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HAMAP rule MF_00123
General rule information
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| Accession | MF_00123 |
| Dates | 1-JUN-2001 (Created)
1-JUN-2023 (Last updated, Version 36) |
| Name | Arg_tRNA_synth |
| Scope(s) |
Bacteria Archaea |
| Template(s) | P11875 (SYR_ECOLI); P46906 (SYR_BACSU); [ Recover all ] |
| Triggered by |
HAMAP; MF_00123 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | SYR |
| Protein name | RecName: Full=Arginine--tRNA ligase; EC=6.1.1.19; AltName: Full=Arginyl-tRNA synthetase; Short=ArgRS; |
| Gene name | Name=argS; |
Comments
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| CATALYTIC ACTIVITY | Reaction=ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl- tRNA(Arg); Xref=Rhea:RHEA:20301, Rhea:RHEA-COMP:9658, Rhea:RHEA- COMP:9673, ChEBI:CHEBI:30616, ChEBI:CHEBI:32682, ChEBI:CHEBI:33019, ChEBI:CHEBI:78442, ChEBI:CHEBI:78513, ChEBI:CHEBI:456215; EC=6.1.1.19; |
| case <OC:Bacteria> | |
| SUBUNIT | Monomer. |
| end case | |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the class-I aminoacyl-tRNA synthetase family. |
Keywords
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Gene Ontology
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| GO:0004814; Molecular function:arginine-tRNA ligase activity |
| GO:0005524; Molecular function:ATP binding |
| GO:0006420; Biological process:arginyl-tRNA aminoacylation |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF00750; tRNA-synt_1d; 1; |
| PRINTS | PR01038; TRNASYNTHARG; 1; |
| NCBIfam | TIGR00456; ArgS; 1; |
| PROSITE | PS00178; AA_TRNA_LIGASE_I; 1; |
Features
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| From: SYR_BACSU (P46906) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| MOTIF | 132 | 142 | /note="'HIGH' region" | [AVPG]-N-[PTIVL]-x-[KGHS]-x-[LIMFV]-[HTSGNV]-[LMIV]-[GAV]-[HGRSNQ] | ||||||||
Additional information
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| Size range | 527-671 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |
| Comments | Possible wrong start site in BORBU |