HAMAP

Accession	MF_00065
Dates	1-JUN-2001 (Created) 11-MAY-2011 (Last updated, Version 30)

Data class

Protein

Predictors

HAMAP; MF_00065; [distribution of match scores in UniProtKB];[seed alignment for MF_00065]

Names

Adenylyl_sulf_kinase

Identifier

CYSC

Protein name

RecName: Full=Adenylyl-sulfate kinase; EC=2.7.1.25; AltName: Full=APS kinase; AltName: Full=ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; AltName: Full=Adenosine-5'-phosphosulfate kinase;

Gene name

cysC

FUNCTION: Catalyzes the synthesis of activated sulfate (By similarity).

CATALYTIC ACTIVITY: ATP + adenylyl sulfate = ADP + 3'-phosphoadenylyl sulfate.

PATHWAY: Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 2/3.

SIMILARITY: Belongs to the APS kinase family.

Pfam	PF01583; APS_kinase; 1;
TIGRFAMs	TIGR00455; ApsK; 1;

Transferase, Kinase, ATP-binding, Nucleotide-binding, Phosphoprotein.

GO:0004020; Molecular function: adenylylsulfate kinase activity.
GO:0005524; Molecular function: ATP binding.
GO:0000103; Biological process: sulfate assimilation.

From: CYSC_ECOLI (P0A6J1)
Key		From		To		Description		Condition		FTGroup
NP_BIND		35		42		ATP (By similarity)		G-x(4)-G-K-[ST]
ACT_SITE		109		109		Phosphoserine intermediate (By similarity)		S

Size range:	155-214 amino acids
Related UniRules:	None
Template:	P0A6J1 (CYSC_ECOLI)
Scope:	Bacteria Archaea
Fusion:	Nter: MF_00062 (cysN), MF_00066 (sat); Cter: None
Duplicate:	in BACSU
Plasmid encoded:	in AZOBR, RHIME
Comments:	Problematic entry