HAMAP rule MF_00050
General rule information
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| Accession | MF_00050 |
| Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 35) |
| Name | EF_Ts |
| Scope(s) |
Bacteria Plastid |
| Template(s) | P0A6P1 (EFTS_ECOLI); P43895 (EFTS_THET8); [ Recover all ] |
| Triggered by |
case c? <OC:Bacteria> or <OG:Plastid>
HAMAP; MF_00050 (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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| case <OC:Bacteria> | |
| Identifier | EFTS |
| Protein name | RecName: Full=Elongation factor Ts; Short=EF-Ts; |
| Gene name | Name=tsf; |
| else case <OG:Chloroplast> | |
| Identifier | EFTS |
| Protein name | RecName: Full=Elongation factor Ts, chloroplastic; Short=EF-Ts; |
| Gene name | Name=tsf; |
| end case | |
Comments
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| FUNCTION | Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. |
| case not <OG:Chloroplast> | |
| SUBCELLULAR LOCATION | Cytoplasm. |
| end case | |
| case <OG:Chloroplast> | |
| SUBCELLULAR LOCATION | Plastid, chloroplast. |
| end case | |
| SIMILARITY | Belongs to the EF-Ts family. |
Keywords
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| case not <OG:Chloroplast> | |
| Cytoplasm | |
| end case | |
| Elongation factor | |
| Protein biosynthesis | |
Gene Ontology
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| GO:0003746; Molecular function:translation elongation factor activity | |
| GO:0006414; Biological process:translational elongation | |
| case not <OG:Chloroplast> | |
| GO:0005737; Cellular component:cytoplasm | |
| end case | |
| case <OG:Chloroplast> | |
| GO:0009507; Cellular component:chloroplast | |
| end case | |
Cross-references
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| Pfam | PF00889; EF_TS; 1; |
| Pfam | PF00627; UBA; 1; |
| NCBIfam | TIGR00116; Tsf; 1; |
| PROSITE | PS01126; EF_TS_1; 1; |
| PROSITE | PS01127; EF_TS_2; 1; |
Features
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| From: EFTS_ECOLI (P0A6P1) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| case <OC:Bacteria> | ||||||||||||
| REGION | 80 | 83 | /note="Involved in Mg(2+) ion dislocation from EF-Tu" | [TS]-[DE]-F-[LV] | ||||||||
| end case | ||||||||||||
Additional information
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| Size range | 196-357 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |