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Annotation rule MF_00134
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General rule information [?]

Accession MF_00134
Dates 1-JUN-2001 (Created)
22-OCT-2013 (Last updated, Version 30)
Name IGPS
Scope Bacteria
Archaea
Templates Q56319 (TRPC_THEMA); P00909 (TRPC_ECOLI); Q06121 (TRPC_SULSO): [Recover all]
case <OC:Bacteria>
end case

case <OC:Archaea>
end case


Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
TRPC
Protein name
RecName: Full=Indole-3-glycerol phosphate synthase;
Short=IGPS;
EC=4.1.1.48;
Gene name
trpC

Comments [?]

Catalytic activity 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO(2) + H(2)O.
Pathway Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.
Similarity Belongs to the TrpC family.

Keywords [?]


Gene Ontology [?]

GO:0004425; Molecular function: indole-3-glycerol-phosphate synthase activity.
GO:0000162; Biological process: tryptophan biosynthetic process.

Cross-references [?]

Pfam PF00218; IGPS; 1;
PROSITE PS00614; IGPS; 1;

Additional information [?]

case <OC:Bacteria>
Size range 250-305 amino acids
end case
case <OC:Archaea>
Size range 226-274 amino acids
end case
Related rules None
Fusion Nter: None; Cter: MF_00135 (trpF), MF_00211 (trpD)
Comments Possible wrong start in THEKO, SYNY3 and VIBPA