HAMAP annotation rule: MF_00080
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Accession MF_00080
Dates 1-JUN-2001 (Created)
12-MAY-2011 (Last updated, Version 28)
Data class Protein
Names IF-3




case not <OG:Chloroplast>
Identifier IF3
Protein name
RecName: Full=Translation initiation factor IF-3;
end case


case <OG:Chloroplast>
Identifier IF3C
Protein name
RecName: Full=Translation initiation factor IF-3, chloroplastic;
end case

Gene name infC
FUNCTION: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity).
SUBUNIT: Monomer (By similarity).

case not <OG:Chloroplast>
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
end case


case <OG:Chloroplast>
SUBCELLULAR LOCATION: Plastid, chloroplast.
end case

SIMILARITY: Belongs to the IF-3 family.
Pfam PF00707; IF3_C; 1;
PF05198; IF3_N; 1;
TIGRFAMs TIGR00168; InfC; 1;
PROSITE PS00938; IF3; 1;

case not <OG:Chloroplast>
end case

GO:0003743; Molecular function: translation initiation factor activity.
GO:0006413; Biological process: translational initiation.

case not <OG:Chloroplast>
GO:0005737; Cellular component: cytoplasm.
end case


case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case




Size range: 163-247 amino acids
Related UniRules: None
Template: P03000 (IF3_GEOSE); P0A707 (IF3_ECOLI); P48516 (IF3_MYXXA); Q9ACJ8 (IF3_THET2): [Recover all]
Scope: Bacteria
Plastid
Fusion: Nter: None; Cter: None
Duplicate: None
Plasmid encoded: None
Comments: Divergent second copy in NOSS1, not shown in alignment

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