HAMAP rule MF_00074
General rule information
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| Accession | MF_00074 |
| Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 35) |
| Name | 16SrRNA_methyltr_G |
| Scope(s) |
Bacteria |
| Template(s) | P0A6U5 (RSMG_ECOLI); P25813 (RSMG_BACSU); P9WGW9 (RSMG_MYCTU); O54571 (RSMG_STRCO); [ Recover all ] |
| Triggered by |
HAMAP; MF_00074 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | RSMG |
| case <OC:Pseudomonadota> | |
| Protein name | RecName: Full=Ribosomal RNA small subunit methyltransferase G; EC=2.1.1.170; AltName: Full=16S rRNA 7-methylguanosine methyltransferase; Short=16S rRNA m7G methyltransferase; |
| else | |
| Protein name | RecName: Full=Ribosomal RNA small subunit methyltransferase G; EC=2.1.1.-; AltName: Full=16S rRNA 7-methylguanosine methyltransferase; Short=16S rRNA m7G methyltransferase; |
| end case | |
| Gene name | Name=rsmG; |
Comments
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| case <OC:Pseudomonadota> | |
| FUNCTION | Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. |
| CATALYTIC ACTIVITY | Reaction=guanosine(527) in 16S rRNA + S-adenosyl-L-methionine = N(7)- methylguanosine(527) in 16S rRNA + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:42732, Rhea:RHEA-COMP:10209, Rhea:RHEA-COMP:10210, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74269, ChEBI:CHEBI:74480; EC=2.1.1.170; |
| else case <OC:Bacillales> | |
| FUNCTION | Specifically methylates the N7 position of guanine in position 535 of 16S rRNA. |
| else case <OC:Actinomycetales> | |
| FUNCTION | Specifically methylates the N7 position of guanine in position 518 of 16S rRNA. |
| else | |
| FUNCTION | Specifically methylates the N7 position of a guanine in 16S rRNA. |
| end case | |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. |
Keywords
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Gene Ontology
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| GO:0070043; Molecular function:rRNA (guanine-N7-)-methyltransferase activity |
| GO:0006364; Biological process:rRNA processing |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF02527; GidB; 1; |
| PIRSF | PIRSF003078; GidB; 1; |
| NCBIfam | TIGR00138; GidB; 1; |
Features
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| From: RSMG_THET8 (Q9LCY2) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 111 | 113 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
[DE]-x-[TS] | ||||||||
| BINDING | 139 | 140 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
[AGVILSC]-[EYQ] | ||||||||
| BINDING | 88 | 88 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
G | ||||||||
| BINDING | 93 | 93 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
[FLYMQ] | ||||||||
| BINDING | 158 | 158 | /ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789" |
[RQK] | ||||||||
Additional information
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| Size range | 178-288 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: <SpoU_methylase> |