Due to scheduled maintenance work, this service may not be available on Monday January 22nd between 08.00 am and 9.00 am CEST.
To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https
Annotation rule MF_00069
Send feedback

General rule information [?]

Accession MF_00069
Dates 1-JUN-2001 (Created)
28-JUL-2016 (Last updated, Version 36)
Name Hydroxylam_reduct
Scope Bacteria
Templates P31101 (HCP_DESVH); Q01770 (HCP_DESDA); P75825 (HCP_ECOLI); Q6WRT6 (HCP_RHOCA): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Hydroxylamine reductase;
AltName: Full=Hybrid-cluster protein;
AltName: Full=Prismane protein;
Gene name

Comments [?]

Function Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
Catalytic activity NH(3) + H(2)O + acceptor = hydroxylamine + reduced acceptor.
case <OC:Gammaproteobacteria> and <FTGroup:1>
Cofactor [2Fe-2S] cluster
Note: Binds 1 [2Fe-2S] cluster.
end case
case not <OC:Gammaproteobacteria> and <FTGroup:2>
Cofactor [4Fe-4S] cluster
Note: Binds 1 [4Fe-4S] cluster.
end case
case <FTGroup:3>
Cofactor hybrid [4Fe-2O-2S] cluster
Note: Binds 1 hybrid [4Fe-2O-2S] cluster.
end case
Subcellular location Cytoplasm.
Similarity Belongs to the HCP family.

Keywords [?]

case <FTGroup:1> or <FTGroup:2> or <FTGroup:3>
end case
case <OC:Gammaproteobacteria> and <FTGroup:1>
end case
case not <OC:Gammaproteobacteria> and <FTGroup:2>
end case

Gene Ontology [?]

GO:0005737; Cellular component: cytoplasm.
GO:0050418; Molecular function: hydroxylamine reductase activity.
GO:0051536; Molecular function: iron-sulfur cluster binding.

Cross-references [?]

Pfam PF03063; Prismane; 1;
TIGRFAMs TIGR01703; hybrid_clust; 1;

Features [?]

case <OC:Gammaproteobacteria>
From: HCP_ECOLI (P75825)
Key     From     To       Description   Tag   Condition   FTGroup
METAL     3     3       Iron-sulfur (2Fe-2S)     C   1
METAL     6     6       Iron-sulfur (2Fe-2S)     C   1
METAL     18     18       Iron-sulfur (2Fe-2S)     C   1
METAL     25     25       Iron-sulfur (2Fe-2S)     C   1
end case
case not <OC:Gammaproteobacteria>
From: HCP_DESVH (P31101)
METAL     3     3       Iron-sulfur (4Fe-4S)     C   2
METAL     6     6       Iron-sulfur (4Fe-4S)     C   2
METAL     15     15       Iron-sulfur (4Fe-4S)     C   2
METAL     21     21       Iron-sulfur (4Fe-4S)     C   2
end case
METAL     244     244       Iron-oxo-sulfur (4Fe-2O-2S); via tele nitrogen     H   3
METAL     268     268       Iron-oxo-sulfur (4Fe-2O-2S)     E   3
METAL     312     312       Iron-oxo-sulfur (4Fe-2O-2S)     C   3
METAL     406     406       Iron-oxo-sulfur (4Fe-2O-2S); via persulfide group     C   3
METAL     434     434       Iron-oxo-sulfur (4Fe-2O-2S)     C   3
METAL     459     459       Iron-oxo-sulfur (4Fe-2O-2S)     C   3
METAL     494     494       Iron-oxo-sulfur (4Fe-2O-2S)     E   3
METAL     496     496       Iron-oxo-sulfur (4Fe-2O-2S)     K   3
MOD_RES     406     406       Cysteine persulfide     C  

Additional information [?]

Size range 427-570 amino acids
Related rules None
Fusion None
Comments Possible wrong start in THEMA and ACIFR. Deleted domain in THEMA/METTH.