HAMAP

Accession	MF_00111
Dates	1-JUN-2001 (Created) 9-NOV-2012 (Last updated, Version 39)

Name

MurA

Scope

Bacteria

Triggered by

HAMAP; MF_00111 (Get profile general information and statistics)

Identifier

MURA

Protein name

RecName: Full=UDP-N-acetylglucosamine 1-carboxyvinyltransferase; EC=2.5.1.7; AltName: Full=Enoylpyruvate transferase; AltName: Full=UDP-N-acetylglucosamine enolpyruvyl transferase; Short=EPT;

Gene name

murA

FUNCTION	Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine (By similarity).
CATALYTIC ACTIVITY	Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine.
PATHWAY	Cell wall biogenesis; peptidoglycan biosynthesis.
SUBCELLULAR LOCATION	Cytoplasm (By similarity).
SIMILARITY	Belongs to the EPSP synthase family. MurA subfamily.

Cell cycle
Cell division
Cell shape
Cell wall biogenesis/degradation
Cytoplasm
Peptidoglycan synthesis
Transferase

GO:0008760; Molecular function: UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity.
GO:0009252; Biological process: peptidoglycan biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Pfam	PF00275; EPSP_synthase; 1;
TIGRFAMs	TIGR01072; MurA; 1;

From: MURA_ECOLI (P0A749)

Key

From

To

Description

Tag

Condition

FTGroup

ACT_SITE

115

115

Proton donor (By similarity)

[CD]

MOD_RES

115

115

2-(S-cysteinyl)pyruvic acid O-phosphothioketal (By similarity)

C

Size range:	414-465 amino acids
Related Rules:	None
Templates:	P0A749 (MURA_ECOLI); P33038 (MURA_ENTCC): [Recover all]
Fusion:	None
Comments:	Longer C-terminus in one copy in LEGPL; not included in size range

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