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HAMAP rule MF_00074

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General rule information [?]

Accession MF_00074
Dates 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 35)
Name 16SrRNA_methyltr_G
Scope(s) Bacteria
Template(s) P0A6U5 (RSMG_ECOLI); P25813 (RSMG_BACSU); P9WGW9 (RSMG_MYCTU); O54571 (RSMG_STRCO); [ Recover all ]
Triggered by HAMAP; MF_00074 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RSMG
case <OC:Pseudomonadota>
Protein name RecName: Full=Ribosomal RNA small subunit methyltransferase G;
                 EC=2.1.1.170;
AltName: Full=16S rRNA 7-methylguanosine methyltransferase;
                 Short=16S rRNA m7G methyltransferase;
else
Protein name RecName: Full=Ribosomal RNA small subunit methyltransferase G;
                 EC=2.1.1.-;
AltName: Full=16S rRNA 7-methylguanosine methyltransferase;
                 Short=16S rRNA m7G methyltransferase;
end case
Gene name Name=rsmG;

Comments [?]

case <OC:Pseudomonadota>
FUNCTIONSpecifically methylates the N7 position of guanine in position 527 of 16S rRNA.
CATALYTIC ACTIVITY Reaction=guanosine(527) in 16S rRNA + S-adenosyl-L-methionine = N(7)- methylguanosine(527) in 16S rRNA + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:42732, Rhea:RHEA-COMP:10209, Rhea:RHEA-COMP:10210, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:74269, ChEBI:CHEBI:74480; EC=2.1.1.170;
else case <OC:Bacillales>
FUNCTIONSpecifically methylates the N7 position of guanine in position 535 of 16S rRNA.
else case <OC:Actinomycetales>
FUNCTIONSpecifically methylates the N7 position of guanine in position 518 of 16S rRNA.
else
FUNCTIONSpecifically methylates the N7 position of a guanine in 16S rRNA.
end case
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.

Keywords [?]


Gene Ontology [?]

GO:0070043; Molecular function:rRNA (guanine-N7-)-methyltransferase activity
GO:0006364; Biological process:rRNA processing
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF02527; GidB; 1;
PIRSF PIRSF003078; GidB; 1;
NCBIfam TIGR00138; GidB; 1;

Features [?]

From: RSMG_THET8 (Q9LCY2)
Key From To Description Tag Condition FTGroup
BINDING 111 113 /ligand="S-adenosyl-L-methionine"
/ligand_id="ChEBI:CHEBI:59789"
[DE]-x-[TS]
BINDING 139 140 /ligand="S-adenosyl-L-methionine"
/ligand_id="ChEBI:CHEBI:59789"
[AGVILSC]-[EYQ]
BINDING 88 88 /ligand="S-adenosyl-L-methionine"
/ligand_id="ChEBI:CHEBI:59789"
G
BINDING 93 93 /ligand="S-adenosyl-L-methionine"
/ligand_id="ChEBI:CHEBI:59789"
[FLYMQ]
BINDING 158 158 /ligand="S-adenosyl-L-methionine"
/ligand_id="ChEBI:CHEBI:59789"
[RQK]

Additional information [?]

Size range 178-288 amino acids
Related rules None
Fusion Nter: None Cter: <SpoU_methylase>



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