HAMAP annotation rule MF_00047
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Accession MF_00047
Dates 1-JUN-2001 (Created)
16-AUG-2010 (Last updated, Version 30)
Name Dala_Dala_lig
Scope Bacteria
Triggered by



Identifier
DDL
Protein name
RecName: Full=D-alanine--D-alanine ligase;
EC=6.3.2.4;
AltName: Full=D-Ala-D-Ala ligase;
AltName: Full=D-alanylalanine synthetase;
Gene name
ddl


FUNCTION Cell wall formation (By similarity).
CATALYTIC ACTIVITY ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.
PATHWAY Cell wall biogenesis; peptidoglycan biosynthesis.
SUBCELLULAR LOCATION Cytoplasm (By similarity).
SIMILARITY Belongs to the D-alanine--D-alanine ligase family.


Cell shape
Cell wall biogenesis/degradation
Cytoplasm
Ligase
Peptidoglycan synthesis


GO:0008716; Molecular function: D-alanine-D-alanine ligase activity.
GO:0009252; Biological process: peptidoglycan biosynthetic process.
GO:0005737; Cellular component: cytoplasm.


Pfam PF07478; Dala_Dala_lig_C; 1;
PF01820; Dala_Dala_lig_N; 1;
TIGRFAMs TIGR01205; D_ala_D_alaTIGR; 1;
PROSITE PS00843; DALA_DALA_LIGASE_1; 1;
PS00844; DALA_DALA_LIGASE_2; 1;
PS50975; ATP_GRASP; 1; trigger=PRU00409;


Size range: 291-396 amino acids
Related Rules: None
Templates: P07862 (DDLB_ECOLI); P0A6J8 (DDLA_ECOLI): [Recover all]
Fusion: Nter: MF_00046 (murC); Cter: None
Comments: Short BACSU, but does not seem to be extendable


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