HAMAP annotation rule: MF_00141
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Accession MF_00141
Dates 1-JUN-2001 (Created)
16-MAY-2011 (Last updated, Version 21)
Data class Protein
Names EF-P



Identifier EFP
Protein name
RecName: Full=Elongation factor P;
Short=EF-P;
Gene name efp
FUNCTION: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).
PATHWAY: Protein biosynthesis; polypeptide chain elongation.
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the elongation factor P family.
Pfam PF01132; EFP; 1;
TIGRFAMs TIGR00038; Efp; 1;
PROSITE PS01275; EFP; 1;
GO:0003746; Molecular function: translation elongation factor activity.
GO:0006414; Biological process: translational elongation.
GO:0005737; Cellular component: cytoplasm.



Size range: 184-195 amino acids
Related UniRules: MF_00646 (EFPL (supersedes the current rule))
Template: P0A6N4 (EFP_ECOLI); Q76G20 (EFP_THET8): [Recover all]
Scope: Bacteria
Fusion: Nter: None; Cter: None
Duplicate: in CHLMU, CHLPN, CHLTR, LACJO, PARUW, PORGI, RHILO
Plasmid encoded: None

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