HAMAP rule MF_00081
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_00081 |
| Accession | MF_00081 |
| Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 26) |
| Name | HrcA |
| Scope(s) |
Bacteria |
| Template(s) | P25499 (HRCA_BACSU); [ Recover all ] |
| Triggered by |
HAMAP; MF_00081 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | HRCA |
| Protein name | RecName: Full=Heat-inducible transcription repressor HrcA; |
| Gene name | Name=hrcA; |
Comments
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| FUNCTION | Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. |
| SIMILARITY | Belongs to the HrcA family. |
Keywords
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Gene Ontology
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| GO:0045892; Biological process:negative regulation of DNA-templated transcription |
Cross-references
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Features
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Additional information
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| Size range | 264-398 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Possible wrong starts in a number of sequences. See: MEDLINE=20023017; PubMed=10555317; Ahmad S., Selvapandiyan A., Bhatnagar R.K.; "A protein-based phylogenetic tree for gram-positive bacteria derived from hrcA, a unique heat-shock regulatory gene."; Int. J. Syst. Bacteriol. 49:1387-1394(1999). |