HAMAP rule MF_00093
General rule information
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| Accession | MF_00093 |
| Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 22) |
| Name | Rel_fac_1 |
| Scope(s) |
Bacteria |
| Template(s) | P0A7I0 (RF1_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_00093 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | RF1 |
| Protein name | RecName: Full=Peptide chain release factor 1; Short=RF-1; |
| Gene name | Name=prfA; |
Comments
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| FUNCTION | Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| case <FT:1> | |
| PTM | Methylated by PrmC. Methylation increases the termination efficiency of RF1. |
| end case | |
| SIMILARITY | Belongs to the prokaryotic/mitochondrial release factor family. |
Keywords
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| Cytoplasm | |
| Protein biosynthesis | |
| case <FT:1> | |
| Methylation | |
| end case | |
Gene Ontology
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| GO:0016149; Molecular function:translation release factor activity, codon specific |
| GO:0006415; Biological process:translational termination |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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Features
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| From: RF1_ECOLI (P0A7I0) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| MOD_RES | 235 | 235 | /note="N5-methylglutamine" | Q | ||||||||
Additional information
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| Size range | 342-375 amino acids |
| Related rules |
MF_00094 |
| Fusion | Nter: None Cter: None |