HAMAP annotation rule MF_00093
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Accession MF_00093
Dates 1-JUN-2001 (Created)
28-OCT-2011 (Last updated, Version 19)
Name Rel_fac_1
Scope Bacteria
Triggered by



Identifier
RF1
Protein name
RecName: Full=Peptide chain release factor 1;
Short=RF-1;
Gene name
prfA


FUNCTION Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity).
SUBCELLULAR LOCATION Cytoplasm (By similarity).
case <FT:1>
PTM Methylated by PrmC. Methylation increases the termination efficiency of RF1 (By similarity).
end case
SIMILARITY Belongs to the prokaryotic/mitochondrial release factor family.


Cytoplasm
Protein biosynthesis
case <FT:1>
Methylation
end case


GO:0016149; Molecular function: translation release factor activity, codon specific.
GO:0006415; Biological process: translational termination.
GO:0005737; Cellular component: cytoplasm.


Pfam PF00472; RF-1; 1;
TIGRFAMs TIGR00019; PrfA; 1;
PROSITE PS00745; RF_PROK_I; 1;


From: RF1_ECOLI (P0A7I0)
Key     From     To       Description   Tag   Condition   FTGroup
MOD_RES     235     235       N5-methylglutamine (By similarity)     Q  


Size range: 342-375 amino acids
Related Rules: MF_00094 (RF2)
Template: P0A7I0 (RF1_ECOLI)
Fusion: None


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