell membrane
Cobalamin biosynthesis
Membrane
Transmembrane
Transmembrane helix


GO:0015420; Molecular function: cobalamin-transporting ATPase activity.
GO:0005886; Cellular component: plasma membrane.


TIGRFAMs TIGR00380; CobD; 1;


General Transmembrane; -; 5-6; trigger=yes;


Size range: 283-342 amino acids
Related Rules: None
Template: Q05600 (CBIB_SALTY)
Fusion: None
Comments: Called cbiB in Salmonella


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