HAMAP

Accession	MF_00117
Dates	1-JUN-2001 (Created) 9-DEC-2011 (Last updated, Version 18)

Data class

Protein

Predictors

HAMAP; MF_00117; [distribution of match scores in UniProtKB];[seed alignment for MF_00117]

Names

HslO

Identifier

HSLO

Protein name

RecName: Full=33 kDa chaperonin; AltName: Full=Heat shock protein 33 homolog; Short=HSP33;

Gene name

hslO

FUNCTION: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

PTM: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive (By similarity).

SIMILARITY: Belongs to the HSP33 family.

Pfam	PF01430; HSP33; 1;

Cytoplasm, Chaperone, Disulfide bond, Redox-active center, Zinc.

GO:0051082; Molecular function: unfolded protein binding.
GO:0005737; Cellular component: cytoplasm.

From: HSLO_ECOLI (P0A6Y5)
Key		From		To		Description		Condition		FTGroup
DISULFID		230		232		Redox-active (By similarity)		C-x-C
DISULFID		263		266		Redox-active (By similarity)		C-x(2)-C

Size range:	281-341 amino acids
Related UniRules:	None
Template:	P0A6Y5 (HSLO_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	Possible wrong start in AQUAE and DEIRA