HAMAP rule MF_00080
General rule information
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| Accession | MF_00080 |
| Dates | 1-JUN-2001 (Created)
11-OCT-2023 (Last updated, Version 32) |
| Name | IF_3 |
| Scope(s) |
Bacteria Plastid |
| Template(s) | P03000 (IF3_GEOSE); P0A707 (IF3_ECOLI); P48516 (IF3_MYXXA); Q9ACJ8 (IF3_THET2); [ Recover all ] |
| Triggered by |
HAMAP; MF_00080 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| case not <OG:Chloroplast> | |
| Identifier | IF3 |
| Protein name | RecName: Full=Translation initiation factor IF-3; |
| end case | |
| case <OG:Chloroplast> | |
| Identifier | IF3C |
| Protein name | RecName: Full=Translation initiation factor IF-3, chloroplastic; |
| end case | |
| Gene name | Name=infC; |
Comments
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| FUNCTION | IF-3 binds to the 30S ribosomal subunit and shifts the equilibrium between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. |
| SUBUNIT | Monomer. |
| case not <OG:Chloroplast> | |
| SUBCELLULAR LOCATION | Cytoplasm. |
| end case | |
| case <OG:Chloroplast> | |
| SUBCELLULAR LOCATION | Plastid, chloroplast. |
| end case | |
| SIMILARITY | Belongs to the IF-3 family. |
Keywords
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| case not <OG:Chloroplast> | |
| Cytoplasm | |
| end case | |
| Initiation factor | |
| Protein biosynthesis | |
Gene Ontology
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| GO:0003743; Molecular function:translation initiation factor activity | |
| GO:0006413; Biological process:translational initiation | |
| case not <OG:Chloroplast> | |
| GO:0005737; Cellular component:cytoplasm | |
| end case | |
| case <OG:Chloroplast> | |
| GO:0009507; Cellular component:chloroplast | |
| end case | |
Cross-references
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| Pfam | PF00707; IF3_C; 1; |
| Pfam | PF05198; IF3_N; 1; |
| NCBIfam | TIGR00168; InfC; 1; |
| PROSITE | PS00938; IF3; 1; |
Features
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Additional information
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| Size range | 163-247 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Divergent second copy in NOSS1, not shown in alignment |