HAMAP rule MF_00083
General rule information
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| Accession | MF_00083 |
| Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 24) |
| Name | Pept_tRNA_hydro_bact |
| Scope(s) |
Bacteria |
| Template(s) | P0A7D1 (PTH_ECOLI); Q6YP15 (PTH_STAAU); [ Recover all ] |
| Triggered by |
HAMAP; MF_00083 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | PTH |
| Protein name | RecName: Full=Peptidyl-tRNA hydrolase; Short=PTH; EC=3.1.1.29; |
| Gene name | Name=pth; |
Comments
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| FUNCTION | The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. |
| CATALYTIC ACTIVITY | Reaction=an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L- amino acid + H(+); Xref=Rhea:RHEA:54448, Rhea:RHEA-COMP:10123, Rhea:RHEA-COMP:13883, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:59874, ChEBI:CHEBI:78442, ChEBI:CHEBI:138191; EC=3.1.1.29; |
| SUBUNIT | Monomer. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the PTH family. |
Keywords
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Gene Ontology
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| GO:0004045; Molecular function:aminoacyl-tRNA hydrolase activity |
| GO:0006412; Biological process:translation |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF01195; Pept_tRNA_hydro; 1; |
| NCBIfam | TIGR00447; Pth; 1; |
| PROSITE | PS01195; PEPT_TRNA_HYDROL_1; 1; |
| PROSITE | PS01196; PEPT_TRNA_HYDROL_2; 1; |
Features
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Additional information
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| Size range | 172-250 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Called spoVC in BACSU |