HAMAP

Accession	MF_00062
Dates	1-JUN-2001 (Created) 28-SEP-2010 (Last updated, Version 22)

Data class

Protein

Predictors

HAMAP; MF_00062; [distribution of match scores in UniProtKB];[seed alignment for MF_00062]

Names

Sulf_adenylyltr_sub1

Identifier

CYSN

Protein name

RecName: Full=Sulfate adenylyltransferase subunit 1; EC=2.7.7.4; AltName: Full=ATP-sulfurylase large subunit; AltName: Full=Sulfate adenylate transferase; Short=SAT;

Gene name

cysN

FUNCTION: May be the GTPase, regulating ATP sulfurylase activity (By similarity).

CATALYTIC ACTIVITY: ATP + sulfate = diphosphate + adenylyl sulfate.

PATHWAY: Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3.

SUBUNIT: Heterodimer composed of CysD, the smaller subunit, and CysN (By similarity).

SIMILARITY: Belongs to the GTP-binding elongation factor family. CysN/nodQ subfamily.

Pfam	PF00009; GTP_EFTU; 1;
PRINTS	PR00315; ELONGATNFCT; 1;
PROSITE	PS00301; EFACTOR_GTP; 1;

ATP-binding, GTP-binding, Nucleotide-binding, Nucleotidyltransferase, Transferase.

GO:0005525; Molecular function: GTP binding.
GO:0004781; Molecular function: sulfate adenylyltransferase (ATP) activity.
GO:0000103; Biological process: sulfate assimilation.

From: CYSN_ECOLI (P23845)
Key		From		To		Description		Condition		FTGroup
NP_BIND		34		41		GTP (By similarity)		G-x(4)-G-K-S
NP_BIND		113		117		GTP (By similarity)		D-[ATC]-P-G-H
NP_BIND		168		171		GTP (By similarity)		N-K-[IM]-D

Size range:	441-494 amino acids
Related UniRules:	None
Template:	P23845 (CYSN_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: MF_00065 (cysC)
Duplicate:	None
Plasmid encoded:	in AZOBR, RHIME
Comments:	Problematic entry. N-terminal too short in MYCTU. If in a nodulating bacteria, has to be done manually because of the presence of both cysN and nodQ.